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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TUBB6
Full Name:
Tubulin beta-6 chain
Alias:
TBB6; Tubulin, beta-6
Type:
Cytoskeleton protein; Microtubule complex protein; Tubulin family.
Mass (Da):
49857
Number AA:
446
UniProt ID:
Q9BUF5
International Prot ID:
IPI00646779
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005874
GO:0043234
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
GO:0007018
GO:0051258
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y36
G
I
D
P
A
G
G
Y
V
G
D
S
A
L
Q
Site 2
Y50
Q
L
E
R
I
N
V
Y
Y
N
E
S
S
S
Q
Site 3
Y51
L
E
R
I
N
V
Y
Y
N
E
S
S
S
Q
K
Site 4
S56
V
Y
Y
N
E
S
S
S
Q
K
Y
V
P
R
A
Site 5
Y59
N
E
S
S
S
Q
K
Y
V
P
R
A
A
L
V
Site 6
T72
L
V
D
L
E
P
G
T
M
D
S
V
R
S
G
Site 7
S75
L
E
P
G
T
M
D
S
V
R
S
G
P
F
G
Site 8
S78
G
T
M
D
S
V
R
S
G
P
F
G
Q
L
F
Site 9
Y106
N
N
W
A
K
G
H
Y
T
E
G
A
E
L
V
Site 10
T107
N
W
A
K
G
H
Y
T
E
G
A
E
L
V
D
Site 11
S138
Q
G
F
Q
L
T
H
S
L
G
G
G
T
G
S
Site 12
T166
F
P
D
R
I
M
N
T
F
S
V
M
P
S
P
Site 13
S168
D
R
I
M
N
T
F
S
V
M
P
S
P
K
V
Site 14
S172
N
T
F
S
V
M
P
S
P
K
V
S
D
T
V
Site 15
S176
V
M
P
S
P
K
V
S
D
T
V
V
E
P
Y
Site 16
T178
P
S
P
K
V
S
D
T
V
V
E
P
Y
N
A
Site 17
Y183
S
D
T
V
V
E
P
Y
N
A
T
L
S
V
H
Site 18
S188
E
P
Y
N
A
T
L
S
V
H
Q
L
V
E
N
Site 19
T196
V
H
Q
L
V
E
N
T
D
E
T
Y
C
I
D
Site 20
T199
L
V
E
N
T
D
E
T
Y
C
I
D
N
E
A
Site 21
Y200
V
E
N
T
D
E
T
Y
C
I
D
N
E
A
L
Site 22
Y208
C
I
D
N
E
A
L
Y
D
I
C
F
R
T
L
Site 23
T218
C
F
R
T
L
K
L
T
T
P
T
Y
G
D
L
Site 24
T219
F
R
T
L
K
L
T
T
P
T
Y
G
D
L
N
Site 25
Y222
L
K
L
T
T
P
T
Y
G
D
L
N
H
L
V
Site 26
S230
G
D
L
N
H
L
V
S
A
T
M
S
G
V
T
Site 27
T232
L
N
H
L
V
S
A
T
M
S
G
V
T
T
S
Site 28
S234
H
L
V
S
A
T
M
S
G
V
T
T
S
L
R
Site 29
T237
S
A
T
M
S
G
V
T
T
S
L
R
F
P
G
Site 30
T238
A
T
M
S
G
V
T
T
S
L
R
F
P
G
Q
Site 31
S239
T
M
S
G
V
T
T
S
L
R
F
P
G
Q
L
Site 32
T274
M
P
G
F
A
P
L
T
S
R
G
S
Q
Q
Y
Site 33
S275
P
G
F
A
P
L
T
S
R
G
S
Q
Q
Y
R
Site 34
S278
A
P
L
T
S
R
G
S
Q
Q
Y
R
A
L
T
Site 35
Y281
T
S
R
G
S
Q
Q
Y
R
A
L
T
V
P
E
Site 36
T285
S
Q
Q
Y
R
A
L
T
V
P
E
L
T
Q
Q
Site 37
Y310
C
D
P
R
H
G
R
Y
L
T
V
A
T
V
F
Site 38
T312
P
R
H
G
R
Y
L
T
V
A
T
V
F
R
G
Site 39
T315
G
R
Y
L
T
V
A
T
V
F
R
G
P
M
S
Site 40
S322
T
V
F
R
G
P
M
S
M
K
E
V
D
E
Q
Site 41
S335
E
Q
M
L
A
I
Q
S
K
N
S
S
Y
F
V
Site 42
S338
L
A
I
Q
S
K
N
S
S
Y
F
V
E
W
I
Site 43
S339
A
I
Q
S
K
N
S
S
Y
F
V
E
W
I
P
Site 44
Y340
I
Q
S
K
N
S
S
Y
F
V
E
W
I
P
N
Site 45
T366
R
G
L
K
M
A
S
T
F
I
G
N
S
T
A
Site 46
S382
Q
E
L
F
K
R
I
S
E
Q
F
S
A
M
F
Site 47
S386
K
R
I
S
E
Q
F
S
A
M
F
R
R
K
A
Site 48
Y425
L
V
S
E
Y
Q
Q
Y
Q
D
A
T
A
N
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation