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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CABLES2
Full Name:
CDK5 and ABL1 enzyme substrate 2
Alias:
C20orf150; CABL2; Cdk5 and Abl enzyme substrate 2; DJ908M14.2; Ik3-2; Interactor with CDK3 2
Type:
Mass (Da):
52235
Number AA:
478
UniProt ID:
Q9BTV7
International Prot ID:
IPI00030512
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0016538
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0051301
GO:0051726
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
P
P
P
A
A
P
T
S
A
A
R
A
P
P
Q
Site 2
S42
A
L
R
R
R
G
D
S
R
R
R
Q
A
A
L
Site 3
S56
L
F
F
L
N
N
I
S
L
D
G
R
P
P
S
Site 4
S63
S
L
D
G
R
P
P
S
L
G
P
G
G
E
K
Site 5
T91
P
P
P
P
E
P
P
T
G
L
P
A
R
T
P
Site 6
T97
P
T
G
L
P
A
R
T
P
A
P
Q
G
L
L
Site 7
S105
P
A
P
Q
G
L
L
S
P
T
Q
V
P
T
G
Site 8
T107
P
Q
G
L
L
S
P
T
Q
V
P
T
G
L
G
Site 9
T125
Q
R
Q
R
K
R
V
T
S
Q
R
C
S
L
E
Site 10
S126
R
Q
R
K
R
V
T
S
Q
R
C
S
L
E
F
Site 11
S130
R
V
T
S
Q
R
C
S
L
E
F
L
E
D
A
Site 12
T146
G
C
A
P
A
Q
R
T
K
H
T
S
G
S
P
Site 13
S150
A
Q
R
T
K
H
T
S
G
S
P
R
H
K
G
Site 14
S152
R
T
K
H
T
S
G
S
P
R
H
K
G
L
K
Site 15
T161
R
H
K
G
L
K
K
T
H
F
I
K
N
M
R
Site 16
Y170
F
I
K
N
M
R
Q
Y
D
T
R
N
S
R
I
Site 17
S175
R
Q
Y
D
T
R
N
S
R
I
V
L
I
C
A
Site 18
S202
Y
G
E
G
L
R
I
S
D
L
R
V
D
S
Q
Site 19
S208
I
S
D
L
R
V
D
S
Q
K
Q
R
H
P
S
Site 20
S215
S
Q
K
Q
R
H
P
S
G
G
V
S
V
S
S
Site 21
S219
R
H
P
S
G
G
V
S
V
S
S
E
M
V
F
Site 22
S257
N
A
L
V
T
H
K
S
D
S
H
G
L
L
P
Site 23
T265
D
S
H
G
L
L
P
T
P
R
P
S
V
P
R
Site 24
S269
L
L
P
T
P
R
P
S
V
P
R
T
L
P
G
Site 25
T273
P
R
P
S
V
P
R
T
L
P
G
S
R
H
K
Site 26
S277
V
P
R
T
L
P
G
S
R
H
K
P
A
P
T
Site 27
S286
H
K
P
A
P
T
K
S
A
P
A
S
T
E
L
Site 28
S290
P
T
K
S
A
P
A
S
T
E
L
G
S
D
V
Site 29
S295
P
A
S
T
E
L
G
S
D
V
G
D
T
L
E
Site 30
T300
L
G
S
D
V
G
D
T
L
E
Y
N
P
N
L
Site 31
Y327
R
V
L
I
F
A
S
Y
M
T
T
V
I
E
Y
Site 32
Y334
Y
M
T
T
V
I
E
Y
V
K
P
S
D
L
K
Site 33
S338
V
I
E
Y
V
K
P
S
D
L
K
K
D
M
N
Site 34
T347
L
K
K
D
M
N
E
T
F
R
E
K
F
P
H
Site 35
T358
K
F
P
H
V
K
L
T
L
S
K
I
R
S
L
Site 36
S360
P
H
V
K
L
T
L
S
K
I
R
S
L
K
R
Site 37
S364
L
T
L
S
K
I
R
S
L
K
R
E
M
R
S
Site 38
S371
S
L
K
R
E
M
R
S
L
S
E
E
C
S
L
Site 39
S373
K
R
E
M
R
S
L
S
E
E
C
S
L
E
P
Site 40
S377
R
S
L
S
E
E
C
S
L
E
P
V
T
V
A
Site 41
S425
I
S
S
D
L
R
K
S
G
V
T
Q
L
I
D
Site 42
Y471
E
N
Q
V
L
P
H
Y
R
R
L
T
Q
Q
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation