PhosphoNET

           
Protein Info 
   
Short Name:  MED18
Full Name:  Mediator of RNA polymerase II transcription subunit 18
Alias:  FLJ20045; Mediator 18; Mediator complex subunit 18; p28b
Type: 
Mass (Da):  23660
Number AA:  208
UniProt ID:  Q9BUE0
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016592  GO:0005634  GO:0032991 Uniprot OncoNet
Molecular Function:  GO:0016455  GO:0042802  GO:0042802 PhosphoSite+ KinaseNET
Biological Process:  GO:0006357  GO:0006350  GO:0006355 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S26MEYLLQGSVLDHSLE
Site 2S31QGSVLDHSLESLIHR
Site 3S34VLDHSLESLIHRLRG
Site 4S66LLKGQQASPFVLRAR
Site 5S75FVLRARRSMDRAGAP
Site 6Y87GAPWHLRYLGQPEMG
Site 7S159LVPGNTDSTEALSLS
Site 8T160VPGNTDSTEALSLSY
Site 9S183PAGQDMVSDDMKNFA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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