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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC4A1AP
Full Name:
Kanadaptin
Alias:
Adaptor protein kanadaptin; HLC3; Kidney anion exchanger adapter protein; Lung cancer oncogene 3; NADAP; Solute carrier family 4 (anion exchanger) member 1, adaptor protein
Type:
Adapter/scaffold protein
Mass (Da):
88814
Number AA:
796
UniProt ID:
Q9BWU0
International Prot ID:
IPI00783523
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003725
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
P
G
R
E
G
A
T
S
P
S
P
P
T
D
A
Site 2
S18
R
E
G
A
T
S
P
S
P
P
T
D
A
T
G
Site 3
T21
A
T
S
P
S
P
P
T
D
A
T
G
S
L
G
Site 4
T24
P
S
P
P
T
D
A
T
G
S
L
G
E
W
D
Site 5
T38
D
V
D
R
N
V
K
T
E
G
W
V
S
K
E
Site 6
S43
V
K
T
E
G
W
V
S
K
E
R
I
S
K
L
Site 7
S48
W
V
S
K
E
R
I
S
K
L
H
R
L
R
M
Site 8
T64
D
I
L
S
Q
S
E
T
L
A
S
Q
D
L
S
Site 9
S67
S
Q
S
E
T
L
A
S
Q
D
L
S
G
D
F
Site 10
S71
T
L
A
S
Q
D
L
S
G
D
F
K
K
P
A
Site 11
S82
K
K
P
A
L
P
V
S
P
A
A
R
S
K
A
Site 12
S87
P
V
S
P
A
A
R
S
K
A
P
A
S
S
S
Site 13
S92
A
R
S
K
A
P
A
S
S
S
S
N
P
E
E
Site 14
S93
R
S
K
A
P
A
S
S
S
S
N
P
E
E
V
Site 15
S94
S
K
A
P
A
S
S
S
S
N
P
E
E
V
Q
Site 16
S95
K
A
P
A
S
S
S
S
N
P
E
E
V
Q
K
Site 17
S111
G
P
T
A
L
Q
D
S
N
S
G
E
P
D
I
Site 18
S113
T
A
L
Q
D
S
N
S
G
E
P
D
I
P
P
Site 19
S130
P
D
C
G
D
F
R
S
L
Q
E
E
Q
S
R
Site 20
S136
R
S
L
Q
E
E
Q
S
R
P
P
T
A
V
S
Site 21
T140
E
E
Q
S
R
P
P
T
A
V
S
S
P
G
G
Site 22
S143
S
R
P
P
T
A
V
S
S
P
G
G
P
A
R
Site 23
S144
R
P
P
T
A
V
S
S
P
G
G
P
A
R
A
Site 24
Y154
G
P
A
R
A
P
P
Y
Q
E
P
P
W
G
G
Site 25
T164
P
P
W
G
G
P
A
T
A
P
Y
S
L
E
T
Site 26
Y167
G
G
P
A
T
A
P
Y
S
L
E
T
L
K
G
Site 27
S168
G
P
A
T
A
P
Y
S
L
E
T
L
K
G
G
Site 28
T180
K
G
G
T
I
L
G
T
R
S
L
K
G
T
S
Site 29
S182
G
T
I
L
G
T
R
S
L
K
G
T
S
Y
C
Site 30
T186
G
T
R
S
L
K
G
T
S
Y
C
L
F
G
R
Site 31
S187
T
R
S
L
K
G
T
S
Y
C
L
F
G
R
L
Site 32
Y188
R
S
L
K
G
T
S
Y
C
L
F
G
R
L
S
Site 33
S205
D
V
C
L
E
H
P
S
V
S
R
Y
H
A
V
Site 34
Y209
E
H
P
S
V
S
R
Y
H
A
V
L
Q
H
R
Site 35
S218
A
V
L
Q
H
R
A
S
G
P
D
G
E
C
D
Site 36
S226
G
P
D
G
E
C
D
S
N
G
P
G
F
Y
L
Site 37
Y232
D
S
N
G
P
G
F
Y
L
Y
D
L
G
S
T
Site 38
Y234
N
G
P
G
F
Y
L
Y
D
L
G
S
T
H
G
Site 39
T242
D
L
G
S
T
H
G
T
F
L
N
K
T
R
I
Site 40
T247
H
G
T
F
L
N
K
T
R
I
P
P
R
T
Y
Site 41
T253
K
T
R
I
P
P
R
T
Y
C
R
V
H
V
G
Site 42
Y254
T
R
I
P
P
R
T
Y
C
R
V
H
V
G
H
Site 43
T288
R
E
A
E
S
E
L
T
V
T
Q
L
K
E
L
Site 44
T290
A
E
S
E
L
T
V
T
Q
L
K
E
L
R
K
Site 45
S312
K
K
M
L
G
E
D
S
D
E
E
E
E
M
D
Site 46
T320
D
E
E
E
E
M
D
T
S
E
R
K
I
N
A
Site 47
S321
E
E
E
E
M
D
T
S
E
R
K
I
N
A
G
Site 48
S329
E
R
K
I
N
A
G
S
Q
D
D
E
M
G
C
Site 49
Y387
R
E
G
E
E
L
E
Y
E
F
D
E
Q
G
H
Site 50
S408
V
R
L
P
V
D
D
S
T
G
K
Q
L
V
A
Site 51
T409
R
L
P
V
D
D
S
T
G
K
Q
L
V
A
E
Site 52
S420
L
V
A
E
A
I
H
S
G
K
K
K
E
A
M
Site 53
T440
E
A
C
R
I
L
D
T
L
G
L
L
R
Q
E
Site 54
S450
L
L
R
Q
E
A
V
S
R
K
R
K
A
K
N
Site 55
Y464
N
W
E
D
E
D
F
Y
D
S
D
D
D
T
F
Site 56
S466
E
D
E
D
F
Y
D
S
D
D
D
T
F
L
D
Site 57
T470
F
Y
D
S
D
D
D
T
F
L
D
R
T
G
L
Site 58
T498
K
I
D
E
K
P
E
T
F
E
S
L
V
A
K
Site 59
S501
E
K
P
E
T
F
E
S
L
V
A
K
L
N
D
Site 60
S514
N
D
A
E
R
E
L
S
E
I
S
E
R
L
K
Site 61
S523
I
S
E
R
L
K
A
S
S
Q
V
L
S
E
S
Site 62
S524
S
E
R
L
K
A
S
S
Q
V
L
S
E
S
P
Site 63
S528
K
A
S
S
Q
V
L
S
E
S
P
S
Q
D
S
Site 64
S530
S
S
Q
V
L
S
E
S
P
S
Q
D
S
L
D
Site 65
S532
Q
V
L
S
E
S
P
S
Q
D
S
L
D
A
F
Site 66
S535
S
E
S
P
S
Q
D
S
L
D
A
F
M
S
E
Site 67
S541
D
S
L
D
A
F
M
S
E
M
K
S
G
S
T
Site 68
S545
A
F
M
S
E
M
K
S
G
S
T
L
D
G
V
Site 69
S547
M
S
E
M
K
S
G
S
T
L
D
G
V
S
R
Site 70
T548
S
E
M
K
S
G
S
T
L
D
G
V
S
R
K
Site 71
S553
G
S
T
L
D
G
V
S
R
K
K
L
H
L
R
Site 72
T561
R
K
K
L
H
L
R
T
F
E
L
R
K
E
Q
Site 73
T589
E
I
P
E
L
K
K
T
E
T
Q
T
T
G
A
Site 74
S615
F
G
A
M
K
G
G
S
K
F
K
L
K
T
G
Site 75
T621
G
S
K
F
K
L
K
T
G
T
V
G
K
L
P
Site 76
T623
K
F
K
L
K
T
G
T
V
G
K
L
P
P
K
Site 77
T637
K
R
P
E
L
P
P
T
L
M
R
M
K
D
E
Site 78
S673
K
K
K
L
E
D
G
S
L
S
R
P
Q
P
E
Site 79
S675
K
L
E
D
G
S
L
S
R
P
Q
P
E
I
E
Site 80
T694
V
Q
E
M
R
P
P
T
D
L
T
H
F
K
E
Site 81
T697
M
R
P
P
T
D
L
T
H
F
K
E
T
Q
T
Site 82
T702
D
L
T
H
F
K
E
T
Q
T
H
E
N
M
S
Site 83
T704
T
H
F
K
E
T
Q
T
H
E
N
M
S
Q
L
Site 84
S709
T
Q
T
H
E
N
M
S
Q
L
S
E
E
E
Q
Site 85
S712
H
E
N
M
S
Q
L
S
E
E
E
Q
N
K
D
Site 86
Y720
E
E
E
Q
N
K
D
Y
Q
D
C
S
K
T
T
Site 87
S724
N
K
D
Y
Q
D
C
S
K
T
T
S
L
C
A
Site 88
S728
Q
D
C
S
K
T
T
S
L
C
A
G
P
S
A
Site 89
S734
T
S
L
C
A
G
P
S
A
S
K
N
E
Y
E
Site 90
Y740
P
S
A
S
K
N
E
Y
E
K
S
R
G
E
L
Site 91
S743
S
K
N
E
Y
E
K
S
R
G
E
L
K
K
K
Site 92
T752
G
E
L
K
K
K
K
T
P
G
P
G
K
L
P
Site 93
T761
G
P
G
K
L
P
P
T
L
S
S
K
Y
P
E
Site 94
S763
G
K
L
P
P
T
L
S
S
K
Y
P
E
D
D
Site 95
Y766
P
P
T
L
S
S
K
Y
P
E
D
D
P
D
Y
Site 96
Y773
Y
P
E
D
D
P
D
Y
C
V
W
V
P
P
E
Site 97
S783
W
V
P
P
E
G
Q
S
G
D
G
R
T
H
L
Site 98
Y794
R
T
H
L
N
D
K
Y
G
Y
_
_
_
_
_
Site 99
Y796
H
L
N
D
K
Y
G
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation