PhosphoNET

           
Protein Info 
   
Short Name:  SFRS2B
Full Name:  Serine/arginine-rich splicing factor 8
Alias:  Pre-mRNA-splicing factor SRP46; SFR2B; SRP46; SRp46 splicing factor
Type:  RNA binding protein
Mass (Da):  32288
Number AA:  282
UniProt ID:  Q9BRL6
International Prot ID:  not found
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634  GO:0043226  GO:0043227 Uniprot OncoNet
Molecular Function:  GO:0003723  GO:0000166  GO:0003723 PhosphoSite+ KinaseNET
Biological Process:  GO:0008380  GO:0006397  GO:0006397 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S2______MSCGRPPPD
Site 2T22TLKVDNLTYRTSPDS
Site 3Y23LKVDNLTYRTSPDSL
Site 4T25VDNLTYRTSPDSLRR
Site 5S26DNLTYRTSPDSLRRV
Site 6S29TYRTSPDSLRRVFEK
Site 7Y37LRRVFEKYGRVGDVY
Site 8Y44YGRVGDVYIPREPHT
Site 9T51YIPREPHTKAPRGFA
Site 10Y92LRVQVARYGRRDLPR
Site 11S100GRRDLPRSRQGEPRG
Site 12S109QGEPRGRSRGGGYGR
Site 13Y114GRSRGGGYGRRSRSY
Site 14S118GGGYGRRSRSYGRRS
Site 15S120GYGRRSRSYGRRSRS
Site 16Y121YGRRSRSYGRRSRSP
Site 17S125SRSYGRRSRSPRRRH
Site 18S127SYGRRSRSPRRRHRS
Site 19S134SPRRRHRSRSRGPSC
Site 20S136RRRHRSRSRGPSCSR
Site 21S140RSRSRGPSCSRSRSR
Site 22S142RSRGPSCSRSRSRSR
Site 23S144RGPSCSRSRSRSRYR
Site 24S146PSCSRSRSRSRYRGS
Site 25S148CSRSRSRSRYRGSRY
Site 26Y150RSRSRSRYRGSRYSR
Site 27S153SRSRYRGSRYSRSPY
Site 28Y155SRYRGSRYSRSPYSR
Site 29S156RYRGSRYSRSPYSRS
Site 30S158RGSRYSRSPYSRSPY
Site 31Y160SRYSRSPYSRSPYSR
Site 32S161RYSRSPYSRSPYSRS
Site 33S163SRSPYSRSPYSRSRY
Site 34Y165SPYSRSPYSRSRYSR
Site 35S166PYSRSPYSRSRYSRS
Site 36S168SRSPYSRSRYSRSPY
Site 37Y170SPYSRSRYSRSPYSR
Site 38S171PYSRSRYSRSPYSRS
Site 39S173SRSRYSRSPYSRSRY
Site 40Y175SRYSRSPYSRSRYRE
Site 41S176RYSRSPYSRSRYRES
Site 42S178SRSPYSRSRYRESRY
Site 43Y180SPYSRSRYRESRYGG
Site 44S183SRSRYRESRYGGSHY
Site 45Y185SRYRESRYGGSHYSS
Site 46S188RESRYGGSHYSSSGY
Site 47Y190SRYGGSHYSSSGYSN
Site 48S191RYGGSHYSSSGYSNS
Site 49S192YGGSHYSSSGYSNSR
Site 50S193GGSHYSSSGYSNSRY
Site 51Y195SHYSSSGYSNSRYSR
Site 52S196HYSSSGYSNSRYSRY
Site 53S198SSSGYSNSRYSRYHS
Site 54Y200SGYSNSRYSRYHSSR
Site 55S201GYSNSRYSRYHSSRS
Site 56Y203SNSRYSRYHSSRSHS
Site 57S205SRYSRYHSSRSHSKS
Site 58S206RYSRYHSSRSHSKSG
Site 59S208SRYHSSRSHSKSGSS
Site 60S210YHSSRSHSKSGSSTS
Site 61S212SSRSHSKSGSSTSSR
Site 62S214RSHSKSGSSTSSRSA
Site 63S215SHSKSGSSTSSRSAS
Site 64T216HSKSGSSTSSRSAST
Site 65S217SKSGSSTSSRSASTS
Site 66S218KSGSSTSSRSASTSK
Site 67S220GSSTSSRSASTSKSS
Site 68S222STSSRSASTSKSSSA
Site 69T223TSSRSASTSKSSSAR
Site 70S224SSRSASTSKSSSARR
Site 71S226RSASTSKSSSARRSK
Site 72S227SASTSKSSSARRSKS
Site 73S228ASTSKSSSARRSKSS
Site 74S232KSSSARRSKSSSVSR
Site 75S234SSARRSKSSSVSRSR
Site 76S235SARRSKSSSVSRSRS
Site 77S236ARRSKSSSVSRSRSR
Site 78S238RSKSSSVSRSRSRSR
Site 79S240KSSSVSRSRSRSRSS
Site 80S242SSVSRSRSRSRSSSM
Site 81S244VSRSRSRSRSSSMTR
Site 82S246RSRSRSRSSSMTRSP
Site 83S247SRSRSRSSSMTRSPP
Site 84S248RSRSRSSSMTRSPPR
Site 85T250RSRSSSMTRSPPRVS
Site 86S252RSSSMTRSPPRVSKR
Site 87S257TRSPPRVSKRKSKSR
Site 88S261PRVSKRKSKSRSRSK
Site 89S263VSKRKSKSRSRSKRP
Site 90S265KRKSKSRSRSKRPPK
Site 91S267KSKSRSRSKRPPKSP
Site 92S273RSKRPPKSPEEEGQM
Site 93S281PEEEGQMSS______
Site 94S282EEEGQMSS_______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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