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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRC1
Full Name:
Leucine-rich repeat-containing protein 1
Alias:
LANO adapter protein;LAP and no PDZ protein
Type:
Mass (Da):
59242
Number AA:
524
UniProt ID:
Q9BTT6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
R
C
N
R
H
V
E
S
I
D
K
R
H
C
S
Site 2
S23
S
I
D
K
R
H
C
S
L
V
Y
V
P
E
E
Site 3
Y26
K
R
H
C
S
L
V
Y
V
P
E
E
I
Y
R
Site 4
Y32
V
Y
V
P
E
E
I
Y
R
Y
A
R
S
L
E
Site 5
Y34
V
P
E
E
I
Y
R
Y
A
R
S
L
E
E
L
Site 6
S37
E
I
Y
R
Y
A
R
S
L
E
E
L
L
L
D
Site 7
S67
K
L
R
K
L
G
L
S
D
N
E
I
Q
R
L
Site 8
S90
Q
L
V
E
L
D
V
S
R
N
E
I
P
E
I
Site 9
T118
D
F
S
G
N
P
L
T
R
L
P
E
S
F
P
Site 10
S123
P
L
T
R
L
P
E
S
F
P
E
L
Q
N
L
Site 11
S139
C
L
S
V
N
D
I
S
L
Q
S
L
P
E
N
Site 12
S142
V
N
D
I
S
L
Q
S
L
P
E
N
I
G
N
Site 13
Y151
P
E
N
I
G
N
L
Y
N
L
A
S
L
E
L
Site 14
S155
G
N
L
Y
N
L
A
S
L
E
L
R
E
N
L
Site 15
T164
E
L
R
E
N
L
L
T
Y
L
P
D
S
L
T
Site 16
Y165
L
R
E
N
L
L
T
Y
L
P
D
S
L
T
Q
Site 17
T171
T
Y
L
P
D
S
L
T
Q
L
R
R
L
E
E
Site 18
Y187
D
L
G
N
N
E
I
Y
N
L
P
E
S
I
G
Site 19
S210
W
L
D
G
N
Q
L
S
E
L
P
Q
E
I
G
Site 20
S228
N
L
L
C
L
D
V
S
E
N
R
L
E
R
L
Site 21
S240
E
R
L
P
E
E
I
S
G
L
T
S
L
T
D
Site 22
T243
P
E
E
I
S
G
L
T
S
L
T
D
L
V
I
Site 23
T279
K
V
D
Q
N
R
L
T
Q
L
P
E
A
V
G
Site 24
T303
L
T
E
N
Q
L
L
T
L
P
K
S
I
G
K
Site 25
S307
Q
L
L
T
L
P
K
S
I
G
K
L
K
K
L
Site 26
S326
A
D
R
N
K
L
V
S
L
P
K
E
I
G
G
Site 27
T348
C
V
R
D
N
R
L
T
R
I
P
A
E
V
S
Site 28
S355
T
R
I
P
A
E
V
S
Q
A
T
E
L
H
V
Site 29
S388
K
L
K
A
L
W
L
S
D
N
Q
S
Q
P
L
Site 30
S392
L
W
L
S
D
N
Q
S
Q
P
L
L
T
F
Q
Site 31
T397
N
Q
S
Q
P
L
L
T
F
Q
T
D
T
D
Y
Site 32
T402
L
L
T
F
Q
T
D
T
D
Y
T
T
G
E
K
Site 33
Y404
T
F
Q
T
D
T
D
Y
T
T
G
E
K
I
L
Site 34
T406
Q
T
D
T
D
Y
T
T
G
E
K
I
L
T
C
Site 35
S443
E
N
L
V
N
D
V
S
D
E
A
W
N
E
R
Site 36
S456
E
R
A
V
N
R
V
S
A
I
R
F
V
E
D
Site 37
T472
K
D
E
E
D
N
E
T
R
T
L
L
R
R
A
Site 38
T480
R
T
L
L
R
R
A
T
P
H
P
G
E
L
K
Site 39
T492
E
L
K
H
M
K
K
T
V
E
N
L
R
N
D
Site 40
S508
N
A
A
K
G
L
D
S
N
K
N
E
V
N
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation