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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTA3
Full Name:
Metastasis-associated protein MTA3
Alias:
KIAA1266; metastasis associated 1 family, member 3; metastasis associated family, member 3; metastasis associated gene family, member 3; metastasis-associated protein MTA3
Type:
Transcription protein, coactivator/corepressor
Mass (Da):
67504
Number AA:
594
UniProt ID:
Q9BTC8
International Prot ID:
IPI00165357
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0010468
GO:0019219
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
N
M
Y
R
V
G
D
Y
V
Y
F
E
N
S
S
Site 2
Y13
Y
R
V
G
D
Y
V
Y
F
E
N
S
S
S
N
Site 3
S19
V
Y
F
E
N
S
S
S
N
P
Y
L
I
R
R
Site 4
Y22
E
N
S
S
S
N
P
Y
L
I
R
R
I
E
E
Site 5
T33
R
I
E
E
L
N
K
T
A
S
G
N
V
E
A
Site 6
S35
E
E
L
N
K
T
A
S
G
N
V
E
A
K
V
Site 7
Y46
E
A
K
V
V
C
F
Y
R
R
R
D
I
S
N
Site 8
S52
F
Y
R
R
R
D
I
S
N
T
L
I
M
L
A
Site 9
T54
R
R
R
D
I
S
N
T
L
I
M
L
A
D
K
Site 10
T72
E
I
E
E
E
S
E
T
T
V
E
A
D
L
T
Site 11
T73
I
E
E
E
S
E
T
T
V
E
A
D
L
T
D
Site 12
T79
T
T
V
E
A
D
L
T
D
K
Q
K
H
Q
L
Site 13
S94
K
H
R
E
L
F
L
S
R
Q
Y
E
S
L
P
Site 14
Y97
E
L
F
L
S
R
Q
Y
E
S
L
P
A
T
H
Site 15
S99
F
L
S
R
Q
Y
E
S
L
P
A
T
H
I
R
Site 16
T103
Q
Y
E
S
L
P
A
T
H
I
R
G
K
C
S
Site 17
S119
A
L
L
N
E
T
E
S
V
L
S
Y
L
D
K
Site 18
S122
N
E
T
E
S
V
L
S
Y
L
D
K
E
D
T
Site 19
Y123
E
T
E
S
V
L
S
Y
L
D
K
E
D
T
F
Site 20
T129
S
Y
L
D
K
E
D
T
F
F
Y
S
L
V
Y
Site 21
S133
K
E
D
T
F
F
Y
S
L
V
Y
D
P
S
L
Site 22
Y156
E
I
R
V
G
P
R
Y
Q
A
D
I
P
E
M
Site 23
S169
E
M
L
L
E
G
E
S
D
E
R
E
Q
S
K
Site 24
S175
E
S
D
E
R
E
Q
S
K
L
E
V
K
V
W
Site 25
S186
V
K
V
W
D
P
N
S
P
L
T
D
R
Q
I
Site 26
T189
W
D
P
N
S
P
L
T
D
R
Q
I
D
Q
F
Site 27
S213
F
A
R
A
L
D
C
S
S
S
V
R
Q
P
S
Site 28
S214
A
R
A
L
D
C
S
S
S
V
R
Q
P
S
L
Site 29
S215
R
A
L
D
C
S
S
S
V
R
Q
P
S
L
H
Site 30
S220
S
S
S
V
R
Q
P
S
L
H
M
S
A
A
A
Site 31
S224
R
Q
P
S
L
H
M
S
A
A
A
A
S
R
D
Site 32
Y242
F
H
A
M
D
T
L
Y
R
H
S
Y
D
L
S
Site 33
S245
M
D
T
L
Y
R
H
S
Y
D
L
S
S
A
I
Site 34
Y246
D
T
L
Y
R
H
S
Y
D
L
S
S
A
I
S
Site 35
S272
R
D
E
M
E
E
W
S
A
S
E
A
S
L
F
Site 36
S274
E
M
E
E
W
S
A
S
E
A
S
L
F
E
E
Site 37
Y286
F
E
E
A
L
E
K
Y
G
K
D
F
N
D
I
Site 38
S302
Q
D
F
L
P
W
K
S
L
T
S
I
I
E
Y
Site 39
Y309
S
L
T
S
I
I
E
Y
Y
Y
M
W
K
T
T
Site 40
Y310
L
T
S
I
I
E
Y
Y
Y
M
W
K
T
T
D
Site 41
Y311
T
S
I
I
E
Y
Y
Y
M
W
K
T
T
D
R
Site 42
Y319
M
W
K
T
T
D
R
Y
V
Q
Q
K
R
L
K
Site 43
Y342
K
Q
V
Y
I
P
T
Y
S
K
P
N
P
N
Q
Site 44
S351
K
P
N
P
N
Q
I
S
T
S
N
G
K
P
G
Site 45
S353
N
P
N
Q
I
S
T
S
N
G
K
P
G
A
V
Site 46
T367
V
N
G
A
V
G
T
T
F
Q
P
Q
N
P
L
Site 47
S381
L
L
G
R
A
C
E
S
C
Y
A
T
Q
S
H
Site 48
S422
G
L
K
M
P
T
Q
S
E
E
E
K
L
S
P
Site 49
S428
Q
S
E
E
E
K
L
S
P
S
P
T
T
E
D
Site 50
S430
E
E
E
K
L
S
P
S
P
T
T
E
D
P
R
Site 51
T432
E
K
L
S
P
S
P
T
T
E
D
P
R
V
R
Site 52
T433
K
L
S
P
S
P
T
T
E
D
P
R
V
R
S
Site 53
S440
T
E
D
P
R
V
R
S
H
V
S
R
Q
A
M
Site 54
T455
Q
G
M
P
V
R
N
T
G
S
P
K
S
A
V
Site 55
S457
M
P
V
R
N
T
G
S
P
K
S
A
V
K
T
Site 56
S460
R
N
T
G
S
P
K
S
A
V
K
T
R
Q
A
Site 57
T464
S
P
K
S
A
V
K
T
R
Q
A
F
F
L
H
Site 58
Y474
A
F
F
L
H
T
T
Y
F
T
K
F
A
R
Q
Site 59
T486
A
R
Q
V
C
K
N
T
L
R
L
R
Q
A
A
Site 60
Y509
Y
A
A
I
R
A
E
Y
A
D
R
H
A
E
L
Site 61
S517
A
D
R
H
A
E
L
S
G
S
P
L
K
S
K
Site 62
S519
R
H
A
E
L
S
G
S
P
L
K
S
K
S
T
Site 63
S523
L
S
G
S
P
L
K
S
K
S
T
R
K
P
L
Site 64
S525
G
S
P
L
K
S
K
S
T
R
K
P
L
A
C
Site 65
S550
K
K
P
N
V
I
R
S
T
P
S
L
Q
T
P
Site 66
T551
K
P
N
V
I
R
S
T
P
S
L
Q
T
P
T
Site 67
T556
R
S
T
P
S
L
Q
T
P
T
T
K
R
M
L
Site 68
T559
P
S
L
Q
T
P
T
T
K
R
M
L
T
T
P
Site 69
T564
P
T
T
K
R
M
L
T
T
P
N
H
T
S
L
Site 70
T565
T
T
K
R
M
L
T
T
P
N
H
T
S
L
S
Site 71
S570
L
T
T
P
N
H
T
S
L
S
I
L
G
K
R
Site 72
S572
T
P
N
H
T
S
L
S
I
L
G
K
R
N
Y
Site 73
Y579
S
I
L
G
K
R
N
Y
S
H
H
N
G
L
D
Site 74
S580
I
L
G
K
R
N
Y
S
H
H
N
G
L
D
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation