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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ECSIT
Full Name:
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
Alias:
Protein SITPEC
Type:
Mass (Da):
49148
Number AA:
431
UniProt ID:
Q9BQ95
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
A
L
T
G
T
S
I
S
Q
V
P
R
R
L
P
Site 2
S44
L
P
R
G
L
H
C
S
A
A
A
H
S
S
E
Site 3
S49
H
C
S
A
A
A
H
S
S
E
Q
S
L
V
P
Site 4
S50
C
S
A
A
A
H
S
S
E
Q
S
L
V
P
S
Site 5
S53
A
A
H
S
S
E
Q
S
L
V
P
S
P
P
E
Site 6
S57
S
E
Q
S
L
V
P
S
P
P
E
P
R
Q
R
Site 7
T66
P
E
P
R
Q
R
P
T
K
A
L
V
P
F
E
Site 8
S88
G
G
E
R
D
K
A
S
F
L
Q
T
V
Q
K
Site 9
T92
D
K
A
S
F
L
Q
T
V
Q
K
F
A
E
H
Site 10
S100
V
Q
K
F
A
E
H
S
V
R
K
R
G
H
I
Site 11
Y111
R
G
H
I
D
F
I
Y
L
A
L
R
K
M
R
Site 12
Y120
A
L
R
K
M
R
E
Y
G
V
E
R
D
L
A
Site 13
Y154
I
Q
R
I
F
V
H
Y
P
R
Q
Q
E
C
G
Site 14
Y192
Q
I
F
G
R
K
S
Y
P
M
L
K
L
V
R
Site 15
S239
R
H
M
E
P
D
L
S
A
R
V
T
I
Y
Q
Site 16
Y245
L
S
A
R
V
T
I
Y
Q
V
P
L
P
K
D
Site 17
T254
V
P
L
P
K
D
S
T
G
A
A
D
P
P
Q
Site 18
S269
P
H
I
V
G
I
Q
S
P
D
Q
Q
A
A
L
Site 19
Y301
W
L
R
N
K
C
V
Y
Y
H
I
L
R
A
D
Site 20
T320
E
E
R
E
V
E
E
T
P
E
E
W
N
L
Y
Site 21
Y327
T
P
E
E
W
N
L
Y
Y
P
M
Q
L
D
L
Site 22
Y328
P
E
E
W
N
L
Y
Y
P
M
Q
L
D
L
E
Site 23
Y336
P
M
Q
L
D
L
E
Y
V
R
S
G
W
D
N
Site 24
Y344
V
R
S
G
W
D
N
Y
E
F
D
I
N
E
V
Site 25
S396
V
V
F
R
L
A
G
S
T
R
E
L
Q
T
S
Site 26
T397
V
F
R
L
A
G
S
T
R
E
L
Q
T
S
S
Site 27
S403
S
T
R
E
L
Q
T
S
S
A
G
L
E
E
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation