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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DPYSL5
Full Name:
Dihydropyrimidinase-related protein 5
Alias:
Collapsin response mediator protein 5; CRAM; CRMP5; CRMP-5; DPYL5; FLJ45383; Ulip6; ULIP6 protein
Type:
Mass (Da):
61421
Number AA:
564
UniProt ID:
Q9BPU6
International Prot ID:
IPI00335509
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0016810
PhosphoSite+
KinaseNET
Biological Process:
GO:0007411
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y29
C
T
H
E
A
D
V
Y
I
E
N
G
I
I
Q
Site 2
T65
V
I
P
G
G
I
D
T
S
T
H
F
H
Q
T
Site 3
Y113
E
T
S
L
V
D
A
Y
E
K
C
R
G
L
A
Site 4
Y163
S
F
Q
M
F
M
T
Y
K
D
L
Y
M
L
R
Site 5
Y167
F
M
T
Y
K
D
L
Y
M
L
R
D
S
E
L
Site 6
S172
D
L
Y
M
L
R
D
S
E
L
Y
Q
V
L
H
Site 7
Y175
M
L
R
D
S
E
L
Y
Q
V
L
H
A
C
K
Site 8
S219
G
P
E
G
I
E
I
S
R
P
E
E
L
E
A
Site 9
T229
E
E
L
E
A
E
A
T
H
R
V
I
T
I
A
Site 10
T234
E
A
T
H
R
V
I
T
I
A
N
R
T
H
C
Site 11
T277
E
T
T
T
A
H
A
T
L
T
G
L
H
Y
Y
Site 12
Y294
D
W
S
H
A
A
A
Y
V
T
V
P
P
L
R
Site 13
T304
V
P
P
L
R
L
D
T
N
T
S
T
Y
L
M
Site 14
T306
P
L
R
L
D
T
N
T
S
T
Y
L
M
S
L
Site 15
T318
M
S
L
L
A
N
D
T
L
N
I
V
A
S
D
Site 16
S324
D
T
L
N
I
V
A
S
D
H
R
P
F
T
T
Site 17
T330
A
S
D
H
R
P
F
T
T
K
Q
K
A
M
G
Site 18
T342
A
M
G
K
E
D
F
T
K
I
P
H
G
V
S
Site 19
S356
S
G
V
Q
D
R
M
S
V
I
W
E
R
G
V
Site 20
T377
E
N
R
F
V
A
V
T
S
S
N
A
A
K
L
Site 21
Y388
A
A
K
L
L
N
L
Y
P
R
K
G
R
I
I
Site 22
T412
W
D
P
E
A
T
K
T
I
S
A
S
T
Q
V
Site 23
S414
P
E
A
T
K
T
I
S
A
S
T
Q
V
Q
G
Site 24
S416
A
T
K
T
I
S
A
S
T
Q
V
Q
G
G
D
Site 25
Y427
Q
G
G
D
F
N
L
Y
E
N
M
R
C
H
G
Site 26
S466
G
K
F
C
P
L
R
S
F
P
D
T
V
Y
K
Site 27
T470
P
L
R
S
F
P
D
T
V
Y
K
K
L
V
Q
Site 28
Y472
R
S
F
P
D
T
V
Y
K
K
L
V
Q
R
E
Site 29
T481
K
L
V
Q
R
E
K
T
L
K
V
R
G
V
D
Site 30
T490
K
V
R
G
V
D
R
T
P
Y
L
G
D
V
A
Site 31
T509
P
G
K
K
E
M
G
T
P
L
A
D
T
P
T
Site 32
T514
M
G
T
P
L
A
D
T
P
T
R
P
V
T
R
Site 33
T516
T
P
L
A
D
T
P
T
R
P
V
T
R
H
G
Site 34
T520
D
T
P
T
R
P
V
T
R
H
G
G
M
R
D
Site 35
S531
G
M
R
D
L
H
E
S
S
F
S
L
S
G
S
Site 36
S532
M
R
D
L
H
E
S
S
F
S
L
S
G
S
Q
Site 37
S534
D
L
H
E
S
S
F
S
L
S
G
S
Q
I
D
Site 38
S536
H
E
S
S
F
S
L
S
G
S
Q
I
D
D
H
Site 39
S538
S
S
F
S
L
S
G
S
Q
I
D
D
H
V
P
Site 40
S549
D
H
V
P
K
R
A
S
A
R
I
L
A
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation