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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HAUS7
Full Name:
HAUS augmin-like complex subunit 7
Alias:
26S proteasome-associated UCH interacting protein 1; 26S proteasome-associated UCH37 interacting protein 1; 26S proteasome-associated UCH37-interacting protein 1; 3''-5'' exonuclease; HAUS augmin-like complex, subunit 7; S1769; Three prime repair exonuclease 2; TREX2; UC5IP; UCH37 interacting protein 1; UCHL5-interacting protein; UCHL5IP; UIP1; X-linked protein STS1769
Type:
Deoxyribonuclease; DNA binding protein; EC 3.1.11.2
Mass (Da):
39794
Number AA:
358
UniProt ID:
Q99871
International Prot ID:
IPI00478278
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0070652
GO:0005813
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0031996
PhosphoSite+
KinaseNET
Biological Process:
GO:0051301
GO:0051297
GO:0007067
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y25
C
G
R
G
G
D
D
Y
S
E
D
E
G
D
S
Site 2
S26
G
R
G
G
D
D
Y
S
E
D
E
G
D
S
S
Site 3
S32
Y
S
E
D
E
G
D
S
S
V
S
R
A
A
V
Site 4
S33
S
E
D
E
G
D
S
S
V
S
R
A
A
V
E
Site 5
Y57
C
P
F
L
E
G
L
Y
I
T
E
P
K
T
I
Site 6
S70
T
I
Q
E
L
L
C
S
P
S
E
Y
R
L
E
Site 7
S72
Q
E
L
L
C
S
P
S
E
Y
R
L
E
I
L
Site 8
Y74
L
L
C
S
P
S
E
Y
R
L
E
I
L
E
W
Site 9
S89
M
C
T
R
V
W
P
S
L
Q
D
R
F
S
S
Site 10
S95
P
S
L
Q
D
R
F
S
S
L
K
G
V
P
T
Site 11
S96
S
L
Q
D
R
F
S
S
L
K
G
V
P
T
E
Site 12
T102
S
S
L
K
G
V
P
T
E
V
K
I
Q
E
M
Site 13
S149
Q
L
L
D
T
I
R
S
L
T
I
G
C
S
S
Site 14
S159
I
G
C
S
S
C
S
S
L
M
E
H
F
E
D
Site 15
S214
S
D
D
W
Q
W
A
S
A
S
A
K
S
E
E
Site 16
S235
L
A
R
Q
L
Q
E
S
A
A
K
L
H
A
L
Site 17
T244
A
K
L
H
A
L
R
T
E
Y
F
A
Q
H
E
Site 18
Y246
L
H
A
L
R
T
E
Y
F
A
Q
H
E
Q
G
Site 19
S262
A
A
G
A
A
D
I
S
T
L
D
Q
K
L
R
Site 20
T263
A
G
A
A
D
I
S
T
L
D
Q
K
L
R
L
Site 21
T272
D
Q
K
L
R
L
V
T
S
D
F
H
Q
L
I
Site 22
T311
C
G
P
I
I
Q
A
T
H
Q
N
L
T
S
Y
Site 23
S317
A
T
H
Q
N
L
T
S
Y
S
Q
L
L
Q
V
Site 24
S354
I
C
W
G
G
S
S
S
V
M
S
L
A
T
K
Site 25
S357
G
G
S
S
S
V
M
S
L
A
T
K
M
N
E
Site 26
T360
S
S
V
M
S
L
A
T
K
M
N
E
L
M
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation