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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADAM2
Full Name:
Disintegrin and metalloproteinase domain-containing protein 2
Alias:
Cancer/testis antigen 15;Fertilin subunit beta;PH-30;PH30-beta
Type:
Mass (Da):
82457
Number AA:
735
UniProt ID:
Q99965
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
L
G
G
L
R
M
D
S
N
F
D
S
L
P
V
Site 2
S22
R
M
D
S
N
F
D
S
L
P
V
Q
I
T
V
Site 3
T28
D
S
L
P
V
Q
I
T
V
P
E
K
I
R
S
Site 4
S35
T
V
P
E
K
I
R
S
I
I
K
E
G
I
E
Site 5
S46
E
G
I
E
S
Q
A
S
Y
K
I
V
I
E
G
Site 6
Y47
G
I
E
S
Q
A
S
Y
K
I
V
I
E
G
K
Site 7
T57
V
I
E
G
K
P
Y
T
V
N
L
M
Q
K
N
Site 8
Y73
L
P
H
N
F
R
V
Y
S
Y
S
G
T
G
I
Site 9
S74
P
H
N
F
R
V
Y
S
Y
S
G
T
G
I
M
Site 10
S76
N
F
R
V
Y
S
Y
S
G
T
G
I
M
K
P
Site 11
T78
R
V
Y
S
Y
S
G
T
G
I
M
K
P
L
D
Site 12
Y97
N
F
C
H
Y
Q
G
Y
I
E
G
Y
P
K
S
Site 13
Y101
Y
Q
G
Y
I
E
G
Y
P
K
S
V
V
M
V
Site 14
Y125
L
Q
F
E
N
V
S
Y
G
I
E
P
L
E
S
Site 15
S132
Y
G
I
E
P
L
E
S
S
V
G
F
E
H
V
Site 16
Y141
V
G
F
E
H
V
I
Y
Q
V
K
H
K
K
A
Site 17
S151
K
H
K
K
A
D
V
S
L
Y
N
E
K
D
I
Site 18
Y153
K
K
A
D
V
S
L
Y
N
E
K
D
I
E
S
Site 19
S164
D
I
E
S
R
D
L
S
F
K
L
Q
S
V
E
Site 20
S169
D
L
S
F
K
L
Q
S
V
E
P
Q
Q
D
F
Site 21
T718
F
Q
R
K
K
W
R
T
E
D
Y
S
S
D
E
Site 22
Y721
K
K
W
R
T
E
D
Y
S
S
D
E
Q
P
E
Site 23
S722
K
W
R
T
E
D
Y
S
S
D
E
Q
P
E
S
Site 24
S723
W
R
T
E
D
Y
S
S
D
E
Q
P
E
S
E
Site 25
S729
S
S
D
E
Q
P
E
S
E
S
E
P
K
G
_
Site 26
S731
D
E
Q
P
E
S
E
S
E
P
K
G
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation