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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SH3GL3
Full Name:
Endophilin-A3
Alias:
CNSA3; EEN-2B-L3; EEN-B2; Endophilin-3; SH3G3
Type:
Membrane, Endosome, Early endosome membrane, Cytoplasm protein
Mass (Da):
39285
Number AA:
347
UniProt ID:
Q99963
International Prot ID:
IPI00019172
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005768
GO:0019898
Uniprot
OncoNet
Molecular Function:
GO:0042802
GO:0008289
PhosphoSite+
KinaseNET
Biological Process:
GO:0007417
GO:0006897
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
K
K
Q
F
H
K
A
S
Q
L
F
S
E
K
I
Site 2
S18
H
K
A
S
Q
L
F
S
E
K
I
S
G
A
E
Site 3
S22
Q
L
F
S
E
K
I
S
G
A
E
G
T
K
L
Site 4
T43
M
E
R
K
I
D
V
T
N
K
V
V
A
E
I
Site 5
Y57
I
L
S
K
T
T
E
Y
L
Q
P
N
P
A
Y
Site 6
Y64
Y
L
Q
P
N
P
A
Y
R
A
K
L
G
M
L
Site 7
T73
A
K
L
G
M
L
N
T
V
S
K
I
R
G
Q
Site 8
S75
L
G
M
L
N
T
V
S
K
I
R
G
Q
V
K
Site 9
T83
K
I
R
G
Q
V
K
T
T
G
Y
P
Q
T
E
Site 10
Y86
G
Q
V
K
T
T
G
Y
P
Q
T
E
G
L
L
Site 11
Y100
L
G
D
C
M
L
K
Y
G
K
E
L
G
E
D
Site 12
T109
K
E
L
G
E
D
S
T
F
G
N
A
L
I
E
Site 13
S130
L
M
A
E
V
K
D
S
L
D
I
N
V
K
Q
Site 14
Y168
L
E
G
R
R
L
D
Y
D
Y
K
K
K
R
V
Site 15
Y170
G
R
R
L
D
Y
D
Y
K
K
K
R
V
G
K
Site 16
S200
S
K
E
L
A
E
R
S
M
F
N
F
L
E
N
Site 17
Y225
F
I
E
A
A
L
D
Y
H
R
Q
S
T
E
I
Site 18
S229
A
L
D
Y
H
R
Q
S
T
E
I
L
Q
E
L
Site 19
T230
L
D
Y
H
R
Q
S
T
E
I
L
Q
E
L
Q
Site 20
S238
E
I
L
Q
E
L
Q
S
K
L
Q
M
R
I
S
Site 21
S245
S
K
L
Q
M
R
I
S
A
A
S
S
V
P
R
Site 22
S248
Q
M
R
I
S
A
A
S
S
V
P
R
R
E
Y
Site 23
S249
M
R
I
S
A
A
S
S
V
P
R
R
E
Y
K
Site 24
Y255
S
S
V
P
R
R
E
Y
K
P
R
P
V
K
R
Site 25
S263
K
P
R
P
V
K
R
S
S
S
E
L
N
G
V
Site 26
S264
P
R
P
V
K
R
S
S
S
E
L
N
G
V
S
Site 27
S265
R
P
V
K
R
S
S
S
E
L
N
G
V
S
T
Site 28
S271
S
S
E
L
N
G
V
S
T
T
S
V
V
K
T
Site 29
T278
S
T
T
S
V
V
K
T
T
G
S
N
I
P
M
Site 30
Y294
Q
P
C
C
R
G
L
Y
D
F
E
P
E
N
Q
Site 31
Y323
N
Q
I
D
E
N
W
Y
E
G
M
I
H
G
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation