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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FICD
Full Name:
Adenosine monophosphate-protein transferase FICD
Alias:
AMPylator FICD;FIC domain-containing protein;Huntingtin yeast partner E;Huntingtin-interacting protein 13;Huntingtin-interacting protein E
Type:
Mass (Da):
51778
Number AA:
458
UniProt ID:
Q9BVA6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S63
K
G
L
Y
L
L
R
S
K
P
D
R
A
Q
H
Site 2
T73
D
R
A
Q
H
A
A
T
K
C
T
S
P
S
T
Site 3
S77
H
A
A
T
K
C
T
S
P
S
T
E
L
S
I
Site 4
S79
A
T
K
C
T
S
P
S
T
E
L
S
I
T
S
Site 5
T80
T
K
C
T
S
P
S
T
E
L
S
I
T
S
R
Site 6
S83
T
S
P
S
T
E
L
S
I
T
S
R
G
A
T
Site 7
S99
L
V
A
K
T
K
A
S
P
A
G
K
L
E
A
Site 8
Y161
K
D
I
I
Q
A
D
Y
L
Y
T
R
A
L
T
Site 9
T168
Y
L
Y
T
R
A
L
T
I
S
P
Y
H
E
K
Site 10
S170
Y
T
R
A
L
T
I
S
P
Y
H
E
K
A
L
Site 11
Y172
R
A
L
T
I
S
P
Y
H
E
K
A
L
V
N
Site 12
Y194
V
E
E
I
D
Q
R
Y
F
S
I
I
D
S
K
Site 13
S196
E
I
D
Q
R
Y
F
S
I
I
D
S
K
V
K
Site 14
S200
R
Y
F
S
I
I
D
S
K
V
K
K
V
M
S
Site 15
S207
S
K
V
K
K
V
M
S
I
P
K
G
N
S
A
Site 16
Y223
R
R
V
M
E
E
T
Y
Y
H
H
I
Y
H
T
Site 17
Y224
R
V
M
E
E
T
Y
Y
H
H
I
Y
H
T
V
Site 18
Y228
E
T
Y
Y
H
H
I
Y
H
T
V
A
I
E
G
Site 19
S241
E
G
N
T
L
T
L
S
E
I
R
H
I
L
E
Site 20
T249
E
I
R
H
I
L
E
T
R
Y
A
V
P
G
K
Site 21
Y251
R
H
I
L
E
T
R
Y
A
V
P
G
K
S
L
Site 22
S257
R
Y
A
V
P
G
K
S
L
E
E
Q
N
E
V
Site 23
T276
A
A
M
K
Y
I
N
T
T
L
V
S
R
I
G
Site 24
T286
V
S
R
I
G
S
V
T
I
S
D
V
L
E
I
Site 25
Y300
I
H
R
R
V
L
G
Y
V
D
P
V
E
A
G
Site 26
T311
V
E
A
G
R
F
R
T
T
Q
V
L
V
G
H
Site 27
T312
E
A
G
R
F
R
T
T
Q
V
L
V
G
H
H
Site 28
S373
I
D
G
N
G
R
T
S
R
L
L
M
N
L
I
Site 29
T390
Q
A
G
Y
P
P
I
T
I
R
K
E
Q
R
S
Site 30
S397
T
I
R
K
E
Q
R
S
D
Y
Y
H
V
L
E
Site 31
Y399
R
K
E
Q
R
S
D
Y
Y
H
V
L
E
A
A
Site 32
Y400
K
E
Q
R
S
D
Y
Y
H
V
L
E
A
A
N
Site 33
T453
N
H
S
G
F
K
E
T
L
P
V
K
P
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation