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Updated November 2019
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Protein Info
Short Name:
FAM83C
Full Name:
Protein FAM83C
Alias:
Type:
Mass (Da):
81078
Number AA:
747
UniProt ID:
Q9BQN1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
K
L
P
W
W
R
E
S
S
P
L
V
L
R
H
Site 2
S35
L
P
W
W
R
E
S
S
P
L
V
L
R
H
S
Site 3
Y60
L
E
R
G
E
A
A
Y
L
R
V
I
S
E
E
Site 4
S65
A
A
Y
L
R
V
I
S
E
E
R
E
L
P
F
Site 5
S74
E
R
E
L
P
F
L
S
A
L
D
V
D
Y
M
Site 6
Y80
L
S
A
L
D
V
D
Y
M
T
S
H
V
R
G
Site 7
T82
A
L
D
V
D
Y
M
T
S
H
V
R
G
G
P
Site 8
S83
L
D
V
D
Y
M
T
S
H
V
R
G
G
P
E
Site 9
S92
V
R
G
G
P
E
L
S
E
A
Q
G
Q
E
A
Site 10
S100
E
A
Q
G
Q
E
A
S
G
P
D
R
L
S
L
Site 11
S106
A
S
G
P
D
R
L
S
L
L
S
E
V
T
S
Site 12
S109
P
D
R
L
S
L
L
S
E
V
T
S
G
T
Y
Site 13
T115
L
S
E
V
T
S
G
T
Y
F
P
M
A
S
D
Site 14
Y116
S
E
V
T
S
G
T
Y
F
P
M
A
S
D
I
Site 15
S121
G
T
Y
F
P
M
A
S
D
I
D
P
P
D
L
Site 16
T171
F
L
F
S
Q
A
H
T
V
V
A
V
V
M
D
Site 17
S193
L
C
D
L
M
E
A
S
S
R
R
G
V
P
V
Site 18
S194
C
D
L
M
E
A
S
S
R
R
G
V
P
V
Y
Site 19
Y201
S
R
R
G
V
P
V
Y
L
L
L
A
Q
E
H
Site 20
T234
P
N
M
R
V
R
S
T
C
G
D
T
Y
C
S
Site 21
T238
V
R
S
T
C
G
D
T
Y
C
S
K
A
G
R
Site 22
Y239
R
S
T
C
G
D
T
Y
C
S
K
A
G
R
R
Site 23
T248
S
K
A
G
R
R
F
T
G
Q
A
L
E
K
F
Site 24
Y301
D
R
E
F
R
C
L
Y
A
E
S
Q
P
V
E
Site 25
S318
C
G
G
E
D
P
L
S
P
R
A
L
R
P
P
Site 26
S337
A
F
R
P
D
V
P
S
P
T
S
S
L
P
S
Site 27
T339
R
P
D
V
P
S
P
T
S
S
L
P
S
S
T
Site 28
S340
P
D
V
P
S
P
T
S
S
L
P
S
S
T
S
Site 29
S341
D
V
P
S
P
T
S
S
L
P
S
S
T
S
L
Site 30
S344
S
P
T
S
S
L
P
S
S
T
S
L
S
S
I
Site 31
S345
P
T
S
S
L
P
S
S
T
S
L
S
S
I
K
Site 32
S347
S
S
L
P
S
S
T
S
L
S
S
I
K
Q
S
Site 33
S349
L
P
S
S
T
S
L
S
S
I
K
Q
S
P
L
Site 34
S350
P
S
S
T
S
L
S
S
I
K
Q
S
P
L
M
Site 35
S354
S
L
S
S
I
K
Q
S
P
L
M
G
R
S
S
Site 36
S360
Q
S
P
L
M
G
R
S
S
Y
L
A
L
P
G
Site 37
S361
S
P
L
M
G
R
S
S
Y
L
A
L
P
G
G
Site 38
S372
L
P
G
G
G
D
C
S
D
T
G
V
V
S
S
Site 39
T374
G
G
G
D
C
S
D
T
G
V
V
S
S
S
L
Site 40
S378
C
S
D
T
G
V
V
S
S
S
L
G
P
A
R
Site 41
S380
D
T
G
V
V
S
S
S
L
G
P
A
R
R
E
Site 42
S389
G
P
A
R
R
E
A
S
G
Q
P
S
L
H
R
Site 43
S393
R
E
A
S
G
Q
P
S
L
H
R
Q
L
S
D
Site 44
S399
P
S
L
H
R
Q
L
S
D
P
N
H
G
S
P
Site 45
S405
L
S
D
P
N
H
G
S
P
P
G
L
Y
R
A
Site 46
Y410
H
G
S
P
P
G
L
Y
R
A
N
L
G
K
L
Site 47
Y420
N
L
G
K
L
G
A
Y
P
W
S
Q
S
S
P
Site 48
S423
K
L
G
A
Y
P
W
S
Q
S
S
P
A
L
N
Site 49
S425
G
A
Y
P
W
S
Q
S
S
P
A
L
N
H
N
Site 50
S426
A
Y
P
W
S
Q
S
S
P
A
L
N
H
N
S
Site 51
S433
S
P
A
L
N
H
N
S
T
S
P
L
T
L
A
Site 52
S449
G
S
P
L
L
P
R
S
R
P
L
L
Q
F
H
Site 53
S463
H
R
G
A
P
A
L
S
R
F
P
E
N
G
L
Site 54
S473
P
E
N
G
L
P
G
S
Q
E
P
S
P
L
R
Site 55
S477
L
P
G
S
Q
E
P
S
P
L
R
G
R
W
V
Site 56
T487
R
G
R
W
V
P
G
T
T
L
E
T
V
E
E
Site 57
T491
V
P
G
T
T
L
E
T
V
E
E
K
E
K
K
Site 58
S500
E
E
K
E
K
K
A
S
P
S
Q
S
R
G
Q
Site 59
S502
K
E
K
K
A
S
P
S
Q
S
R
G
Q
L
D
Site 60
S504
K
K
A
S
P
S
Q
S
R
G
Q
L
D
L
L
Site 61
S525
R
E
V
G
D
P
D
S
G
V
T
P
N
S
G
Site 62
T528
G
D
P
D
S
G
V
T
P
N
S
G
P
L
R
Site 63
S531
D
S
G
V
T
P
N
S
G
P
L
R
P
G
E
Site 64
S547
A
P
E
D
R
R
L
S
P
S
Q
A
D
S
Q
Site 65
S549
E
D
R
R
L
S
P
S
Q
A
D
S
Q
L
D
Site 66
S553
L
S
P
S
Q
A
D
S
Q
L
D
L
L
S
R
Site 67
S559
D
S
Q
L
D
L
L
S
R
A
L
G
T
G
G
Site 68
S572
G
G
A
P
E
L
G
S
L
R
P
G
D
R
A
Site 69
S586
A
L
E
D
R
R
L
S
L
N
Q
S
R
G
Q
Site 70
S590
R
R
L
S
L
N
Q
S
R
G
Q
S
D
L
L
Site 71
S594
L
N
Q
S
R
G
Q
S
D
L
L
M
Q
Y
P
Site 72
Y600
Q
S
D
L
L
M
Q
Y
P
K
A
Q
G
S
R
Site 73
T612
G
S
R
V
P
L
E
T
N
S
S
A
R
P
A
Site 74
S615
V
P
L
E
T
N
S
S
A
R
P
A
R
R
A
Site 75
T629
A
P
D
E
R
R
Q
T
L
G
H
S
Q
L
D
Site 76
S633
R
R
Q
T
L
G
H
S
Q
L
D
L
I
T
K
Site 77
S657
G
P
N
G
L
P
I
S
S
P
A
R
T
A
G
Site 78
S658
P
N
G
L
P
I
S
S
P
A
R
T
A
G
A
Site 79
T662
P
I
S
S
P
A
R
T
A
G
A
G
S
G
D
Site 80
T674
S
G
D
E
K
R
L
T
L
G
H
S
K
L
D
Site 81
S678
K
R
L
T
L
G
H
S
K
L
D
L
I
T
K
Site 82
T684
H
S
K
L
D
L
I
T
K
Y
H
Q
L
H
G
Site 83
Y686
K
L
D
L
I
T
K
Y
H
Q
L
H
G
A
R
Site 84
T696
L
H
G
A
R
Q
G
T
E
P
G
G
P
K
G
Site 85
S711
G
H
L
N
G
G
N
S
D
L
V
R
D
E
K
Site 86
T721
V
R
D
E
K
R
L
T
L
G
H
S
K
L
D
Site 87
Y733
K
L
D
L
I
T
K
Y
N
K
S
K
F
K
Q
Site 88
S736
L
I
T
K
Y
N
K
S
K
F
K
Q
L
R
S
Site 89
S743
S
K
F
K
Q
L
R
S
R
F
E
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation