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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TARS2
Full Name:
Threonyl-tRNA synthetase, mitochondrial
Alias:
EC 6.1.1.3; Flj12528; Sytm; Tars2; Tars2 protein; Tarsl1; Threonyl-trna synthetase; Threonyl-trna synthetase 2, mitochondrial; Threonyl-trna synthetase-like 1 variant
Type:
Cytoplasm, Mitochondrial matrix, Mitochondrion protein
Mass (Da):
81036
Number AA:
718
UniProt ID:
Q9BW92
International Prot ID:
IPI00604527
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004829
PhosphoSite+
KinaseNET
Biological Process:
GO:0006435
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S52
A
Q
V
K
R
L
A
S
M
A
Q
K
E
P
R
Site 2
T60
M
A
Q
K
E
P
R
T
I
K
I
S
L
P
G
Site 3
S64
E
P
R
T
I
K
I
S
L
P
G
G
Q
K
I
Site 4
T79
D
A
V
A
W
N
T
T
P
Y
Q
L
A
R
Q
Site 5
S88
Y
Q
L
A
R
Q
I
S
S
T
L
A
D
T
A
Site 6
S115
E
R
P
L
E
T
D
S
D
L
R
F
L
T
F
Site 7
T121
D
S
D
L
R
F
L
T
F
D
S
P
E
G
K
Site 8
S156
A
V
L
C
R
G
P
S
T
E
Y
G
F
Y
H
Site 9
T157
V
L
C
R
G
P
S
T
E
Y
G
F
Y
H
D
Site 10
Y162
P
S
T
E
Y
G
F
Y
H
D
F
F
L
G
K
Site 11
T172
F
F
L
G
K
E
R
T
I
R
G
S
E
L
P
Site 12
S176
K
E
R
T
I
R
G
S
E
L
P
V
L
E
R
Site 13
T189
E
R
I
C
Q
E
L
T
A
A
A
R
P
F
R
Site 14
S201
P
F
R
R
L
E
A
S
R
D
Q
L
R
Q
L
Site 15
T224
H
L
I
E
E
K
V
T
G
P
T
A
T
V
Y
Site 16
T248
Q
G
P
H
L
R
H
T
G
Q
I
G
G
L
K
Site 17
S258
I
G
G
L
K
L
L
S
N
S
S
S
L
W
R
Site 18
S260
G
L
K
L
L
S
N
S
S
S
L
W
R
S
S
Site 19
S261
L
K
L
L
S
N
S
S
S
L
W
R
S
S
G
Site 20
S262
K
L
L
S
N
S
S
S
L
W
R
S
S
G
A
Site 21
S266
N
S
S
S
L
W
R
S
S
G
A
P
E
T
L
Site 22
S267
S
S
S
L
W
R
S
S
G
A
P
E
T
L
Q
Site 23
T272
R
S
S
G
A
P
E
T
L
Q
R
V
S
G
I
Site 24
S277
P
E
T
L
Q
R
V
S
G
I
S
F
P
T
T
Site 25
T284
S
G
I
S
F
P
T
T
E
L
L
R
V
W
E
Site 26
S321
F
H
E
L
S
P
G
S
C
F
F
L
P
R
G
Site 27
Y332
L
P
R
G
T
R
V
Y
N
A
L
V
A
F
I
Site 28
Y343
V
A
F
I
R
A
E
Y
A
H
R
G
F
S
E
Site 29
S349
E
Y
A
H
R
G
F
S
E
V
K
T
P
T
L
Site 30
T353
R
G
F
S
E
V
K
T
P
T
L
F
S
T
K
Site 31
S383
F
A
V
Q
P
P
G
S
D
R
P
P
S
S
Q
Site 32
S388
P
G
S
D
R
P
P
S
S
Q
S
D
D
S
T
Site 33
S389
G
S
D
R
P
P
S
S
Q
S
D
D
S
T
R
Site 34
S391
D
R
P
P
S
S
Q
S
D
D
S
T
R
H
I
Site 35
S394
P
S
S
Q
S
D
D
S
T
R
H
I
T
D
T
Site 36
T395
S
S
Q
S
D
D
S
T
R
H
I
T
D
T
L
Site 37
T399
D
D
S
T
R
H
I
T
D
T
L
A
L
K
P
Site 38
T401
S
T
R
H
I
T
D
T
L
A
L
K
P
M
N
Site 39
S422
M
F
A
H
R
P
R
S
W
R
E
L
P
L
R
Site 40
T449
S
G
G
L
G
G
L
T
R
L
R
C
F
Q
Q
Site 41
S474
Q
L
E
A
E
I
Q
S
C
L
D
F
L
R
S
Site 42
S530
G
E
P
W
D
L
N
S
G
D
G
A
F
Y
G
Site 43
Y571
P
L
R
F
D
L
Q
Y
K
G
Q
A
G
A
L
Site 44
Y628
V
G
S
E
Q
E
E
Y
A
K
E
A
Q
Q
S
Site 45
S635
Y
A
K
E
A
Q
Q
S
L
R
A
A
G
L
V
Site 46
S649
V
S
D
L
D
A
D
S
G
L
T
L
S
R
R
Site 47
T652
L
D
A
D
S
G
L
T
L
S
R
R
I
R
R
Site 48
S654
A
D
S
G
L
T
L
S
R
R
I
R
R
A
Q
Site 49
Y665
R
R
A
Q
L
A
H
Y
N
F
Q
F
V
V
G
Site 50
S677
V
V
G
Q
K
E
Q
S
K
R
T
V
N
I
R
Site 51
T709
R
L
V
E
L
Q
N
T
R
V
P
N
A
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation