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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EFCAB4B
Full Name:
EF-hand calcium-binding domain-containing protein 4B
Alias:
EFC4B; EF-hand calcium binding domain 4B; EF-hand calcium-binding domain-containing 4B
Type:
Mass (Da):
45592
Number AA:
395
UniProt ID:
Q9BSW2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
A
P
D
G
R
V
V
S
R
P
Q
R
L
G
Q
Site 2
S19
P
Q
R
L
G
Q
G
S
G
Q
G
P
K
G
S
Site 3
S26
S
G
Q
G
P
K
G
S
G
A
C
L
H
P
L
Site 4
S35
A
C
L
H
P
L
D
S
L
E
Q
K
E
T
Q
Site 5
T41
D
S
L
E
Q
K
E
T
Q
E
Q
T
S
G
Q
Site 6
T61
K
A
Q
E
F
F
Q
T
C
D
A
E
G
K
G
Site 7
S85
L
H
K
E
L
P
L
S
L
E
E
L
E
D
V
Site 8
Y103
L
D
A
D
G
N
G
Y
L
T
P
Q
E
F
T
Site 9
T105
A
D
G
N
G
Y
L
T
P
Q
E
F
T
T
G
Site 10
S119
G
F
S
H
F
F
F
S
Q
N
N
P
S
Q
E
Site 11
S124
F
F
S
Q
N
N
P
S
Q
E
D
A
G
E
Q
Site 12
Y141
Q
R
H
E
E
K
V
Y
L
S
R
G
D
E
D
Site 13
S177
Q
K
V
L
E
D
E
S
D
V
K
Q
L
W
L
Site 14
S195
K
E
E
P
H
L
L
S
N
F
E
D
F
L
T
Site 15
T202
S
N
F
E
D
F
L
T
R
I
I
S
Q
L
Q
Site 16
S206
D
F
L
T
R
I
I
S
Q
L
Q
E
A
H
E
Site 17
Y229
L
K
R
K
I
A
A
Y
D
E
E
I
Q
H
L
Site 18
Y237
D
E
E
I
Q
H
L
Y
E
E
M
E
Q
Q
I
Site 19
S246
E
M
E
Q
Q
I
K
S
E
K
E
Q
F
L
L
Site 20
T256
E
Q
F
L
L
K
D
T
E
R
F
Q
A
R
S
Site 21
S263
T
E
R
F
Q
A
R
S
Q
E
L
E
Q
K
L
Site 22
T292
K
R
L
E
G
Q
C
T
A
L
H
H
D
K
H
Site 23
T301
L
H
H
D
K
H
E
T
K
A
E
N
T
K
L
Site 24
T311
E
N
T
K
L
K
L
T
N
Q
E
L
A
R
E
Site 25
T322
L
A
R
E
L
E
R
T
S
W
E
L
Q
D
A
Site 26
S323
A
R
E
L
E
R
T
S
W
E
L
Q
D
A
Q
Site 27
Y352
Q
E
K
E
M
E
V
Y
R
V
T
E
S
L
Q
Site 28
T355
E
M
E
V
Y
R
V
T
E
S
L
Q
R
E
K
Site 29
S357
E
V
Y
R
V
T
E
S
L
Q
R
E
K
A
G
Site 30
S388
V
L
R
A
P
P
R
S
L
G
S
E
G
P
V
Site 31
S391
A
P
P
R
S
L
G
S
E
G
P
V
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation