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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPAG8
Full Name:
Sperm-associated antigen 8
Alias:
HSD-1;Sperm membrane protein 1;Sperm membrane protein BS-84
Type:
Mass (Da):
44819
Number AA:
426
UniProt ID:
Q99932
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
E
T
N
E
S
T
E
G
S
R
S
R
Site 2
S10
T
N
E
S
T
E
G
S
R
S
R
S
R
S
L
Site 3
S12
E
S
T
E
G
S
R
S
R
S
R
S
L
D
I
Site 4
S14
T
E
G
S
R
S
R
S
R
S
L
D
I
Q
P
Site 5
S16
G
S
R
S
R
S
R
S
L
D
I
Q
P
S
S
Site 6
S22
R
S
L
D
I
Q
P
S
S
E
G
L
G
P
T
Site 7
S23
S
L
D
I
Q
P
S
S
E
G
L
G
P
T
S
Site 8
T29
S
S
E
G
L
G
P
T
S
E
P
F
P
S
S
Site 9
S30
S
E
G
L
G
P
T
S
E
P
F
P
S
S
D
Site 10
S35
P
T
S
E
P
F
P
S
S
D
D
S
P
R
S
Site 11
S36
T
S
E
P
F
P
S
S
D
D
S
P
R
S
A
Site 12
S39
P
F
P
S
S
D
D
S
P
R
S
A
L
A
A
Site 13
S42
S
S
D
D
S
P
R
S
A
L
A
A
A
T
A
Site 14
T74
A
K
A
A
A
L
S
T
K
T
P
A
P
C
S
Site 15
S81
T
K
T
P
A
P
C
S
E
F
M
E
P
S
S
Site 16
S87
C
S
E
F
M
E
P
S
S
D
P
S
L
L
G
Site 17
S88
S
E
F
M
E
P
S
S
D
P
S
L
L
G
E
Site 18
S91
M
E
P
S
S
D
P
S
L
L
G
E
P
C
A
Site 19
S110
T
H
N
I
A
H
G
S
L
G
F
E
P
V
Y
Site 20
T125
V
S
C
I
A
Q
D
T
C
T
T
T
D
H
S
Site 21
T127
C
I
A
Q
D
T
C
T
T
T
D
H
S
S
N
Site 22
T129
A
Q
D
T
C
T
T
T
D
H
S
S
N
P
G
Site 23
S132
T
C
T
T
T
D
H
S
S
N
P
G
P
V
P
Site 24
S133
C
T
T
T
D
H
S
S
N
P
G
P
V
P
G
Site 25
S141
N
P
G
P
V
P
G
S
S
S
G
P
V
L
G
Site 26
S142
P
G
P
V
P
G
S
S
S
G
P
V
L
G
S
Site 27
S143
G
P
V
P
G
S
S
S
G
P
V
L
G
S
S
Site 28
S149
S
S
G
P
V
L
G
S
S
S
G
A
G
H
G
Site 29
S150
S
G
P
V
L
G
S
S
S
G
A
G
H
G
S
Site 30
S151
G
P
V
L
G
S
S
S
G
A
G
H
G
S
G
Site 31
S157
S
S
G
A
G
H
G
S
G
S
G
S
G
P
G
Site 32
S159
G
A
G
H
G
S
G
S
G
S
G
P
G
C
G
Site 33
S161
G
H
G
S
G
S
G
S
G
P
G
C
G
S
V
Site 34
S167
G
S
G
P
G
C
G
S
V
P
G
S
G
S
G
Site 35
S171
G
C
G
S
V
P
G
S
G
S
G
P
G
P
G
Site 36
S173
G
S
V
P
G
S
G
S
G
P
G
P
G
S
G
Site 37
S179
G
S
G
P
G
P
G
S
G
P
G
S
G
P
G
Site 38
S183
G
P
G
S
G
P
G
S
G
P
G
H
G
S
G
Site 39
S189
G
S
G
P
G
H
G
S
G
S
H
P
G
P
A
Site 40
S191
G
P
G
H
G
S
G
S
H
P
G
P
A
S
G
Site 41
S197
G
S
H
P
G
P
A
S
G
P
G
P
D
T
G
Site 42
T203
A
S
G
P
G
P
D
T
G
P
D
S
E
L
S
Site 43
S207
G
P
D
T
G
P
D
S
E
L
S
P
C
I
P
Site 44
S210
T
G
P
D
S
E
L
S
P
C
I
P
P
G
F
Site 45
Y228
V
A
D
R
V
P
N
Y
T
S
W
S
Q
H
C
Site 46
Y272
K
G
K
L
M
V
C
Y
E
T
L
P
R
G
Q
Site 47
Y283
P
R
G
Q
C
L
L
Y
N
W
E
E
E
R
A
Site 48
S299
N
H
L
D
Q
V
P
S
M
Q
D
G
S
E
S
Site 49
S304
V
P
S
M
Q
D
G
S
E
S
F
F
F
R
H
Site 50
S306
S
M
Q
D
G
S
E
S
F
F
F
R
H
G
H
Site 51
T318
H
G
H
R
G
L
L
T
M
Q
L
K
S
P
M
Site 52
S323
L
L
T
M
Q
L
K
S
P
M
P
S
S
T
T
Site 53
S327
Q
L
K
S
P
M
P
S
S
T
T
Q
K
D
S
Site 54
S328
L
K
S
P
M
P
S
S
T
T
Q
K
D
S
Y
Site 55
T329
K
S
P
M
P
S
S
T
T
Q
K
D
S
Y
Q
Site 56
T330
S
P
M
P
S
S
T
T
Q
K
D
S
Y
Q
P
Site 57
S334
S
S
T
T
Q
K
D
S
Y
Q
P
P
G
N
V
Site 58
Y335
S
T
T
Q
K
D
S
Y
Q
P
P
G
N
V
Y
Site 59
Y342
Y
Q
P
P
G
N
V
Y
W
P
L
R
G
K
R
Site 60
S380
R
K
L
F
E
V
E
S
V
T
H
H
D
Y
R
Site 61
Y386
E
S
V
T
H
H
D
Y
R
M
E
L
A
Q
A
Site 62
T395
M
E
L
A
Q
A
G
T
P
A
P
T
K
P
H
Site 63
Y404
A
P
T
K
P
H
D
Y
R
Q
E
Q
P
E
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation