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Updated November 2019
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Protein Info
Short Name:
MESP1
Full Name:
Mesoderm posterior protein 1
Alias:
Class C basic helix-loop-helix protein 5
Type:
Mass (Da):
28501
Number AA:
268
UniProt ID:
Q9BRJ9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
Q
P
L
C
P
P
L
S
E
S
W
M
L
S
A
Site 2
S16
L
S
E
S
W
M
L
S
A
A
W
G
P
T
R
Site 3
T22
L
S
A
A
W
G
P
T
R
R
P
P
P
S
D
Site 4
S28
P
T
R
R
P
P
P
S
D
K
D
C
G
R
S
Site 5
S35
S
D
K
D
C
G
R
S
L
V
S
S
P
D
S
Site 6
S38
D
C
G
R
S
L
V
S
S
P
D
S
W
G
S
Site 7
S39
C
G
R
S
L
V
S
S
P
D
S
W
G
S
T
Site 8
S42
S
L
V
S
S
P
D
S
W
G
S
T
P
A
D
Site 9
S45
S
S
P
D
S
W
G
S
T
P
A
D
S
P
V
Site 10
T46
S
P
D
S
W
G
S
T
P
A
D
S
P
V
A
Site 11
S50
W
G
S
T
P
A
D
S
P
V
A
S
P
A
R
Site 12
S54
P
A
D
S
P
V
A
S
P
A
R
P
G
T
L
Site 13
T60
A
S
P
A
R
P
G
T
L
R
D
P
R
A
P
Site 14
S68
L
R
D
P
R
A
P
S
V
G
R
R
G
A
R
Site 15
S76
V
G
R
R
G
A
R
S
S
R
L
G
S
G
Q
Site 16
S77
G
R
R
G
A
R
S
S
R
L
G
S
G
Q
R
Site 17
S81
A
R
S
S
R
L
G
S
G
Q
R
Q
S
A
S
Site 18
S86
L
G
S
G
Q
R
Q
S
A
S
E
R
E
K
L
Site 19
S88
S
G
Q
R
Q
S
A
S
E
R
E
K
L
R
M
Site 20
T97
R
E
K
L
R
M
R
T
L
A
R
A
L
H
E
Site 21
S112
L
R
R
F
L
P
P
S
V
A
P
A
G
Q
S
Site 22
T125
Q
S
L
T
K
I
E
T
L
R
L
A
I
R
Y
Site 23
S143
L
S
A
V
L
G
L
S
E
E
S
L
Q
R
R
Site 24
S146
V
L
G
L
S
E
E
S
L
Q
R
R
C
R
Q
Site 25
S159
R
Q
R
G
D
A
G
S
P
R
G
C
P
L
C
Site 26
S200
S
A
V
R
A
G
A
S
W
G
S
P
P
A
C
Site 27
S203
R
A
G
A
S
W
G
S
P
P
A
C
P
G
A
Site 28
S237
E
G
Q
A
M
E
P
S
P
P
S
P
L
L
P
Site 29
S240
A
M
E
P
S
P
P
S
P
L
L
P
G
D
V
Site 30
S258
L
E
T
W
M
P
L
S
P
L
E
W
L
P
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation