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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PHF20
Full Name:
PHD finger protein 20
Alias:
C20orf104; DJ1121G12.1; GLEA2; Glioma-expressed antigen 2; HCA58; Hepatocellular carcinoma-associated antigen 58; Novel zinc finger; NZF; PHD finger pro
Type:
Unknown function
Mass (Da):
115386
Number AA:
1012
UniProt ID:
Q9BVI0
International Prot ID:
IPI00074876
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
P
P
N
R
R
G
I
S
F
E
V
G
A
Q
L
Site 2
Y29
R
D
R
L
K
N
W
Y
P
A
H
I
E
D
I
Site 3
Y38
A
H
I
E
D
I
D
Y
E
E
G
K
V
L
I
Site 4
Y64
W
F
C
W
D
S
P
Y
L
R
P
L
E
K
I
Site 5
S84
G
L
H
E
E
D
G
S
S
E
F
Q
I
N
E
Site 6
S85
L
H
E
E
D
G
S
S
E
F
Q
I
N
E
Q
Site 7
Y103
C
W
S
D
C
R
F
Y
P
A
K
V
T
A
V
Site 8
T115
T
A
V
N
K
D
G
T
Y
T
V
K
F
Y
D
Site 9
Y116
A
V
N
K
D
G
T
Y
T
V
K
F
Y
D
G
Site 10
T117
V
N
K
D
G
T
Y
T
V
K
F
Y
D
G
V
Site 11
T151
G
N
A
R
P
K
E
T
D
H
K
S
L
S
S
Site 12
S155
P
K
E
T
D
H
K
S
L
S
S
S
P
D
K
Site 13
S157
E
T
D
H
K
S
L
S
S
S
P
D
K
R
E
Site 14
S158
T
D
H
K
S
L
S
S
S
P
D
K
R
E
K
Site 15
S159
D
H
K
S
L
S
S
S
P
D
K
R
E
K
F
Site 16
T173
F
K
E
Q
R
K
A
T
V
N
V
K
K
D
K
Site 17
T187
K
E
D
K
P
L
K
T
E
K
R
P
K
Q
P
Site 18
S203
K
E
G
K
L
I
C
S
E
K
G
K
V
S
E
Site 19
S209
C
S
E
K
G
K
V
S
E
K
S
L
P
K
N
Site 20
S212
K
G
K
V
S
E
K
S
L
P
K
N
E
K
E
Site 21
S225
K
E
D
K
E
N
I
S
E
N
D
R
E
Y
S
Site 22
Y231
I
S
E
N
D
R
E
Y
S
G
D
A
Q
V
D
Site 23
S232
S
E
N
D
R
E
Y
S
G
D
A
Q
V
D
K
Site 24
S248
P
E
N
D
I
V
K
S
P
Q
E
N
L
R
E
Site 25
S265
R
K
R
G
R
P
P
S
I
A
P
T
A
V
D
Site 26
T269
R
P
P
S
I
A
P
T
A
V
D
S
N
S
Q
Site 27
S273
I
A
P
T
A
V
D
S
N
S
Q
T
L
Q
P
Site 28
S275
P
T
A
V
D
S
N
S
Q
T
L
Q
P
I
T
Site 29
T277
A
V
D
S
N
S
Q
T
L
Q
P
I
T
L
E
Site 30
T282
S
Q
T
L
Q
P
I
T
L
E
L
R
R
R
K
Site 31
S291
E
L
R
R
R
K
I
S
K
G
C
E
V
P
L
Site 32
S307
R
P
R
L
D
K
N
S
S
Q
E
K
S
K
N
Site 33
S308
P
R
L
D
K
N
S
S
Q
E
K
S
K
N
Y
Site 34
S312
K
N
S
S
Q
E
K
S
K
N
Y
S
E
N
T
Site 35
S316
Q
E
K
S
K
N
Y
S
E
N
T
D
K
D
L
Site 36
S324
E
N
T
D
K
D
L
S
R
R
R
S
S
R
L
Site 37
S328
K
D
L
S
R
R
R
S
S
R
L
S
T
N
G
Site 38
S329
D
L
S
R
R
R
S
S
R
L
S
T
N
G
T
Site 39
S332
R
R
R
S
S
R
L
S
T
N
G
T
H
E
I
Site 40
T333
R
R
S
S
R
L
S
T
N
G
T
H
E
I
L
Site 41
T336
S
R
L
S
T
N
G
T
H
E
I
L
D
P
D
Site 42
S347
L
D
P
D
L
V
V
S
D
L
V
D
T
D
P
Site 43
T358
D
T
D
P
L
Q
D
T
L
S
S
T
K
E
S
Site 44
S360
D
P
L
Q
D
T
L
S
S
T
K
E
S
E
E
Site 45
S361
P
L
Q
D
T
L
S
S
T
K
E
S
E
E
G
Site 46
S365
T
L
S
S
T
K
E
S
E
E
G
Q
L
K
S
Site 47
S372
S
E
E
G
Q
L
K
S
A
L
E
A
G
Q
V
Site 48
T384
G
Q
V
S
S
A
L
T
C
H
S
F
G
D
G
Site 49
S387
S
S
A
L
T
C
H
S
F
G
D
G
S
G
A
Site 50
T408
C
P
S
M
G
E
N
T
M
K
T
E
P
T
S
Site 51
T411
M
G
E
N
T
M
K
T
E
P
T
S
P
L
V
Site 52
S415
T
M
K
T
E
P
T
S
P
L
V
E
L
Q
E
Site 53
S424
L
V
E
L
Q
E
I
S
T
V
E
V
T
N
T
Site 54
T431
S
T
V
E
V
T
N
T
F
K
K
T
D
D
F
Site 55
T435
V
T
N
T
F
K
K
T
D
D
F
G
S
S
N
Site 56
Y471
R
K
A
K
L
L
H
Y
H
M
K
Y
F
H
G
Site 57
Y475
L
L
H
Y
H
M
K
Y
F
H
G
M
E
K
S
Site 58
S482
Y
F
H
G
M
E
K
S
L
E
P
E
E
S
P
Site 59
S488
K
S
L
E
P
E
E
S
P
G
K
R
H
V
Q
Site 60
T496
P
G
K
R
H
V
Q
T
R
G
P
S
A
S
D
Site 61
S500
H
V
Q
T
R
G
P
S
A
S
D
K
P
S
Q
Site 62
S502
Q
T
R
G
P
S
A
S
D
K
P
S
Q
E
T
Site 63
S506
P
S
A
S
D
K
P
S
Q
E
T
L
T
R
K
Site 64
T511
K
P
S
Q
E
T
L
T
R
K
R
V
S
A
S
Site 65
S516
T
L
T
R
K
R
V
S
A
S
S
P
T
T
K
Site 66
S519
R
K
R
V
S
A
S
S
P
T
T
K
D
K
E
Site 67
T522
V
S
A
S
S
P
T
T
K
D
K
E
K
N
K
Site 68
T551
K
K
K
K
K
K
K
T
K
P
E
C
P
C
S
Site 69
S558
T
K
P
E
C
P
C
S
E
E
I
S
D
T
S
Site 70
S562
C
P
C
S
E
E
I
S
D
T
S
Q
E
P
S
Site 71
T564
C
S
E
E
I
S
D
T
S
Q
E
P
S
P
P
Site 72
S565
S
E
E
I
S
D
T
S
Q
E
P
S
P
P
K
Site 73
S569
S
D
T
S
Q
E
P
S
P
P
K
A
F
A
V
Site 74
T577
P
P
K
A
F
A
V
T
R
C
G
S
S
H
K
Site 75
S581
F
A
V
T
R
C
G
S
S
H
K
P
G
V
H
Site 76
S582
A
V
T
R
C
G
S
S
H
K
P
G
V
H
M
Site 77
S590
H
K
P
G
V
H
M
S
P
Q
L
H
G
P
E
Site 78
S598
P
Q
L
H
G
P
E
S
G
H
H
K
G
K
V
Site 79
S614
A
L
E
E
D
N
L
S
E
S
S
S
E
S
F
Site 80
S616
E
E
D
N
L
S
E
S
S
S
E
S
F
L
W
Site 81
S617
E
D
N
L
S
E
S
S
S
E
S
F
L
W
S
Site 82
S618
D
N
L
S
E
S
S
S
E
S
F
L
W
S
D
Site 83
S620
L
S
E
S
S
S
E
S
F
L
W
S
D
D
E
Site 84
S624
S
S
E
S
F
L
W
S
D
D
E
Y
G
Q
D
Site 85
Y628
F
L
W
S
D
D
E
Y
G
Q
D
V
D
V
T
Site 86
T635
Y
G
Q
D
V
D
V
T
T
N
P
D
E
E
L
Site 87
T636
G
Q
D
V
D
V
T
T
N
P
D
E
E
L
D
Site 88
Y648
E
L
D
G
D
D
R
Y
D
F
E
V
V
R
C
Site 89
Y692
E
E
N
V
P
E
K
Y
T
C
Y
V
C
Q
D
Site 90
Y695
V
P
E
K
Y
T
C
Y
V
C
Q
D
P
P
G
Site 91
Y709
G
Q
R
P
G
F
K
Y
W
Y
D
K
E
W
L
Site 92
Y711
R
P
G
F
K
Y
W
Y
D
K
E
W
L
S
R
Site 93
S732
A
F
L
E
E
N
Y
S
H
Q
N
A
K
K
I
Site 94
S764
H
G
L
Q
L
K
M
S
I
L
Q
S
R
E
H
Site 95
S768
L
K
M
S
I
L
Q
S
R
E
H
P
D
L
P
Site 96
S790
Q
H
S
G
E
G
R
S
H
F
R
N
I
P
V
Site 97
T798
H
F
R
N
I
P
V
T
D
T
R
S
K
E
E
Site 98
S802
I
P
V
T
D
T
R
S
K
E
E
A
P
S
Y
Site 99
S808
R
S
K
E
E
A
P
S
Y
R
T
L
N
G
A
Site 100
Y809
S
K
E
E
A
P
S
Y
R
T
L
N
G
A
V
Site 101
S833
L
P
R
S
V
E
E
S
Y
I
T
S
E
H
C
Site 102
Y834
P
R
S
V
E
E
S
Y
I
T
S
E
H
C
Y
Site 103
T836
S
V
E
E
S
Y
I
T
S
E
H
C
Y
Q
K
Site 104
Y841
Y
I
T
S
E
H
C
Y
Q
K
P
R
A
Y
Y
Site 105
Y847
C
Y
Q
K
P
R
A
Y
Y
P
A
V
E
Q
K
Site 106
Y848
Y
Q
K
P
R
A
Y
Y
P
A
V
E
Q
K
L
Site 107
S878
L
H
E
N
G
D
D
S
L
S
P
R
L
G
W
Site 108
S880
E
N
G
D
D
S
L
S
P
R
L
G
W
P
L
Site 109
S892
W
P
L
D
Q
D
R
S
K
G
D
S
D
P
K
Site 110
S896
Q
D
R
S
K
G
D
S
D
P
K
P
G
S
P
Site 111
S902
D
S
D
P
K
P
G
S
P
K
V
K
E
Y
V
Site 112
Y908
G
S
P
K
V
K
E
Y
V
S
K
K
A
L
P
Site 113
S910
P
K
V
K
E
Y
V
S
K
K
A
L
P
E
E
Site 114
S933
R
G
G
E
G
L
L
S
S
Q
H
Q
W
Q
F
Site 115
S934
G
G
E
G
L
L
S
S
Q
H
Q
W
Q
F
N
Site 116
T944
Q
W
Q
F
N
L
L
T
H
V
E
S
L
Q
D
Site 117
S948
N
L
L
T
H
V
E
S
L
Q
D
E
V
T
H
Site 118
T954
E
S
L
Q
D
E
V
T
H
R
M
D
S
I
E
Site 119
S959
E
V
T
H
R
M
D
S
I
E
K
E
L
D
V
Site 120
S969
K
E
L
D
V
L
E
S
W
L
D
Y
T
G
E
Site 121
Y973
V
L
E
S
W
L
D
Y
T
G
E
L
E
P
P
Site 122
T974
L
E
S
W
L
D
Y
T
G
E
L
E
P
P
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation