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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TINF2
Full Name:
TERF1-interacting nuclear factor 2
Alias:
TERF1 (TRF1)-interacting nuclear factor 2; TIN2; TRF1-interacting nuclear protein 2
Type:
DNA repair protein. Shelterin complex protein.
Mass (Da):
50023
Number AA:
451
UniProt ID:
Q9BSI4
International Prot ID:
IPI00074109
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000783
GO:0005654
GO:0010370
Uniprot
OncoNet
Molecular Function:
GO:0008022
GO:0042162
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0050680
GO:0010836
GO:0032211
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S90
L
N
H
H
F
P
E
S
G
P
I
V
R
D
P
Site 2
T113
K
I
L
E
A
Q
E
T
F
Y
Q
Q
V
K
Q
Site 3
Y115
L
E
A
Q
E
T
F
Y
Q
Q
V
K
Q
L
S
Site 4
S130
E
A
P
V
D
L
A
S
K
L
Q
E
L
E
Q
Site 5
Y139
L
Q
E
L
E
Q
E
Y
G
E
P
F
L
A
A
Site 6
T164
Q
L
E
K
A
L
P
T
P
Q
A
Q
Q
L
Q
Site 7
S175
Q
Q
L
Q
D
V
L
S
W
M
Q
P
G
V
S
Site 8
S186
P
G
V
S
I
T
S
S
L
A
W
R
Q
Y
G
Site 9
Y192
S
S
L
A
W
R
Q
Y
G
V
D
M
G
W
L
Site 10
S208
P
E
C
S
V
T
D
S
V
N
L
A
E
P
M
Site 11
T238
L
P
K
A
K
P
G
T
H
L
P
Q
G
P
S
Site 12
S245
T
H
L
P
Q
G
P
S
S
R
T
H
P
E
P
Site 13
S246
H
L
P
Q
G
P
S
S
R
T
H
P
E
P
L
Site 14
S270
L
G
R
R
R
V
Q
S
Q
W
A
S
T
R
G
Site 15
S274
R
V
Q
S
Q
W
A
S
T
R
G
G
H
K
E
Site 16
T284
G
G
H
K
E
R
P
T
V
M
L
F
P
F
R
Site 17
S295
F
P
F
R
N
L
G
S
P
T
Q
V
I
S
K
Site 18
T297
F
R
N
L
G
S
P
T
Q
V
I
S
K
P
E
Site 19
S301
G
S
P
T
Q
V
I
S
K
P
E
S
K
E
E
Site 20
S305
Q
V
I
S
K
P
E
S
K
E
E
H
A
I
Y
Site 21
Y312
S
K
E
E
H
A
I
Y
T
A
D
L
A
M
G
Site 22
S324
A
M
G
T
R
A
A
S
T
G
K
S
K
S
P
Site 23
S328
R
A
A
S
T
G
K
S
K
S
P
C
Q
T
L
Site 24
S330
A
S
T
G
K
S
K
S
P
C
Q
T
L
G
G
Site 25
T334
K
S
K
S
P
C
Q
T
L
G
G
R
A
L
K
Site 26
Y360
K
E
N
C
L
D
C
Y
M
D
P
L
R
L
S
Site 27
S367
Y
M
D
P
L
R
L
S
L
L
P
P
R
A
R
Site 28
S396
I
G
D
L
V
L
D
S
D
E
E
E
N
G
Q
Site 29
S409
G
Q
G
E
G
K
E
S
L
E
N
Y
Q
K
T
Site 30
Y413
G
K
E
S
L
E
N
Y
Q
K
T
K
F
D
T
Site 31
T420
Y
Q
K
T
K
F
D
T
L
I
P
T
L
C
E
Site 32
S440
G
H
G
A
I
P
V
S
S
C
D
C
R
D
S
Site 33
S441
H
G
A
I
P
V
S
S
C
D
C
R
D
S
S
Site 34
S447
S
S
C
D
C
R
D
S
S
R
P
L
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation