PhosphoNET

           
Protein Info 
   
Short Name:  DUSP9
Full Name:  Dual specificity protein phosphatase 9
Alias:  DUS9; EC 3.1.3.16; EC 3.1.3.48; Mitogen-activated protein kinase phosphatase 4; MKP4
Type:  Protein phosphatase, dual specificity
Mass (Da):  41868
Number AA:  384
UniProt ID:  Q99956
International Prot ID:  IPI00294486
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005783  GO:0005634  GO:0005783 Uniprot OncoNet
Molecular Function:  GO:0004725  GO:0004721  GO:0004725 PhosphoSite+ KinaseNET
Biological Process:  GO:0007254  GO:0000188  GO:0006470 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S16LWLRRELSPPRPRLL
Site 2S29LLLLDCRSRELYESA
Site 3Y33DCRSRELYESARIGG
Site 4S35RSRELYESARIGGAL
Site 5S58LRRLRRGSLSVRALL
Site 6S60RLRRGSLSVRALLPG
Site 7Y81PPAPVLLYDQGGGRR
Site 8T108EAESVLGTLLQKLRE
Site 9Y118QKLREEGYLAYYLQG
Site 10Y121REEGYLAYYLQGGFS
Site 11Y122EEGYLAYYLQGGFSR
Site 12S169LGSLCLGSDCSDAES
Site 13S172LCLGSDCSDAESEAD
Site 14S176SDCSDAESEADRDSM
Site 15S182ESEADRDSMSCGLDS
Site 16S184EADRDSMSCGLDSEG
Site 17S189SMSCGLDSEGATPPP
Site 18T193GLDSEGATPPPVGLR
Site 19S215LPNLYLGSARDSANL
Site 20S219YLGSARDSANLESLA
Site 21S224RDSANLESLAKLGIR
Site 22Y232LAKLGIRYILNVTPN
Site 23T237IRYILNVTPNLPNFF
Site 24Y252EKNGDFHYKQIPISD
Site 25S312LMQKLHLSLNDAYDL
Site 26Y317HLSLNDAYDLVKRKK
Site 27S325DLVKRKKSNISPNFN
Site 28S328KRKKSNISPNFNFMG
Site 29S343QLLDFERSLRLEERH
Site 30S351LRLEERHSQEQGSGG
Site 31S356RHSQEQGSGGQASAA
Site 32S361QGSGGQASAASNPPS
Site 33S364GGQASAASNPPSFFT
Site 34S368SAASNPPSFFTTPTS
Site 35T371SNPPSFFTTPTSDGA
Site 36T372NPPSFFTTPTSDGAF
Site 37T374PSFFTTPTSDGAFEL
Site 38S375SFFTTPTSDGAFELA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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