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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPIN2A
Full Name:
Spindlin-2A
Alias:
Spindlin-like protein 2A
Type:
Mass (Da):
29170
Number AA:
258
UniProt ID:
Q99865
International Prot ID:
IPI00018510
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0000003
GO:0007049
GO:0007276
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
Q
E
A
E
G
Q
Q
T
R
A
A
A
G
R
A
Site 2
T22
R
A
A
A
G
R
A
T
G
S
A
N
M
T
K
Site 3
S24
A
A
G
R
A
T
G
S
A
N
M
T
K
K
K
Site 4
T28
A
T
G
S
A
N
M
T
K
K
K
V
S
Q
K
Site 5
S33
N
M
T
K
K
K
V
S
Q
K
K
Q
R
G
R
Site 6
S42
K
K
Q
R
G
R
P
S
S
Q
P
R
R
N
I
Site 7
S43
K
Q
R
G
R
P
S
S
Q
P
R
R
N
I
V
Site 8
T66
K
E
G
D
E
P
I
T
Q
W
K
G
T
V
L
Site 9
Y94
Y
D
G
I
D
C
V
Y
G
L
E
L
H
R
D
Site 10
S106
H
R
D
E
R
V
L
S
L
K
I
L
S
D
R
Site 11
S116
I
L
S
D
R
V
A
S
S
H
I
S
D
A
N
Site 12
S117
L
S
D
R
V
A
S
S
H
I
S
D
A
N
L
Site 13
S120
R
V
A
S
S
H
I
S
D
A
N
L
A
N
T
Site 14
S143
M
F
E
G
E
H
G
S
K
D
E
W
R
G
M
Site 15
Y163
P
I
M
K
A
W
F
Y
I
T
Y
E
K
D
P
Site 16
Y173
Y
E
K
D
P
V
L
Y
M
Y
Q
L
L
D
D
Site 17
Y175
K
D
P
V
L
Y
M
Y
Q
L
L
D
D
Y
K
Site 18
Y181
M
Y
Q
L
L
D
D
Y
K
E
G
D
L
R
I
Site 19
S192
D
L
R
I
M
P
E
S
S
E
S
P
P
T
E
Site 20
S193
L
R
I
M
P
E
S
S
E
S
P
P
T
E
R
Site 21
S195
I
M
P
E
S
S
E
S
P
P
T
E
R
E
P
Site 22
T198
E
S
S
E
S
P
P
T
E
R
E
P
G
G
V
Site 23
Y216
L
I
G
K
H
V
E
Y
T
K
E
D
G
S
K
Site 24
T217
I
G
K
H
V
E
Y
T
K
E
D
G
S
K
R
Site 25
S222
E
Y
T
K
E
D
G
S
K
R
I
G
M
V
I
Site 26
S237
H
Q
V
E
T
K
P
S
V
Y
F
I
K
F
D
Site 27
Y239
V
E
T
K
P
S
V
Y
F
I
K
F
D
D
D
Site 28
Y250
F
D
D
D
F
H
I
Y
V
Y
D
L
V
K
K
Site 29
Y252
D
D
F
H
I
Y
V
Y
D
L
V
K
K
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation