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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LPIN3
Full Name:
Phosphatidate phosphatase LPIN3
Alias:
Lipin 3-like; LIPN3L
Type:
Nucleus protein
Mass (Da):
93614
Number AA:
851
UniProt ID:
Q9BQK8
International Prot ID:
IPI00556641
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y19
F
G
T
V
K
E
L
Y
R
G
L
N
P
A
T
Site 2
T26
Y
R
G
L
N
P
A
T
L
S
G
G
I
D
V
Site 3
S42
V
V
K
Q
V
D
G
S
F
R
C
S
P
F
H
Site 4
S46
V
D
G
S
F
R
C
S
P
F
H
V
R
F
G
Site 5
S60
G
K
L
G
V
L
R
S
R
E
K
V
V
D
I
Site 6
S94
F
F
V
Q
E
L
E
S
D
D
E
H
V
P
P
Site 7
S106
V
P
P
G
L
C
T
S
P
I
P
W
G
G
L
Site 8
S114
P
I
P
W
G
G
L
S
G
F
P
S
D
S
Q
Site 9
S118
G
G
L
S
G
F
P
S
D
S
Q
L
G
T
A
Site 10
S120
L
S
G
F
P
S
D
S
Q
L
G
T
A
S
E
Site 11
T124
P
S
D
S
Q
L
G
T
A
S
E
P
E
G
L
Site 12
S126
D
S
Q
L
G
T
A
S
E
P
E
G
L
V
M
Site 13
T136
E
G
L
V
M
A
G
T
A
S
T
G
R
R
K
Site 14
S138
L
V
M
A
G
T
A
S
T
G
R
R
K
R
R
Site 15
T139
V
M
A
G
T
A
S
T
G
R
R
K
R
R
R
Site 16
T159
Q
K
E
D
A
V
A
T
D
S
S
P
E
E
L
Site 17
S161
E
D
A
V
A
T
D
S
S
P
E
E
L
E
A
Site 18
S162
D
A
V
A
T
D
S
S
P
E
E
L
E
A
G
Site 19
S175
A
G
A
E
S
E
L
S
L
P
E
K
L
R
P
Site 20
S194
V
Q
L
E
E
K
S
S
L
Q
P
K
D
I
Y
Site 21
Y201
S
L
Q
P
K
D
I
Y
P
Y
S
D
G
E
W
Site 22
Y203
Q
P
K
D
I
Y
P
Y
S
D
G
E
W
P
P
Site 23
S204
P
K
D
I
Y
P
Y
S
D
G
E
W
P
P
Q
Site 24
S213
G
E
W
P
P
Q
A
S
L
S
A
G
E
L
T
Site 25
S215
W
P
P
Q
A
S
L
S
A
G
E
L
T
S
P
Site 26
T220
S
L
S
A
G
E
L
T
S
P
K
S
D
S
E
Site 27
S221
L
S
A
G
E
L
T
S
P
K
S
D
S
E
L
Site 28
S224
G
E
L
T
S
P
K
S
D
S
E
L
E
V
R
Site 29
S226
L
T
S
P
K
S
D
S
E
L
E
V
R
T
P
Site 30
T232
D
S
E
L
E
V
R
T
P
E
P
S
P
L
R
Site 31
S236
E
V
R
T
P
E
P
S
P
L
R
A
E
S
H
Site 32
S262
A
R
A
E
R
P
E
S
S
V
V
L
E
G
R
Site 33
S263
R
A
E
R
P
E
S
S
V
V
L
E
G
R
A
Site 34
S274
E
G
R
A
G
A
T
S
P
P
R
G
G
P
S
Site 35
S281
S
P
P
R
G
G
P
S
T
P
S
T
S
V
A
Site 36
T282
P
P
R
G
G
P
S
T
P
S
T
S
V
A
G
Site 37
S284
R
G
G
P
S
T
P
S
T
S
V
A
G
G
V
Site 38
T285
G
G
P
S
T
P
S
T
S
V
A
G
G
V
D
Site 39
S286
G
P
S
T
P
S
T
S
V
A
G
G
V
D
P
Site 40
T311
G
A
D
L
Q
P
D
T
E
D
P
T
L
V
G
Site 41
T315
Q
P
D
T
E
D
P
T
L
V
G
P
P
L
H
Site 42
T323
L
V
G
P
P
L
H
T
P
E
T
E
E
S
K
Site 43
T326
P
P
L
H
T
P
E
T
E
E
S
K
T
Q
S
Site 44
S329
H
T
P
E
T
E
E
S
K
T
Q
S
S
G
D
Site 45
T331
P
E
T
E
E
S
K
T
Q
S
S
G
D
M
G
Site 46
S333
T
E
E
S
K
T
Q
S
S
G
D
M
G
L
P
Site 47
S343
D
M
G
L
P
P
A
S
K
S
W
S
W
A
T
Site 48
S345
G
L
P
P
A
S
K
S
W
S
W
A
T
L
E
Site 49
S347
P
P
A
S
K
S
W
S
W
A
T
L
E
V
P
Site 50
S364
T
G
Q
P
E
R
V
S
R
G
K
G
S
P
K
Site 51
S369
R
V
S
R
G
K
G
S
P
K
R
S
Q
H
L
Site 52
S373
G
K
G
S
P
K
R
S
Q
H
L
G
P
S
D
Site 53
Y382
H
L
G
P
S
D
I
Y
L
D
D
L
P
S
L
Site 54
S388
I
Y
L
D
D
L
P
S
L
D
S
E
N
A
A
Site 55
S391
D
D
L
P
S
L
D
S
E
N
A
A
L
Y
F
Site 56
Y397
D
S
E
N
A
A
L
Y
F
P
Q
S
D
S
G
Site 57
S401
A
A
L
Y
F
P
Q
S
D
S
G
L
G
A
R
Site 58
S411
G
L
G
A
R
R
W
S
E
P
S
S
Q
K
S
Site 59
S414
A
R
R
W
S
E
P
S
S
Q
K
S
L
R
D
Site 60
S415
R
R
W
S
E
P
S
S
Q
K
S
L
R
D
P
Site 61
S418
S
E
P
S
S
Q
K
S
L
R
D
P
N
P
E
Site 62
T431
P
E
H
E
P
E
P
T
L
D
T
V
D
T
I
Site 63
T434
E
P
E
P
T
L
D
T
V
D
T
I
A
L
S
Site 64
S449
L
C
G
G
L
A
D
S
R
D
I
S
L
E
K
Site 65
S453
L
A
D
S
R
D
I
S
L
E
K
F
N
Q
H
Site 66
S461
L
E
K
F
N
Q
H
S
V
S
Y
Q
D
L
T
Site 67
S463
K
F
N
Q
H
S
V
S
Y
Q
D
L
T
K
N
Site 68
T468
S
V
S
Y
Q
D
L
T
K
N
P
G
L
L
D
Site 69
S510
F
Q
K
N
L
P
K
S
T
M
D
K
L
E
R
Site 70
S542
D
F
L
A
E
E
R
S
A
Q
K
E
K
T
A
Site 71
T548
R
S
A
Q
K
E
K
T
A
A
K
E
Q
Q
G
Site 72
T558
K
E
Q
Q
G
E
K
T
E
V
L
S
S
D
D
Site 73
S563
E
K
T
E
V
L
S
S
D
D
D
A
P
D
S
Site 74
S570
S
D
D
D
A
P
D
S
P
V
I
L
E
I
P
Site 75
S582
E
I
P
S
L
P
P
S
T
P
P
S
T
P
T
Site 76
T583
I
P
S
L
P
P
S
T
P
P
S
T
P
T
Y
Site 77
S586
L
P
P
S
T
P
P
S
T
P
T
Y
K
K
S
Site 78
T587
P
P
S
T
P
P
S
T
P
T
Y
K
K
S
L
Site 79
T589
S
T
P
P
S
T
P
T
Y
K
K
S
L
R
L
Site 80
Y590
T
P
P
S
T
P
T
Y
K
K
S
L
R
L
S
Site 81
S593
S
T
P
T
Y
K
K
S
L
R
L
S
S
D
Q
Site 82
S597
Y
K
K
S
L
R
L
S
S
D
Q
I
R
R
L
Site 83
S598
K
K
S
L
R
L
S
S
D
Q
I
R
R
L
N
Site 84
S616
G
A
N
D
V
V
F
S
V
T
T
Q
Y
Q
G
Site 85
T650
S
D
I
D
G
T
I
T
K
S
D
A
L
G
H
Site 86
S652
I
D
G
T
I
T
K
S
D
A
L
G
H
I
L
Site 87
T667
P
Q
L
G
K
D
W
T
H
Q
G
I
T
S
L
Site 88
Y675
H
Q
G
I
T
S
L
Y
H
K
I
Q
L
N
G
Site 89
S707
K
G
Y
L
Q
W
V
S
E
G
G
C
S
L
P
Site 90
Y761
L
P
H
G
Q
P
F
Y
A
A
F
G
N
R
P
Site 91
Y774
R
P
N
D
V
F
A
Y
R
Q
V
G
L
P
E
Site 92
S782
R
Q
V
G
L
P
E
S
R
I
F
T
V
N
P
Site 93
T786
L
P
E
S
R
I
F
T
V
N
P
R
G
E
L
Site 94
S803
E
L
I
K
N
H
K
S
T
Y
E
R
L
G
E
Site 95
Y805
I
K
N
H
K
S
T
Y
E
R
L
G
E
V
V
Site 96
S824
P
P
V
A
R
G
P
S
T
D
L
A
N
P
E
Site 97
T825
P
V
A
R
G
P
S
T
D
L
A
N
P
E
Y
Site 98
Y832
T
D
L
A
N
P
E
Y
S
N
F
C
Y
W
R
Site 99
Y837
P
E
Y
S
N
F
C
Y
W
R
E
P
L
P
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation