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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GRWD1
Full Name:
Glutamate-rich WD repeat-containing protein 1
Alias:
glutamate-rich WD repeat containing 1; GRWD; KIAA1942; regulator of ribosome biogenesis 1; RRB1; WDR28
Type:
RNA binding protein
Mass (Da):
49419
Number AA:
446
UniProt ID:
Q9BQ67
International Prot ID:
IPI00027831
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
A
R
K
G
R
R
R
T
C
E
T
G
E
P
M
Site 2
T13
G
R
R
R
T
C
E
T
G
E
P
M
E
A
E
Site 3
S21
G
E
P
M
E
A
E
S
G
D
T
S
S
E
G
Site 4
T24
M
E
A
E
S
G
D
T
S
S
E
G
P
A
Q
Site 5
S25
E
A
E
S
G
D
T
S
S
E
G
P
A
Q
V
Site 6
S26
A
E
S
G
D
T
S
S
E
G
P
A
Q
V
Y
Site 7
Y33
S
E
G
P
A
Q
V
Y
L
P
G
R
G
P
P
Site 8
Y54
L
V
M
D
E
E
A
Y
V
L
Y
H
R
A
Q
Site 9
Y57
D
E
E
A
Y
V
L
Y
H
R
A
Q
T
G
A
Site 10
S68
Q
T
G
A
P
C
L
S
F
D
I
V
R
D
H
Site 11
T81
D
H
L
G
D
N
R
T
E
L
P
L
T
L
Y
Site 12
S100
T
Q
A
E
S
A
Q
S
N
R
L
M
M
L
R
Site 13
T114
R
M
H
N
L
H
G
T
K
P
P
P
S
E
G
Site 14
S119
H
G
T
K
P
P
P
S
E
G
S
D
E
E
E
Site 15
S122
K
P
P
P
S
E
G
S
D
E
E
E
E
E
E
Site 16
Y149
E
L
A
M
V
P
H
Y
G
G
I
N
R
V
R
Site 17
S158
G
I
N
R
V
R
V
S
W
L
G
E
E
P
V
Site 18
S223
E
G
F
A
L
D
W
S
P
R
V
T
G
R
L
Site 19
T227
L
D
W
S
P
R
V
T
G
R
L
L
T
G
D
Site 20
T232
R
V
T
G
R
L
L
T
G
D
C
Q
K
N
I
Site 21
T243
Q
K
N
I
H
L
W
T
P
T
D
G
G
S
W
Site 22
S263
P
F
V
G
H
T
R
S
V
E
D
L
Q
W
S
Site 23
S270
S
V
E
D
L
Q
W
S
P
T
E
N
T
V
F
Site 24
T275
Q
W
S
P
T
E
N
T
V
F
A
S
C
S
A
Site 25
S285
A
S
C
S
A
D
A
S
I
R
I
W
D
I
R
Site 26
S315
D
G
D
V
N
V
I
S
W
S
R
R
E
P
F
Site 27
S317
D
V
N
V
I
S
W
S
R
R
E
P
F
L
L
Site 28
S325
R
R
E
P
F
L
L
S
G
G
D
D
G
A
L
Site 29
S342
W
D
L
R
Q
F
K
S
G
S
P
V
A
T
F
Site 30
S344
L
R
Q
F
K
S
G
S
P
V
A
T
F
K
Q
Site 31
T348
K
S
G
S
P
V
A
T
F
K
Q
H
V
A
P
Site 32
S366
V
E
W
H
P
Q
D
S
G
V
F
A
A
S
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation