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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMEM142C
Full Name:
Protein orai-3
Alias:
MGC13024; ORAI calcium release-activated calcium modulator 3; ORAI3
Type:
Mass (Da):
31500
Number AA:
UniProt ID:
Q9BRQ5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
P
L
N
P
E
G
E
S
P
A
G
S
A
T
Y
Site 2
S24
E
G
E
S
P
A
G
S
A
T
Y
R
E
F
V
Site 3
T26
E
S
P
A
G
S
A
T
Y
R
E
F
V
H
R
Site 4
Y35
R
E
F
V
H
R
G
Y
L
D
L
M
G
A
S
Site 5
S45
L
M
G
A
S
Q
H
S
L
R
A
L
S
W
R
Site 6
S50
Q
H
S
L
R
A
L
S
W
R
R
L
Y
L
S
Site 7
Y55
A
L
S
W
R
R
L
Y
L
S
R
A
K
L
K
Site 8
S57
S
W
R
R
L
Y
L
S
R
A
K
L
K
A
S
Site 9
S64
S
R
A
K
L
K
A
S
S
R
T
S
A
L
L
Site 10
S65
R
A
K
L
K
A
S
S
R
T
S
A
L
L
S
Site 11
S86
M
V
E
V
Q
L
E
S
D
H
E
Y
P
P
G
Site 12
Y90
Q
L
E
S
D
H
E
Y
P
P
G
L
L
V
A
Site 13
S134
S
N
I
H
N
L
N
S
V
H
Q
S
P
H
Q
Site 14
S138
N
L
N
S
V
H
Q
S
P
H
Q
R
L
H
R
Site 15
Y146
P
H
Q
R
L
H
R
Y
V
E
L
A
W
G
F
Site 16
T183
P
I
G
A
P
L
D
T
P
T
P
M
V
P
T
Site 17
T185
G
A
P
L
D
T
P
T
P
M
V
P
T
S
R
Site 18
S205
A
P
V
A
T
S
L
S
P
A
S
N
L
P
R
Site 19
S208
A
T
S
L
S
P
A
S
N
L
P
R
S
S
A
Site 20
S213
P
A
S
N
L
P
R
S
S
A
S
A
A
P
S
Site 21
S214
A
S
N
L
P
R
S
S
A
S
A
A
P
S
Q
Site 22
S216
N
L
P
R
S
S
A
S
A
A
P
S
Q
A
E
Site 23
S220
S
S
A
S
A
A
P
S
Q
A
E
P
A
C
P
Site 24
S269
F
A
L
H
F
Y
R
S
L
V
A
H
K
T
D
Site 25
T275
R
S
L
V
A
H
K
T
D
R
Y
K
Q
E
L
Site 26
Y278
V
A
H
K
T
D
R
Y
K
Q
E
L
E
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation