PhosphoNET

           
Protein Info 
   
Short Name:  PYGO2
Full Name:  Pygopus homolog 2
Alias:  FLJ33226; Pygopus homologue 2 (Drosophila) (Pygopus homologue 2 (Drosophila), isoform CRA_b); Pygopus homologue2
Type:  Signalling protein. Compoent of nuclear beta-catenin/TCF complex.
Mass (Da):  41244
Number AA:  406
UniProt ID:  Q9BRQ0
International Prot ID:  IPI00042099
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634  GO:0043226  GO:0043227 Uniprot OncoNet
Molecular Function:  GO:0005488  GO:0005515  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0007154  GO:0007165  GO:0007166 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S26APPPAPPSTGRKQGK
Site 2T27PPPAPPSTGRKQGKA
Site 3S40KAGLQMKSPEKKRRK
Site 4S48PEKKRRKSNTQGPAY
Site 5T50KKRRKSNTQGPAYSH
Site 6Y55SNTQGPAYSHLTEFA
Site 7S97AAPPFLGSPVPFGGF
Site 8Y118AGQVPPGYSTGGGGG
Site 9S119GQVPPGYSTGGGGGP
Site 10Y154MPPQGPGYPPPGNMN
Site 11S164PGNMNFPSQPFNQPL
Site 12S176QPLGQNFSPPSGQMM
Site 13S179GQNFSPPSGQMMPGP
Site 14S195GGFGPMISPTMGQPP
Site 15T197FGPMISPTMGQPPRA
Site 16S210RAELGPPSLSQRFAQ
Site 17S212ELGPPSLSQRFAQPG
Site 18S225PGAPFGPSPLQRPGQ
Site 19S236RPGQGLPSLPPNTSP
Site 20S242PSLPPNTSPFPGPDP
Site 21S268KPLNPPASTAFPQEP
Site 22S277AFPQEPHSGSPAAAV
Site 23S279PQEPHSGSPAAAVNG
Site 24S290AVNGNQPSFPPNSSG
Site 25S295QPSFPPNSSGRGGGT
Site 26S296PSFPPNSSGRGGGTP
Site 27T302SSGRGGGTPDANSLA
Site 28S307GGTPDANSLAPPGKA
Site 29S318PGKAGGGSGPQPPPG
Site 30Y328QPPPGLVYPCGACRS
Site 31S364ECTGMTESAYGLLTT
Site 32Y366TGMTESAYGLLTTEA
Site 33S390LKTKEIQSVYIREGM
Site 34Y392TKEIQSVYIREGMGQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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