KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SH3GL2
Full Name:
Endophilin-A1
Alias:
CNSA2; EEN-B1; SH3 domain protein 2A; SH3-containing GRB2-like protein 2; SH3D2A; SH3-domain GRB2-like 2; SH3G2; SH3P4
Type:
EC 2.3.1.-; Transferase; Vesicle protein; Adaptor/scaffold
Mass (Da):
39962
Number AA:
352
UniProt ID:
Q99962
International Prot ID:
IPI00019171
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0019898
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0042802
GO:0008289
PhosphoSite+
KinaseNET
Biological Process:
GO:0007417
GO:0006897
GO:0006892
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
K
K
Q
F
H
K
A
T
Q
K
V
S
E
K
V
Site 2
T43
M
E
R
K
V
D
V
T
S
R
A
V
M
E
I
Site 3
S44
E
R
K
V
D
V
T
S
R
A
V
M
E
I
M
Site 4
Y57
I
M
T
K
T
I
E
Y
L
Q
P
N
P
A
S
Site 5
S64
Y
L
Q
P
N
P
A
S
R
A
K
L
S
M
I
Site 6
S69
P
A
S
R
A
K
L
S
M
I
N
T
M
S
K
Site 7
T73
A
K
L
S
M
I
N
T
M
S
K
I
R
G
Q
Site 8
S75
L
S
M
I
N
T
M
S
K
I
R
G
Q
E
K
Site 9
Y86
G
Q
E
K
G
P
G
Y
P
Q
A
E
A
L
L
Site 10
S125
G
E
A
M
R
E
L
S
E
V
K
D
S
L
D
Site 11
S130
E
L
S
E
V
K
D
S
L
D
I
E
V
K
Q
Site 12
Y170
G
R
R
L
D
F
D
Y
K
K
K
R
Q
G
K
Site 13
S199
E
S
K
E
I
A
E
S
S
M
F
N
L
L
E
Site 14
S200
S
K
E
I
A
E
S
S
M
F
N
L
L
E
M
Site 15
S213
E
M
D
I
E
Q
V
S
Q
L
S
A
L
V
Q
Site 16
S248
E
E
R
I
R
Q
A
S
S
Q
P
R
R
E
Y
Site 17
S249
E
R
I
R
Q
A
S
S
Q
P
R
R
E
Y
Q
Site 18
Y255
S
S
Q
P
R
R
E
Y
Q
P
K
P
R
M
S
Site 19
S262
Y
Q
P
K
P
R
M
S
L
E
F
P
T
G
D
Site 20
S270
L
E
F
P
T
G
D
S
T
Q
P
N
G
G
L
Site 21
T271
E
F
P
T
G
D
S
T
Q
P
N
G
G
L
S
Site 22
S278
T
Q
P
N
G
G
L
S
H
T
G
T
P
K
P
Site 23
T280
P
N
G
G
L
S
H
T
G
T
P
K
P
S
G
Site 24
T282
G
G
L
S
H
T
G
T
P
K
P
S
G
V
Q
Site 25
Y299
Q
P
C
C
R
A
L
Y
D
F
E
P
E
N
E
Site 26
Y328
N
Q
I
D
E
N
W
Y
E
G
M
L
H
G
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation