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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MIPEP
Full Name:
Mitochondrial intermediate peptidase
Alias:
MIP
Type:
Mass (Da):
80623
Number AA:
713
UniProt ID:
Q99797
International Prot ID:
IPI00241860
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005759
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0000287
GO:0003824
GO:0004175
PhosphoSite+
KinaseNET
Biological Process:
GO:0006464
GO:0006508
GO:0006627
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
P
R
R
A
G
R
G
S
L
E
A
G
I
R
A
Site 2
S37
G
I
R
A
R
R
V
S
T
S
W
S
P
V
G
Site 3
T38
I
R
A
R
R
V
S
T
S
W
S
P
V
G
A
Site 4
S39
R
A
R
R
V
S
T
S
W
S
P
V
G
A
A
Site 5
S41
R
R
V
S
T
S
W
S
P
V
G
A
A
F
N
Site 6
T88
Q
E
K
A
L
R
K
T
E
L
L
V
D
R
A
Site 7
S97
L
L
V
D
R
A
C
S
T
P
P
G
P
Q
T
Site 8
T98
L
V
D
R
A
C
S
T
P
P
G
P
Q
T
V
Site 9
T104
S
T
P
P
G
P
Q
T
V
L
I
F
D
E
L
Site 10
T154
T
M
V
E
K
L
N
T
N
V
D
L
Y
Q
S
Site 11
Y159
L
N
T
N
V
D
L
Y
Q
S
L
Q
K
L
L
Site 12
S161
T
N
V
D
L
Y
Q
S
L
Q
K
L
L
A
D
Site 13
S174
A
D
K
K
L
V
D
S
L
D
P
E
T
R
R
Site 14
T179
V
D
S
L
D
P
E
T
R
R
V
A
E
L
F
Site 15
T223
S
S
T
F
L
M
G
T
N
F
P
N
K
I
E
Site 16
T243
E
H
I
R
R
N
F
T
S
A
G
D
H
I
I
Site 17
S258
I
D
G
L
H
A
E
S
P
D
D
L
V
R
E
Site 18
S287
K
C
L
E
E
L
L
S
S
R
D
L
L
A
K
Site 19
T300
A
K
L
V
G
Y
S
T
F
S
H
R
A
L
Q
Site 20
S302
L
V
G
Y
S
T
F
S
H
R
A
L
Q
G
T
Site 21
T309
S
H
R
A
L
Q
G
T
I
A
K
N
P
E
T
Site 22
T316
T
I
A
K
N
P
E
T
V
M
Q
F
L
E
K
Site 23
S325
M
Q
F
L
E
K
L
S
D
K
L
S
E
R
T
Site 24
S329
E
K
L
S
D
K
L
S
E
R
T
L
K
D
F
Site 25
Y360
V
M
P
W
D
P
P
Y
Y
S
G
V
I
R
A
Site 26
Y361
M
P
W
D
P
P
Y
Y
S
G
V
I
R
A
E
Site 27
S362
P
W
D
P
P
Y
Y
S
G
V
I
R
A
E
R
Site 28
Y403
R
L
L
G
I
S
L
Y
A
E
Q
P
A
K
G
Site 29
S414
P
A
K
G
E
V
W
S
E
D
V
R
K
L
A
Site 30
Y463
R
L
K
E
D
G
D
Y
Q
L
P
V
V
V
L
Site 31
S477
L
M
L
N
L
P
R
S
S
R
S
S
P
T
L
Site 32
S478
M
L
N
L
P
R
S
S
R
S
S
P
T
L
L
Site 33
S480
N
L
P
R
S
S
R
S
S
P
T
L
L
T
P
Site 34
S481
L
P
R
S
S
R
S
S
P
T
L
L
T
P
S
Site 35
T483
R
S
S
R
S
S
P
T
L
L
T
P
S
M
M
Site 36
T486
R
S
S
P
T
L
L
T
P
S
M
M
E
N
L
Site 37
S488
S
P
T
L
L
T
P
S
M
M
E
N
L
F
H
Site 38
Y510
S
M
L
G
R
T
R
Y
Q
H
V
T
G
T
R
Site 39
T514
R
T
R
Y
Q
H
V
T
G
T
R
C
P
T
D
Site 40
T516
R
Y
Q
H
V
T
G
T
R
C
P
T
D
F
A
Site 41
T520
V
T
G
T
R
C
P
T
D
F
A
E
V
P
S
Site 42
Y537
M
E
Y
F
A
N
D
Y
R
V
V
N
Q
F
A
Site 43
Y547
V
N
Q
F
A
R
H
Y
Q
T
G
Q
P
L
P
Site 44
S559
P
L
P
K
N
M
V
S
R
L
C
E
S
K
K
Site 45
Y586
Y
A
T
L
D
Q
I
Y
H
G
K
H
P
L
R
Site 46
S595
G
K
H
P
L
R
N
S
T
T
D
I
L
K
E
Site 47
T596
K
H
P
L
R
N
S
T
T
D
I
L
K
E
T
Site 48
Y608
K
E
T
Q
E
K
F
Y
G
L
P
Y
V
P
N
Site 49
Y612
E
K
F
Y
G
L
P
Y
V
P
N
T
A
W
Q
Site 50
T616
G
L
P
Y
V
P
N
T
A
W
Q
L
R
F
S
Site 51
Y628
R
F
S
H
L
V
G
Y
G
A
R
Y
Y
S
Y
Site 52
Y632
L
V
G
Y
G
A
R
Y
Y
S
Y
L
M
S
R
Site 53
Y633
V
G
Y
G
A
R
Y
Y
S
Y
L
M
S
R
A
Site 54
S634
G
Y
G
A
R
Y
Y
S
Y
L
M
S
R
A
V
Site 55
Y635
Y
G
A
R
Y
Y
S
Y
L
M
S
R
A
V
A
Site 56
T707
D
L
D
L
D
F
E
T
F
L
M
D
S
E
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation