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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NUDT9
Full Name:
ADP-ribose pyrophosphatase, mitochondrial
Alias:
Adenosine diphosphoribose pyrophosphatase; ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ADP-ribose pyrophosphatase, mitochondrial; ADPR-PPase; MGC3037; Nucleoside diphosphate-linked moiety X motif 9; Nudix (nucleoside diphosphate linked moiety X)-type motif 9; Nudix motif 9; NUDT10; PSEC0099
Type:
Mitochondrial; Hydrolase; EC 3.6.1.13; Nucleotide Metabolism - purine
Mass (Da):
39125
Number AA:
350
UniProt ID:
Q9BW91
International Prot ID:
IPI00031558
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005739
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0000287
GO:0003824
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006163
GO:0006195
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
L
A
S
V
T
I
R
S
S
R
C
R
G
I
Q
Site 2
S27
A
S
V
T
I
R
S
S
R
C
R
G
I
Q
A
Site 3
S38
G
I
Q
A
F
R
N
S
F
S
S
S
W
F
H
Site 4
S40
Q
A
F
R
N
S
F
S
S
S
W
F
H
L
N
Site 5
S54
N
T
N
V
M
S
G
S
N
G
S
K
E
N
S
Site 6
S57
V
M
S
G
S
N
G
S
K
E
N
S
H
N
K
Site 7
S61
S
N
G
S
K
E
N
S
H
N
K
A
R
T
S
Site 8
T67
N
S
H
N
K
A
R
T
S
P
Y
P
G
S
K
Site 9
S68
S
H
N
K
A
R
T
S
P
Y
P
G
S
K
V
Site 10
S73
R
T
S
P
Y
P
G
S
K
V
E
R
S
Q
V
Site 11
S78
P
G
S
K
V
E
R
S
Q
V
P
N
E
K
V
Site 12
Y94
W
L
V
E
W
Q
D
Y
K
P
V
E
Y
T
A
Site 13
Y99
Q
D
Y
K
P
V
E
Y
T
A
V
S
V
L
A
Site 14
S116
R
W
A
D
P
Q
I
S
E
S
N
F
S
P
K
Site 15
S118
A
D
P
Q
I
S
E
S
N
F
S
P
K
F
N
Site 16
S121
Q
I
S
E
S
N
F
S
P
K
F
N
E
K
D
Site 17
S135
D
G
H
V
E
R
K
S
K
N
G
L
Y
E
I
Site 18
Y140
R
K
S
K
N
G
L
Y
E
I
E
N
G
R
P
Site 19
S183
T
R
W
K
R
D
S
S
G
N
K
I
M
H
P
Site 20
T226
P
G
E
K
I
S
A
T
L
K
R
E
F
G
E
Site 21
S238
F
G
E
E
A
L
N
S
L
Q
K
T
S
A
E
Site 22
T242
A
L
N
S
L
Q
K
T
S
A
E
K
R
E
I
Site 23
S258
E
K
L
H
K
L
F
S
Q
D
H
L
V
I
Y
Site 24
Y265
S
Q
D
H
L
V
I
Y
K
G
Y
V
D
D
P
Site 25
Y268
H
L
V
I
Y
K
G
Y
V
D
D
P
R
N
T
Site 26
Y287
M
E
T
E
A
V
N
Y
H
D
E
T
G
E
I
Site 27
T291
A
V
N
Y
H
D
E
T
G
E
I
M
D
N
L
Site 28
Y321
I
N
D
K
L
K
L
Y
A
S
H
S
Q
F
I
Site 29
S323
D
K
L
K
L
Y
A
S
H
S
Q
F
I
K
L
Site 30
S340
E
K
R
D
A
H
W
S
E
D
S
E
A
D
C
Site 31
S343
D
A
H
W
S
E
D
S
E
A
D
C
H
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation