KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TUBB4Q
Full Name:
Putative tubulin beta-4q chain
Alias:
Type:
Mass (Da):
48435
Number AA:
434
UniProt ID:
Q99867
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
A
K
F
W
E
V
I
S
D
E
H
A
I
D
S
Site 2
Y36
A
I
D
S
A
G
T
Y
H
G
D
S
H
L
Q
Site 3
S40
A
G
T
Y
H
G
D
S
H
L
Q
L
E
R
I
Site 4
Y59
H
E
A
S
G
G
R
Y
V
P
R
A
V
L
V
Site 5
T72
L
V
D
L
E
P
G
T
M
D
S
V
R
S
G
Site 6
S75
L
E
P
G
T
M
D
S
V
R
S
G
P
F
A
Site 7
T107
N
W
A
K
G
R
Y
T
E
G
A
E
L
M
E
Site 8
S115
E
G
A
E
L
M
E
S
V
M
D
V
V
R
K
Site 9
S126
V
V
R
K
E
A
E
S
C
D
C
L
Q
G
F
Site 10
S138
Q
G
F
Q
L
T
H
S
L
G
G
G
T
G
S
Site 11
S153
G
M
G
T
L
L
L
S
K
I
R
E
E
Y
P
Site 12
Y159
L
S
K
I
R
E
E
Y
P
D
R
I
I
N
T
Site 13
T166
Y
P
D
R
I
I
N
T
F
S
I
L
P
S
P
Site 14
S172
N
T
F
S
I
L
P
S
P
K
V
S
D
T
V
Site 15
S176
I
L
P
S
P
K
V
S
D
T
V
V
E
P
Y
Site 16
T178
P
S
P
K
V
S
D
T
V
V
E
P
Y
N
A
Site 17
Y183
S
D
T
V
V
E
P
Y
N
A
T
L
S
V
H
Site 18
S188
E
P
Y
N
A
T
L
S
V
H
Q
L
I
E
N
Site 19
T199
L
I
E
N
A
D
E
T
F
C
I
D
N
E
A
Site 20
S212
E
A
L
Y
D
I
C
S
R
T
L
K
L
P
T
Site 21
T219
S
R
T
L
K
L
P
T
P
T
Y
G
D
L
N
Site 22
Y222
L
K
L
P
T
P
T
Y
G
D
L
N
H
L
V
Site 23
T274
M
P
G
F
A
P
L
T
S
Q
G
S
Q
Q
Y
Site 24
S275
P
G
F
A
P
L
T
S
Q
G
S
Q
Q
Y
R
Site 25
S278
A
P
L
T
S
Q
G
S
Q
Q
Y
R
A
L
T
Site 26
T285
S
Q
Q
Y
R
A
L
T
V
A
E
L
T
Q
Q
Site 27
Y310
R
D
P
R
H
G
C
Y
L
T
A
A
A
I
F
Site 28
S339
N
I
Q
D
K
N
S
S
Y
F
A
D
W
L
P
Site 29
Y340
I
Q
D
K
N
S
S
Y
F
A
D
W
L
P
N
Site 30
T366
W
G
L
K
M
S
V
T
F
T
G
N
N
T
A
Site 31
T368
L
K
M
S
V
T
F
T
G
N
N
T
A
V
Q
Site 32
S381
V
Q
E
L
K
R
V
S
E
Q
F
T
A
T
F
Site 33
T387
V
S
E
Q
F
T
A
T
F
R
R
K
A
F
L
Site 34
Y397
R
K
A
F
L
H
W
Y
T
G
E
G
M
D
E
Site 35
Y424
L
V
S
E
Y
Q
Q
Y
Q
D
A
T
A
E
G
Site 36
T428
Y
Q
Q
Y
Q
D
A
T
A
E
G
E
G
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation