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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SYT11
Full Name:
Synaptotagmin-11
Alias:
Synaptotagmin 12; Synaptotagmin XI; SYT12; SytXI
Type:
Mass (Da):
48306
Number AA:
431
UniProt ID:
Q9BT88
International Prot ID:
IPI00027875
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0008021
GO:0030672
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y53
K
K
Q
K
N
P
P
Y
K
F
I
H
M
L
K
Site 2
Y65
M
L
K
G
I
S
I
Y
P
E
T
L
S
N
K
Site 3
T68
G
I
S
I
Y
P
E
T
L
S
N
K
K
K
I
Site 4
S70
S
I
Y
P
E
T
L
S
N
K
K
K
I
I
K
Site 5
S105
A
A
E
A
G
L
L
S
R
D
K
D
P
R
G
Site 6
S114
D
K
D
P
R
G
P
S
S
G
S
C
I
D
Q
Site 7
S115
K
D
P
R
G
P
S
S
G
S
C
I
D
Q
L
Site 8
S117
P
R
G
P
S
S
G
S
C
I
D
Q
L
P
I
Site 9
Y128
Q
L
P
I
K
M
D
Y
G
E
E
L
R
S
P
Site 10
S134
D
Y
G
E
E
L
R
S
P
I
T
S
L
T
P
Site 11
S138
E
L
R
S
P
I
T
S
L
T
P
G
E
S
K
Site 12
T140
R
S
P
I
T
S
L
T
P
G
E
S
K
T
T
Site 13
S144
T
S
L
T
P
G
E
S
K
T
T
S
P
S
S
Site 14
T146
L
T
P
G
E
S
K
T
T
S
P
S
S
P
E
Site 15
T147
T
P
G
E
S
K
T
T
S
P
S
S
P
E
E
Site 16
S148
P
G
E
S
K
T
T
S
P
S
S
P
E
E
D
Site 17
S150
E
S
K
T
T
S
P
S
S
P
E
E
D
V
M
Site 18
S151
S
K
T
T
S
P
S
S
P
E
E
D
V
M
L
Site 19
Y167
S
L
T
F
S
V
D
Y
N
F
P
K
K
A
L
Site 20
T191
L
P
V
M
D
D
Q
T
Q
G
S
D
P
Y
I
Site 21
S194
M
D
D
Q
T
Q
G
S
D
P
Y
I
K
M
T
Site 22
Y197
Q
T
Q
G
S
D
P
Y
I
K
M
T
I
L
P
Site 23
T201
S
D
P
Y
I
K
M
T
I
L
P
D
K
R
H
Site 24
T212
D
K
R
H
R
V
K
T
R
V
L
R
K
T
L
Site 25
T218
K
T
R
V
L
R
K
T
L
D
P
V
F
D
E
Site 26
Y230
F
D
E
T
F
T
F
Y
G
I
P
Y
S
Q
L
Site 27
S253
V
L
S
F
D
R
F
S
R
D
D
V
I
G
E
Site 28
T272
L
A
G
V
D
P
S
T
G
K
V
Q
L
T
R
Site 29
S298
S
R
G
E
L
Q
V
S
L
S
Y
Q
P
V
A
Site 30
S300
G
E
L
Q
V
S
L
S
Y
Q
P
V
A
Q
R
Site 31
T309
Q
P
V
A
Q
R
M
T
V
V
V
L
K
A
R
Site 32
T324
H
L
P
K
M
D
I
T
G
L
S
G
N
P
Y
Site 33
Y331
T
G
L
S
G
N
P
Y
V
K
V
N
V
Y
Y
Site 34
Y337
P
Y
V
K
V
N
V
Y
Y
G
R
K
R
I
A
Site 35
Y338
Y
V
K
V
N
V
Y
Y
G
R
K
R
I
A
K
Site 36
T348
K
R
I
A
K
K
K
T
H
V
K
K
C
T
L
Site 37
T354
K
T
H
V
K
K
C
T
L
N
P
I
F
N
E
Site 38
T387
L
V
I
D
F
D
R
T
T
K
N
E
V
V
G
Site 39
T388
V
I
D
F
D
R
T
T
K
N
E
V
V
G
R
Site 40
S406
G
A
H
S
V
T
A
S
G
A
E
H
W
R
E
Site 41
S417
H
W
R
E
V
C
E
S
P
R
K
P
V
A
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation