KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
WRAP53
Full Name:
Telomerase Cajal body protein 1
Alias:
FLJ10385; TCAB1; Telomerase cajal body protein 1; Telomerase Cajal body protein 1: WD repeat-containing protein 79: WD40 repeats-containing protein encoding RNA antisense to p53; WD repeat containing, antisense to TP53; WD repeat-containing protein 79; WDR79
Type:
Mass (Da):
59309
Number AA:
548
UniProt ID:
Q9BUR4
International Prot ID:
IPI00306087
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015030
GO:0005697
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0051973
GO:0032203
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
L
A
P
D
C
C
P
S
D
Q
D
P
A
P
A
Site 2
S26
D
P
A
P
A
H
P
S
P
H
A
S
P
M
N
Site 3
S30
A
H
P
S
P
H
A
S
P
M
N
K
N
A
D
Site 4
S38
P
M
N
K
N
A
D
S
E
L
M
P
P
P
P
Site 5
S54
R
G
D
P
P
R
L
S
P
D
P
V
A
G
S
Site 6
S61
S
P
D
P
V
A
G
S
A
V
S
Q
E
L
R
Site 7
S64
P
V
A
G
S
A
V
S
Q
E
L
R
E
G
D
Site 8
S74
L
R
E
G
D
P
V
S
L
S
T
P
L
E
T
Site 9
S76
E
G
D
P
V
S
L
S
T
P
L
E
T
E
F
Site 10
T77
G
D
P
V
S
L
S
T
P
L
E
T
E
F
G
Site 11
T81
S
L
S
T
P
L
E
T
E
F
G
S
P
S
E
Site 12
S85
P
L
E
T
E
F
G
S
P
S
E
L
S
P
R
Site 13
S87
E
T
E
F
G
S
P
S
E
L
S
P
R
I
E
Site 14
S90
F
G
S
P
S
E
L
S
P
R
I
E
E
Q
E
Site 15
S99
R
I
E
E
Q
E
L
S
E
N
T
S
L
P
A
Site 16
S103
Q
E
L
S
E
N
T
S
L
P
A
E
E
A
N
Site 17
S112
P
A
E
E
A
N
G
S
L
S
E
E
E
A
N
Site 18
S114
E
E
A
N
G
S
L
S
E
E
E
A
N
G
P
Site 19
S133
G
K
A
M
E
D
T
S
G
E
P
A
A
E
D
Site 20
Y148
E
G
D
T
A
W
N
Y
S
F
S
Q
L
P
R
Site 21
S149
G
D
T
A
W
N
Y
S
F
S
Q
L
P
R
F
Site 22
S151
T
A
W
N
Y
S
F
S
Q
L
P
R
F
L
S
Site 23
S158
S
Q
L
P
R
F
L
S
G
S
W
S
E
F
S
Site 24
S160
L
P
R
F
L
S
G
S
W
S
E
F
S
T
Q
Site 25
S162
R
F
L
S
G
S
W
S
E
F
S
T
Q
P
E
Site 26
S165
S
G
S
W
S
E
F
S
T
Q
P
E
N
F
L
Site 27
T166
G
S
W
S
E
F
S
T
Q
P
E
N
F
L
K
Site 28
Y196
A
D
N
I
L
R
I
Y
N
L
P
P
E
L
Y
Site 29
Y203
Y
N
L
P
P
E
L
Y
H
E
G
E
Q
V
E
Site 30
Y211
H
E
G
E
Q
V
E
Y
A
E
M
V
P
V
L
Site 31
Y227
M
V
E
G
D
T
I
Y
D
Y
C
W
Y
S
L
Site 32
Y229
E
G
D
T
I
Y
D
Y
C
W
Y
S
L
M
S
Site 33
Y232
T
I
Y
D
Y
C
W
Y
S
L
M
S
S
A
Q
Site 34
T242
M
S
S
A
Q
P
D
T
S
Y
V
A
S
S
S
Site 35
S243
S
S
A
Q
P
D
T
S
Y
V
A
S
S
S
R
Site 36
Y244
S
A
Q
P
D
T
S
Y
V
A
S
S
S
R
E
Site 37
S247
P
D
T
S
Y
V
A
S
S
S
R
E
N
P
I
Site 38
S248
D
T
S
Y
V
A
S
S
S
R
E
N
P
I
H
Site 39
S249
T
S
Y
V
A
S
S
S
R
E
N
P
I
H
I
Site 40
S267
F
T
G
E
L
R
A
S
F
R
A
Y
N
H
L
Site 41
Y271
L
R
A
S
F
R
A
Y
N
H
L
D
E
L
T
Site 42
T278
Y
N
H
L
D
E
L
T
A
A
H
S
L
C
F
Site 43
S282
D
E
L
T
A
A
H
S
L
C
F
S
P
D
G
Site 44
S304
N
R
T
V
R
V
F
S
T
A
R
P
G
R
D
Site 45
T305
R
T
V
R
V
F
S
T
A
R
P
G
R
D
C
Site 46
T317
R
D
C
E
V
R
A
T
F
A
K
K
Q
G
Q
Site 47
Y340
F
S
P
A
Q
P
L
Y
A
C
G
S
Y
G
R
Site 48
S344
Q
P
L
Y
A
C
G
S
Y
G
R
S
L
G
L
Site 49
S348
A
C
G
S
Y
G
R
S
L
G
L
Y
A
W
D
Site 50
Y352
Y
G
R
S
L
G
L
Y
A
W
D
D
G
S
P
Site 51
T371
G
G
H
Q
G
G
I
T
H
L
C
F
H
P
D
Site 52
S384
P
D
G
N
R
F
F
S
G
A
R
K
D
A
E
Site 53
Y402
W
D
L
R
Q
S
G
Y
P
L
W
S
L
G
R
Site 54
S406
Q
S
G
Y
P
L
W
S
L
G
R
E
V
T
T
Site 55
T412
W
S
L
G
R
E
V
T
T
N
Q
R
I
Y
F
Site 56
Y418
V
T
T
N
Q
R
I
Y
F
D
L
D
P
T
G
Site 57
S438
G
S
T
S
G
A
V
S
V
W
D
T
D
G
P
Site 58
T442
G
A
V
S
V
W
D
T
D
G
P
G
N
D
G
Site 59
S456
G
K
P
E
P
V
L
S
F
L
P
Q
K
D
C
Site 60
T464
F
L
P
Q
K
D
C
T
N
G
V
S
L
H
P
Site 61
S468
K
D
C
T
N
G
V
S
L
H
P
S
L
P
L
Site 62
T489
Q
R
V
F
P
E
P
T
E
S
G
D
E
G
E
Site 63
S491
V
F
P
E
P
T
E
S
G
D
E
G
E
E
L
Site 64
S525
W
C
G
G
A
P
D
S
S
I
P
D
D
H
Q
Site 65
S526
C
G
G
A
P
D
S
S
I
P
D
D
H
Q
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation