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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAIM2
Full Name:
Fas apoptotic inhibitory molecule 2
Alias:
Fas apoptotic inhibitory 2; KIAA0950; LFG; Lifeguard; NMP35; Protein lifeguard; TMBIM2; Transmembrane BAX inhibitor motif containing 2; Transmembrane BAX inhibitor motif-containing 2; Transmembrane BAX inhibitor motif-containing protein 2
Type:
Apoptosis
Mass (Da):
35091
Number AA:
316
UniProt ID:
Q9BWQ8
International Prot ID:
IPI00017569
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0016021
GO:0045211
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006916
GO:0006915
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
T
Q
G
K
L
S
V
A
N
K
A
P
G
Site 2
S33
K
E
A
P
A
V
P
S
A
P
P
S
Y
E
E
Site 3
S37
A
V
P
S
A
P
P
S
Y
E
E
A
T
S
G
Site 4
Y38
V
P
S
A
P
P
S
Y
E
E
A
T
S
G
E
Site 5
S43
P
S
Y
E
E
A
T
S
G
E
G
M
K
A
G
Site 6
S64
T
A
V
P
L
H
P
S
W
A
Y
V
D
P
S
Site 7
Y67
P
L
H
P
S
W
A
Y
V
D
P
S
S
S
S
Site 8
S71
S
W
A
Y
V
D
P
S
S
S
S
S
Y
D
N
Site 9
S72
W
A
Y
V
D
P
S
S
S
S
S
Y
D
N
G
Site 10
S73
A
Y
V
D
P
S
S
S
S
S
Y
D
N
G
F
Site 11
S75
V
D
P
S
S
S
S
S
Y
D
N
G
F
P
T
Site 12
Y76
D
P
S
S
S
S
S
Y
D
N
G
F
P
T
G
Site 13
T82
S
Y
D
N
G
F
P
T
G
D
H
E
L
F
T
Site 14
T90
G
D
H
E
L
F
T
T
F
S
W
D
D
Q
K
Site 15
S92
H
E
L
F
T
T
F
S
W
D
D
Q
K
V
R
Site 16
Y133
F
C
D
P
V
K
D
Y
V
Q
A
N
P
G
W
Site 17
Y141
V
Q
A
N
P
G
W
Y
W
A
S
Y
A
V
F
Site 18
S187
A
Y
L
T
G
M
L
S
S
Y
Y
N
T
T
S
Site 19
S188
Y
L
T
G
M
L
S
S
Y
Y
N
T
T
S
V
Site 20
S283
L
M
G
N
R
R
H
S
L
S
P
E
E
Y
I
Site 21
S285
G
N
R
R
H
S
L
S
P
E
E
Y
I
F
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation