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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR77
Full Name:
Methylosome protein 50
Alias:
HKMT1069; MEP50; MGC2722; Nbla10071; RP11-552M11.3; WD repeat domain 77
Type:
Nuclear receptor co-regulator
Mass (Da):
36724
Number AA:
342
UniProt ID:
Q9BQA1
International Prot ID:
IPI00012202
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0030374
PhosphoSite+
KinaseNET
Biological Process:
GO:0000387
GO:0009987
GO:0016043
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T5
_
_
_
M
R
K
E
T
P
P
P
L
V
P
P
Site 2
Y36
R
Q
L
E
A
A
R
Y
R
S
D
G
A
L
L
Site 3
S74
A
P
N
E
G
F
C
S
A
G
V
Q
T
E
A
Site 4
T113
W
E
L
D
E
N
E
T
L
I
V
S
K
F
C
Site 5
Y122
I
V
S
K
F
C
K
Y
E
H
D
D
I
V
S
Site 6
S129
Y
E
H
D
D
I
V
S
T
V
S
V
L
S
S
Site 7
T130
E
H
D
D
I
V
S
T
V
S
V
L
S
S
G
Site 8
S142
S
S
G
T
Q
A
V
S
G
S
K
D
I
C
I
Site 9
S162
A
Q
Q
V
V
L
S
S
Y
R
A
H
A
A
Q
Site 10
S181
A
A
S
P
H
K
D
S
V
F
L
S
C
S
E
Site 11
S185
H
K
D
S
V
F
L
S
C
S
E
D
N
R
I
Site 12
T197
N
R
I
L
L
W
D
T
R
C
P
K
P
A
S
Site 13
S204
T
R
C
P
K
P
A
S
Q
I
G
C
S
A
P
Site 14
S217
A
P
G
Y
L
P
T
S
L
A
W
H
P
Q
Q
Site 15
S238
G
D
E
N
G
T
V
S
L
V
D
T
K
S
T
Site 16
S250
K
S
T
S
C
V
L
S
S
A
V
H
S
Q
C
Site 17
S264
C
V
T
G
L
V
F
S
P
H
S
V
P
F
L
Site 18
S293
S
L
S
E
L
F
R
S
Q
A
H
R
D
F
V
Site 19
T304
R
D
F
V
R
D
A
T
W
S
P
L
N
H
S
Site 20
S306
F
V
R
D
A
T
W
S
P
L
N
H
S
L
L
Site 21
S311
T
W
S
P
L
N
H
S
L
L
T
T
V
G
W
Site 22
T314
P
L
N
H
S
L
L
T
T
V
G
W
D
H
Q
Site 23
T315
L
N
H
S
L
L
T
T
V
G
W
D
H
Q
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation