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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FUCA2
Full Name:
Plasma alpha-L-fucosidase
Alias:
EC 3.2.1.51; FUCO2; Fucosidase, alpha-L- 2, plasma
Type:
Extracellular region protein
Mass (Da):
54061
Number AA:
467
UniProt ID:
Q9BTY2
International Prot ID:
IPI00012440
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0004560
GO:0043169
PhosphoSite+
KinaseNET
Biological Process:
GO:0006004
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
P
P
P
C
P
A
H
S
A
T
R
F
D
P
T
Site 2
T37
S
A
T
R
F
D
P
T
W
E
S
L
D
A
R
Site 3
Y86
Q
K
E
K
I
P
K
Y
V
E
F
M
K
D
N
Site 4
Y94
V
E
F
M
K
D
N
Y
P
P
S
F
K
Y
E
Site 5
Y100
N
Y
P
P
S
F
K
Y
E
D
F
G
P
L
F
Site 6
Y128
F
Q
A
S
G
A
K
Y
I
V
L
T
S
K
H
Site 7
T140
S
K
H
H
E
G
F
T
L
W
G
S
E
Y
S
Site 8
T173
E
V
A
I
R
N
R
T
D
L
R
F
G
L
Y
Site 9
Y181
D
L
R
F
G
L
Y
Y
S
L
F
E
W
F
H
Site 10
S197
L
F
L
E
D
E
S
S
S
F
H
K
R
Q
F
Site 11
S198
F
L
E
D
E
S
S
S
F
H
K
R
Q
F
P
Site 12
S207
H
K
R
Q
F
P
V
S
K
T
L
P
E
L
Y
Site 13
T209
R
Q
F
P
V
S
K
T
L
P
E
L
Y
E
L
Site 14
Y214
S
K
T
L
P
E
L
Y
E
L
V
N
N
Y
Q
Site 15
Y220
L
Y
E
L
V
N
N
Y
Q
P
E
V
L
W
S
Site 16
S227
Y
Q
P
E
V
L
W
S
D
G
D
G
G
A
P
Site 17
Y237
D
G
G
A
P
D
Q
Y
W
N
S
T
G
F
L
Site 18
Y248
T
G
F
L
A
W
L
Y
N
E
S
P
V
R
G
Site 19
T256
N
E
S
P
V
R
G
T
V
V
T
N
D
R
W
Site 20
T259
P
V
R
G
T
V
V
T
N
D
R
W
G
A
G
Site 21
Y281
F
Y
T
C
S
D
R
Y
N
P
G
H
L
L
P
Site 22
Y304
I
D
K
L
S
W
G
Y
R
R
E
A
G
I
S
Site 23
S311
Y
R
R
E
A
G
I
S
D
Y
L
T
I
E
E
Site 24
Y313
R
E
A
G
I
S
D
Y
L
T
I
E
E
L
V
Site 25
S358
E
R
L
R
Q
M
G
S
W
L
K
V
N
G
E
Site 26
Y368
K
V
N
G
E
A
I
Y
E
T
H
T
W
R
S
Site 27
T381
R
S
Q
N
D
T
V
T
P
D
V
W
Y
T
S
Site 28
Y386
T
V
T
P
D
V
W
Y
T
S
K
P
K
E
K
Site 29
S388
T
P
D
V
W
Y
T
S
K
P
K
E
K
L
V
Site 30
Y396
K
P
K
E
K
L
V
Y
A
I
F
L
K
W
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation