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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PAAF1
Full Name:
Proteasomal ATPase-associated factor 1
Alias:
Protein G-16;WD repeat-containing protein 71
Type:
Mass (Da):
42190
Number AA:
392
UniProt ID:
Q9BRP4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
A
P
L
R
I
Q
S
D
W
A
Q
A
L
R
Site 2
S25
D
E
G
E
A
W
L
S
C
H
P
P
G
K
P
Site 3
S33
C
H
P
P
G
K
P
S
L
Y
G
S
L
T
C
Site 4
Y35
P
P
G
K
P
S
L
Y
G
S
L
T
C
Q
G
Site 5
S37
G
K
P
S
L
Y
G
S
L
T
C
Q
G
I
G
Site 6
S54
G
I
P
E
V
T
A
S
E
G
F
T
V
N
E
Site 7
T58
V
T
A
S
E
G
F
T
V
N
E
I
N
K
K
Site 8
S70
N
K
K
S
I
H
I
S
C
P
K
E
N
A
S
Site 9
S77
S
C
P
K
E
N
A
S
S
K
F
L
A
P
Y
Site 10
S78
C
P
K
E
N
A
S
S
K
F
L
A
P
Y
T
Site 11
Y84
S
S
K
F
L
A
P
Y
T
T
F
S
R
I
H
Site 12
T85
S
K
F
L
A
P
Y
T
T
F
S
R
I
H
T
Site 13
T86
K
F
L
A
P
Y
T
T
F
S
R
I
H
T
K
Site 14
S88
L
A
P
Y
T
T
F
S
R
I
H
T
K
S
I
Site 15
T92
T
T
F
S
R
I
H
T
K
S
I
T
C
L
D
Site 16
T96
R
I
H
T
K
S
I
T
C
L
D
I
S
S
R
Site 17
S109
S
R
G
G
L
G
V
S
S
S
T
D
G
T
M
Site 18
S110
R
G
G
L
G
V
S
S
S
T
D
G
T
M
K
Site 19
S111
G
G
L
G
V
S
S
S
T
D
G
T
M
K
I
Site 20
T115
V
S
S
S
T
D
G
T
M
K
I
W
Q
A
S
Site 21
T171
E
D
A
S
C
V
V
T
F
K
G
H
K
G
G
Site 22
T182
H
K
G
G
I
L
D
T
A
I
V
D
R
G
R
Site 23
S193
D
R
G
R
N
V
V
S
A
S
R
D
G
T
A
Site 24
S195
G
R
N
V
V
S
A
S
R
D
G
T
A
R
L
Site 25
T199
V
S
A
S
R
D
G
T
A
R
L
W
D
C
G
Site 26
S232
A
V
G
A
A
D
N
S
I
N
L
G
S
P
E
Site 27
S237
D
N
S
I
N
L
G
S
P
E
Q
M
P
S
E
Site 28
S243
G
S
P
E
Q
M
P
S
E
R
E
V
G
T
E
Site 29
Y304
G
T
Q
D
G
N
I
Y
Q
L
D
V
R
S
P
Site 30
S310
I
Y
Q
L
D
V
R
S
P
R
A
P
V
Q
V
Site 31
S338
V
R
D
G
F
I
A
S
Q
G
D
G
S
C
F
Site 32
Y366
G
A
D
C
D
P
V
Y
K
V
A
T
W
E
K
Site 33
Y376
A
T
W
E
K
Q
I
Y
T
C
C
R
D
G
L
Site 34
Y387
R
D
G
L
V
R
R
Y
Q
L
S
D
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation