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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRMT1
Full Name:
Protein arginine N-methyltransferase 1
Alias:
HMT2; HRMT1L2; Interferon receptor 1-bound protein 4; IR1B4
Type:
Methyltransferase
Mass (Da):
41516
Number AA:
361
UniProt ID:
Q99873
International Prot ID:
IPI00215734
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006464
GO:0006479
GO:0006730
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
A
T
L
A
N
G
M
S
L
Q
P
P
L
E
E
Site 2
S39
P
N
A
E
D
M
T
S
K
D
Y
Y
F
D
S
Site 3
Y42
E
D
M
T
S
K
D
Y
Y
F
D
S
Y
A
H
Site 4
Y43
D
M
T
S
K
D
Y
Y
F
D
S
Y
A
H
F
Site 5
Y47
K
D
Y
Y
F
D
S
Y
A
H
F
G
I
H
E
Site 6
T65
K
D
E
V
R
T
L
T
Y
R
N
S
M
F
H
Site 7
T166
F
Y
E
S
M
L
N
T
V
L
Y
A
R
D
K
Site 8
Y189
F
P
D
R
A
T
L
Y
V
T
A
I
E
D
R
Site 9
Y198
T
A
I
E
D
R
Q
Y
K
D
Y
K
I
H
W
Site 10
T237
V
D
P
K
Q
L
V
T
N
A
C
L
I
K
E
Site 11
Y270
L
Q
V
K
R
N
D
Y
V
H
A
L
V
A
Y
Site 12
T289
F
T
R
C
H
K
R
T
G
F
S
T
S
P
E
Site 13
S292
C
H
K
R
T
G
F
S
T
S
P
E
S
P
Y
Site 14
T293
H
K
R
T
G
F
S
T
S
P
E
S
P
Y
T
Site 15
S294
K
R
T
G
F
S
T
S
P
E
S
P
Y
T
H
Site 16
S297
G
F
S
T
S
P
E
S
P
Y
T
H
W
K
Q
Site 17
Y299
S
T
S
P
E
S
P
Y
T
H
W
K
Q
T
V
Site 18
T300
T
S
P
E
S
P
Y
T
H
W
K
Q
T
V
F
Site 19
T305
P
Y
T
H
W
K
Q
T
V
F
Y
M
E
D
Y
Site 20
Y312
T
V
F
Y
M
E
D
Y
L
T
V
K
T
G
E
Site 21
T314
F
Y
M
E
D
Y
L
T
V
K
T
G
E
E
I
Site 22
T324
T
G
E
E
I
F
G
T
I
G
M
R
P
N
A
Site 23
T340
N
N
R
D
L
D
F
T
I
D
L
D
F
K
G
Site 24
S353
K
G
Q
L
C
E
L
S
C
S
T
D
Y
R
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation