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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRR14
Full Name:
Proline-rich protein 14
Alias:
Type:
Mass (Da):
64328
Number AA:
585
UniProt ID:
Q9BWN1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
D
L
P
G
D
S
S
P
P
G
Q
P
R
Site 2
S8
M
D
L
P
G
D
S
S
P
P
G
Q
P
R
L
Site 3
T21
R
L
C
R
Q
P
L
T
R
A
L
W
G
A
R
Site 4
S29
R
A
L
W
G
A
R
S
P
K
R
P
R
L
Q
Site 5
S42
L
Q
L
P
G
A
P
S
P
L
E
K
A
S
R
Site 6
S70
H
M
V
P
V
V
P
S
K
Q
T
S
I
P
Q
Site 7
S74
V
V
P
S
K
Q
T
S
I
P
Q
H
H
S
Y
Site 8
Y81
S
I
P
Q
H
H
S
Y
H
Q
D
P
V
H
R
Site 9
S93
V
H
R
Q
P
P
A
S
P
P
R
Q
A
G
W
Site 10
S101
P
P
R
Q
A
G
W
S
S
Q
A
R
P
P
D
Site 11
S102
P
R
Q
A
G
W
S
S
Q
A
R
P
P
D
P
Site 12
S118
C
L
C
R
E
P
L
S
R
I
H
R
T
S
S
Site 13
S124
L
S
R
I
H
R
T
S
S
T
L
R
R
R
S
Site 14
S125
S
R
I
H
R
T
S
S
T
L
R
R
R
S
R
Site 15
T126
R
I
H
R
T
S
S
T
L
R
R
R
S
R
T
Site 16
S131
S
S
T
L
R
R
R
S
R
T
T
P
G
P
E
Site 17
T133
T
L
R
R
R
S
R
T
T
P
G
P
E
E
G
Site 18
T134
L
R
R
R
S
R
T
T
P
G
P
E
E
G
P
Site 19
S142
P
G
P
E
E
G
P
S
Q
K
V
D
R
A
P
Site 20
S162
V
M
L
E
D
I
A
S
P
R
P
P
A
E
G
Site 21
T194
M
R
I
V
R
Q
P
T
P
P
P
G
D
L
E
Site 22
S207
L
E
P
P
F
Q
P
S
A
L
P
A
D
P
L
Site 23
S216
L
P
A
D
P
L
E
S
P
P
T
A
P
D
P
Site 24
T219
D
P
L
E
S
P
P
T
A
P
D
P
A
L
E
Site 25
S229
D
P
A
L
E
L
P
S
T
P
P
P
S
S
L
Site 26
T230
P
A
L
E
L
P
S
T
P
P
P
S
S
L
L
Site 27
S234
L
P
S
T
P
P
P
S
S
L
L
R
P
R
L
Site 28
S235
P
S
T
P
P
P
S
S
L
L
R
P
R
L
S
Site 29
S252
G
L
A
P
L
F
R
S
V
R
S
K
L
E
S
Site 30
S255
P
L
F
R
S
V
R
S
K
L
E
S
F
A
D
Site 31
T266
S
F
A
D
I
F
L
T
P
N
K
T
P
Q
P
Site 32
T270
I
F
L
T
P
N
K
T
P
Q
P
P
P
P
S
Site 33
S277
T
P
Q
P
P
P
P
S
P
P
M
K
L
E
L
Site 34
S289
L
E
L
K
I
A
I
S
E
A
E
Q
S
G
A
Site 35
S294
A
I
S
E
A
E
Q
S
G
A
A
E
G
T
A
Site 36
T300
Q
S
G
A
A
E
G
T
A
S
V
S
P
R
P
Site 37
S302
G
A
A
E
G
T
A
S
V
S
P
R
P
P
I
Site 38
S304
A
E
G
T
A
S
V
S
P
R
P
P
I
R
Q
Site 39
T319
W
R
T
Q
D
H
N
T
P
A
L
L
P
K
P
Site 40
S327
P
A
L
L
P
K
P
S
L
G
R
S
Y
S
C
Site 41
S331
P
K
P
S
L
G
R
S
Y
S
C
P
D
L
G
Site 42
Y332
K
P
S
L
G
R
S
Y
S
C
P
D
L
G
P
Site 43
S333
P
S
L
G
R
S
Y
S
C
P
D
L
G
P
P
Site 44
T344
L
G
P
P
G
P
G
T
C
T
W
P
P
A
P
Site 45
T346
P
P
G
P
G
T
C
T
W
P
P
A
P
P
Q
Site 46
S355
P
P
A
P
P
Q
P
S
R
P
R
P
R
R
H
Site 47
T363
R
P
R
P
R
R
H
T
V
G
G
G
E
M
A
Site 48
S395
G
G
V
G
A
S
P
S
L
T
T
S
C
S
S
Site 49
T398
G
A
S
P
S
L
T
T
S
C
S
S
T
A
S
Site 50
S399
A
S
P
S
L
T
T
S
C
S
S
T
A
S
T
Site 51
S401
P
S
L
T
T
S
C
S
S
T
A
S
T
S
F
Site 52
S402
S
L
T
T
S
C
S
S
T
A
S
T
S
F
S
Site 53
T403
L
T
T
S
C
S
S
T
A
S
T
S
F
S
E
Site 54
S405
T
S
C
S
S
T
A
S
T
S
F
S
E
P
A
Site 55
T406
S
C
S
S
T
A
S
T
S
F
S
E
P
A
E
Site 56
S407
C
S
S
T
A
S
T
S
F
S
E
P
A
E
P
Site 57
S409
S
T
A
S
T
S
F
S
E
P
A
E
P
R
L
Site 58
S418
P
A
E
P
R
L
G
S
T
K
G
K
E
P
R
Site 59
S427
K
G
K
E
P
R
A
S
K
D
Q
V
L
S
E
Site 60
S433
A
S
K
D
Q
V
L
S
E
P
E
T
K
T
M
Site 61
T437
Q
V
L
S
E
P
E
T
K
T
M
G
K
V
S
Site 62
T439
L
S
E
P
E
T
K
T
M
G
K
V
S
R
F
Site 63
S444
T
K
T
M
G
K
V
S
R
F
R
I
R
R
T
Site 64
T451
S
R
F
R
I
R
R
T
P
A
R
P
Q
L
N
Site 65
T460
A
R
P
Q
L
N
L
T
P
M
G
L
P
R
P
Site 66
S476
R
L
N
K
K
E
F
S
L
E
E
I
Y
T
N
Site 67
Y481
E
F
S
L
E
E
I
Y
T
N
K
N
Y
Q
S
Site 68
T482
F
S
L
E
E
I
Y
T
N
K
N
Y
Q
S
P
Site 69
Y486
E
I
Y
T
N
K
N
Y
Q
S
P
T
T
R
R
Site 70
S488
Y
T
N
K
N
Y
Q
S
P
T
T
R
R
T
F
Site 71
T490
N
K
N
Y
Q
S
P
T
T
R
R
T
F
E
T
Site 72
T494
Q
S
P
T
T
R
R
T
F
E
T
I
F
E
E
Site 73
T497
T
T
R
R
T
F
E
T
I
F
E
E
P
R
E
Site 74
T508
E
P
R
E
R
N
G
T
L
I
F
T
S
S
R
Site 75
T512
R
N
G
T
L
I
F
T
S
S
R
K
L
R
R
Site 76
S513
N
G
T
L
I
F
T
S
S
R
K
L
R
R
A
Site 77
S514
G
T
L
I
F
T
S
S
R
K
L
R
R
A
V
Site 78
S526
R
A
V
E
F
R
D
S
S
L
P
R
S
R
R
Site 79
S527
A
V
E
F
R
D
S
S
L
P
R
S
R
R
P
Site 80
S531
R
D
S
S
L
P
R
S
R
R
P
S
R
G
V
Site 81
S535
L
P
R
S
R
R
P
S
R
G
V
R
A
A
G
Site 82
T545
V
R
A
A
G
G
R
T
V
P
P
N
V
A
P
Site 83
T576
A
L
L
L
E
E
E
T
V
D
R
E
Q
P
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation