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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
INPP5K
Full Name:
Inositol polyphosphate 5-phosphatase K
Alias:
Skeletal muscle and kidney-enriched inositol phosphatase
Type:
Mass (Da):
51090
Number AA:
448
UniProt ID:
Q9BT40
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
S
S
R
K
L
S
G
P
K
G
R
R
L
Site 2
S15
G
P
K
G
R
R
L
S
I
H
V
V
T
W
N
Site 3
S33
A
A
P
P
L
D
L
S
D
L
L
Q
L
N
N
Site 4
S71
S
D
A
A
F
N
D
S
W
S
S
F
L
M
D
Site 5
Y109
A
K
Y
Q
H
L
P
Y
I
Q
I
L
S
T
K
Site 6
S114
L
P
Y
I
Q
I
L
S
T
K
S
T
P
T
G
Site 7
T118
Q
I
L
S
T
K
S
T
P
T
G
L
F
G
Y
Site 8
Y125
T
P
T
G
L
F
G
Y
W
G
N
K
G
G
V
Site 9
Y158
P
P
H
I
S
N
N
Y
Q
R
L
E
H
F
D
Site 10
Y214
E
S
I
K
N
R
C
Y
G
G
L
W
E
K
D
Site 11
S224
L
W
E
K
D
Q
L
S
I
A
K
K
H
D
P
Site 12
T246
G
R
L
L
F
P
P
T
Y
K
F
D
R
N
S
Site 13
Y247
R
L
L
F
P
P
T
Y
K
F
D
R
N
S
N
Site 14
S253
T
Y
K
F
D
R
N
S
N
D
Y
D
T
S
E
Site 15
Y256
F
D
R
N
S
N
D
Y
D
T
S
E
K
K
R
Site 16
T258
R
N
S
N
D
Y
D
T
S
E
K
K
R
K
P
Site 17
T268
K
K
R
K
P
A
W
T
D
R
I
L
W
R
L
Site 18
T285
Q
P
C
A
G
P
D
T
P
I
P
P
A
S
H
Site 19
S291
D
T
P
I
P
P
A
S
H
F
S
L
S
L
R
Site 20
S294
I
P
P
A
S
H
F
S
L
S
L
R
G
Y
S
Site 21
S296
P
A
S
H
F
S
L
S
L
R
G
Y
S
S
H
Site 22
Y300
F
S
L
S
L
R
G
Y
S
S
H
M
T
Y
G
Site 23
S301
S
L
S
L
R
G
Y
S
S
H
M
T
Y
G
I
Site 24
S302
L
S
L
R
G
Y
S
S
H
M
T
Y
G
I
S
Site 25
T305
R
G
Y
S
S
H
M
T
Y
G
I
S
D
H
K
Site 26
Y306
G
Y
S
S
H
M
T
Y
G
I
S
D
H
K
P
Site 27
S315
I
S
D
H
K
P
V
S
G
T
F
D
L
E
L
Site 28
S348
V
E
N
D
M
M
V
S
Y
S
S
T
S
D
F
Site 29
Y349
E
N
D
M
M
V
S
Y
S
S
T
S
D
F
P
Site 30
S351
D
M
M
V
S
Y
S
S
T
S
D
F
P
S
S
Site 31
T352
M
M
V
S
Y
S
S
T
S
D
F
P
S
S
P
Site 32
S353
M
V
S
Y
S
S
T
S
D
F
P
S
S
P
W
Site 33
S357
S
S
T
S
D
F
P
S
S
P
W
D
W
I
G
Site 34
S358
S
T
S
D
F
P
S
S
P
W
D
W
I
G
L
Site 35
Y366
P
W
D
W
I
G
L
Y
K
V
G
L
R
D
V
Site 36
Y376
G
L
R
D
V
N
D
Y
V
S
Y
A
W
V
G
Site 37
Y379
D
V
N
D
Y
V
S
Y
A
W
V
G
D
S
K
Site 38
S385
S
Y
A
W
V
G
D
S
K
V
S
C
S
D
N
Site 39
S388
W
V
G
D
S
K
V
S
C
S
D
N
L
N
Q
Site 40
Y397
S
D
N
L
N
Q
V
Y
I
D
I
S
N
I
P
Site 41
T406
D
I
S
N
I
P
T
T
E
D
E
F
L
L
C
Site 42
Y414
E
D
E
F
L
L
C
Y
Y
S
N
S
L
R
S
Site 43
Y415
D
E
F
L
L
C
Y
Y
S
N
S
L
R
S
V
Site 44
S421
Y
Y
S
N
S
L
R
S
V
V
G
I
S
R
P
Site 45
S435
P
F
Q
I
P
P
G
S
L
R
E
D
P
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation