KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SYT3
Full Name:
Synaptotagmin-3
Alias:
Synaptotagmin III; SytIII
Type:
Vesicle protein; Calcium-binding protein
Mass (Da):
63304
Number AA:
590
UniProt ID:
Q9BQG1
International Prot ID:
IPI00031100
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0005768
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Synaptotagmin-3 pan-specific antibody AB-NN366-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN366-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T29
A
R
V
R
D
A
D
T
N
D
R
C
Q
E
F
Site 2
Y43
F
N
D
R
I
R
G
Y
P
R
G
P
D
A
D
Site 3
S89
P
W
R
D
K
G
G
S
A
V
G
G
G
P
L
Site 4
S150
A
E
L
L
E
P
G
S
L
G
G
S
D
T
P
Site 5
S154
E
P
G
S
L
G
G
S
D
T
P
E
P
S
Y
Site 6
T156
G
S
L
G
G
S
D
T
P
E
P
S
Y
L
D
Site 7
S160
G
S
D
T
P
E
P
S
Y
L
D
M
D
S
Y
Site 8
Y161
S
D
T
P
E
P
S
Y
L
D
M
D
S
Y
P
Site 9
S166
P
S
Y
L
D
M
D
S
Y
P
E
A
A
A
A
Site 10
Y167
S
Y
L
D
M
D
S
Y
P
E
A
A
A
A
A
Site 11
T184
A
G
V
K
P
S
Q
T
S
P
E
L
P
S
E
Site 12
S185
G
V
K
P
S
Q
T
S
P
E
L
P
S
E
G
Site 13
S190
Q
T
S
P
E
L
P
S
E
G
G
A
G
S
G
Site 14
S210
P
S
G
G
G
L
P
S
A
Q
S
H
Q
Q
V
Site 15
S213
G
G
L
P
S
A
Q
S
H
Q
Q
V
T
S
L
Site 16
S219
Q
S
H
Q
Q
V
T
S
L
A
P
T
T
R
Y
Site 17
T223
Q
V
T
S
L
A
P
T
T
R
Y
P
A
L
P
Site 18
T224
V
T
S
L
A
P
T
T
R
Y
P
A
L
P
R
Site 19
Y226
S
L
A
P
T
T
R
Y
P
A
L
P
R
P
L
Site 20
T234
P
A
L
P
R
P
L
T
Q
Q
T
L
T
S
Q
Site 21
T237
P
R
P
L
T
Q
Q
T
L
T
S
Q
P
D
P
Site 22
T239
P
L
T
Q
Q
T
L
T
S
Q
P
D
P
S
S
Site 23
S240
L
T
Q
Q
T
L
T
S
Q
P
D
P
S
S
E
Site 24
S245
L
T
S
Q
P
D
P
S
S
E
E
R
P
P
A
Site 25
S246
T
S
Q
P
D
P
S
S
E
E
R
P
P
A
L
Site 26
Y275
G
Q
I
K
P
E
L
Y
Q
G
T
G
P
G
G
Site 27
S285
T
G
P
G
G
R
R
S
G
G
G
P
G
S
G
Site 28
S291
R
S
G
G
G
P
G
S
G
E
A
G
T
G
A
Site 29
T296
P
G
S
G
E
A
G
T
G
A
P
C
G
R
I
Site 30
Y309
R
I
S
F
A
L
R
Y
L
Y
G
S
D
Q
L
Site 31
S331
L
D
L
P
A
K
D
S
N
G
F
S
D
P
Y
Site 32
S335
A
K
D
S
N
G
F
S
D
P
Y
V
K
I
Y
Site 33
Y338
S
N
G
F
S
D
P
Y
V
K
I
Y
L
L
P
Site 34
Y342
S
D
P
Y
V
K
I
Y
L
L
P
D
R
K
K
Site 35
T359
Q
T
K
V
H
R
K
T
L
N
P
V
F
N
E
Site 36
S385
A
Q
R
K
L
H
F
S
V
Y
D
F
D
R
F
Site 37
Y387
R
K
L
H
F
S
V
Y
D
F
D
R
F
S
R
Site 38
S393
V
Y
D
F
D
R
F
S
R
H
D
L
I
G
Q
Site 39
T449
L
P
T
A
G
R
L
T
V
T
I
I
K
A
S
Site 40
T464
N
L
K
A
M
D
L
T
G
F
S
D
P
Y
V
Site 41
S467
A
M
D
L
T
G
F
S
D
P
Y
V
K
A
S
Site 42
S474
S
D
P
Y
V
K
A
S
L
I
S
E
G
R
R
Site 43
S477
Y
V
K
A
S
L
I
S
E
G
R
R
L
K
K
Site 44
T487
R
R
L
K
K
R
K
T
S
I
K
K
N
T
L
Site 45
S488
R
L
K
K
R
K
T
S
I
K
K
N
T
L
N
Site 46
T493
K
T
S
I
K
K
N
T
L
N
P
T
Y
N
E
Site 47
Y498
K
N
T
L
N
P
T
Y
N
E
A
L
V
F
D
Site 48
T572
H
Q
L
V
E
E
K
T
V
T
S
F
T
K
G
Site 49
T574
L
V
E
E
K
T
V
T
S
F
T
K
G
S
K
Site 50
S575
V
E
E
K
T
V
T
S
F
T
K
G
S
K
G
Site 51
S584
T
K
G
S
K
G
L
S
E
K
E
N
S
E
_
Site 52
S589
G
L
S
E
K
E
N
S
E
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation