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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
COPS4
Full Name:
COP9 signalosome complex subunit 4
Alias:
COP9 constitutive photomorphogenic subunit 4; CSN4; JAB1-containing signalosome 4; SGN4; Signalosome 4; Signalosome subunit 4
Type:
Unknown function
Mass (Da):
46269
Number AA:
406
UniProt ID:
Q9BT78
International Prot ID:
IPI00171844
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0008180
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
D
L
A
Q
L
M
N
S
S
G
S
H
K
D
L
Site 2
S16
L
A
Q
L
M
N
S
S
G
S
H
K
D
L
A
Site 3
S18
Q
L
M
N
S
S
G
S
H
K
D
L
A
G
K
Site 4
S37
L
E
K
A
I
Q
L
S
G
A
E
Q
L
E
A
Site 5
T71
Q
L
L
T
D
F
C
T
H
L
P
N
L
P
D
Site 6
S79
H
L
P
N
L
P
D
S
T
A
K
E
I
Y
H
Site 7
S98
K
I
Q
P
R
V
I
S
F
E
E
Q
V
A
S
Site 8
S105
S
F
E
E
Q
V
A
S
I
R
Q
H
L
A
S
Site 9
S112
S
I
R
Q
H
L
A
S
I
Y
E
K
E
E
D
Site 10
Y114
R
Q
H
L
A
S
I
Y
E
K
E
E
D
W
R
Site 11
Y143
Q
K
Q
Y
N
V
D
Y
K
L
E
T
Y
L
K
Site 12
Y148
V
D
Y
K
L
E
T
Y
L
K
I
A
R
L
Y
Site 13
Y155
Y
L
K
I
A
R
L
Y
L
E
D
D
D
P
V
Site 14
Y167
D
P
V
Q
A
E
A
Y
I
N
R
A
S
L
L
Site 15
S172
E
A
Y
I
N
R
A
S
L
L
Q
N
E
S
T
Site 16
S178
A
S
L
L
Q
N
E
S
T
N
E
Q
L
Q
I
Site 17
T179
S
L
L
Q
N
E
S
T
N
E
Q
L
Q
I
H
Site 18
Y191
Q
I
H
Y
K
V
C
Y
A
R
V
L
D
Y
R
Site 19
Y197
C
Y
A
R
V
L
D
Y
R
R
K
F
I
E
A
Site 20
S212
A
Q
R
Y
N
E
L
S
Y
K
T
I
V
H
E
Site 21
S220
Y
K
T
I
V
H
E
S
E
R
L
E
A
L
K
Site 22
Y268
Y
G
I
L
E
K
M
Y
L
D
R
I
I
R
G
Site 23
T293
M
P
H
Q
K
A
T
T
A
D
G
S
S
I
L
Site 24
S311
V
I
E
H
N
L
L
S
A
S
K
L
Y
N
N
Site 25
T320
S
K
L
Y
N
N
I
T
F
E
E
L
G
A
L
Site 26
S340
A
K
A
E
K
I
A
S
Q
M
I
T
E
G
R
Site 27
T344
K
I
A
S
Q
M
I
T
E
G
R
M
N
G
F
Site 28
T369
E
T
R
E
A
L
P
T
W
D
K
Q
I
Q
S
Site 29
S389
N
N
L
L
E
K
I
S
Q
T
A
P
E
W
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation