PhosphoNET

           
Protein Info 
   
Short Name:  TMEM43
Full Name:  Transmembrane protein 43
Alias:  FLJ00144 protein
Type: 
Mass (Da):  44858
Number AA:  400
UniProt ID:  Q9BTV4
International Prot ID:  IPI00301280
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005794  GO:0016020  GO:0016021 Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9AANYSSTSTRREHVK
Site 2T10ANYSSTSTRREHVKV
Site 3T19REHVKVKTSSQPGFL
Site 4S21HVKVKTSSQPGFLER
Site 5S30PGFLERLSETSGGMF
Site 6S79VSPDSIHSVAPENEG
Site 7S102LRTSKLLSDPNYGVH
Site 8Y122LRRHVEMYQWVETEE
Site 9S130QWVETEESREYTEDG
Site 10Y133ETEESREYTEDGQVK
Site 11T134TEESREYTEDGQVKK
Site 12S146VKKETRYSYNTEWRS
Site 13Y147KKETRYSYNTEWRSE
Site 14T149ETRYSYNTEWRSEII
Site 15S205DKVDNFKSLSLSKLE
Site 16S207VDNFKSLSLSKLEDP
Site 17S209NFKSLSLSKLEDPHV
Site 18Y226IRRGDFFYHSENPKY
Site 19S228RGDFFYHSENPKYPE
Site 20Y233YHSENPKYPEVGDLR
Site 21S244GDLRVSFSYAGLSGD
Site 22Y245DLRVSFSYAGLSGDD
Site 23S249SFSYAGLSGDDPDLG
Site 24S276GDQLVPFSTKSGDTL
Site 25S292LLHHGDFSAEEVFHR
Site 26S305HRELRSNSMKTWGLR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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