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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OSBPL11
Full Name:
Oxysterol-binding protein-related protein 11
Alias:
FLJ13012; FLJ13164; ORP11; ORP-11; OSB11; OSBP-related protein 11; Oxysterol binding protein-like 11; Oxysterol binding protein-related protein 11; Oxysterol-binding protein
Type:
Lipid binding protein
Mass (Da):
83643
Number AA:
747
UniProt ID:
Q9BXB4
International Prot ID:
IPI00032970
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006869
GO:0008202
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
Q
G
G
E
P
V
S
T
M
K
V
S
E
S
Site 2
T9
Q
G
G
E
P
V
S
T
M
K
V
S
E
S
E
Site 3
S13
P
V
S
T
M
K
V
S
E
S
E
G
K
L
E
Site 4
S15
S
T
M
K
V
S
E
S
E
G
K
L
E
G
Q
Site 5
T24
G
K
L
E
G
Q
A
T
A
V
T
P
N
K
N
Site 6
T27
E
G
Q
A
T
A
V
T
P
N
K
N
S
S
C
Site 7
S32
A
V
T
P
N
K
N
S
S
C
G
G
G
I
S
Site 8
S33
V
T
P
N
K
N
S
S
C
G
G
G
I
S
S
Site 9
S39
S
S
C
G
G
G
I
S
S
S
S
S
S
R
G
Site 10
S40
S
C
G
G
G
I
S
S
S
S
S
S
R
G
G
Site 11
S41
C
G
G
G
I
S
S
S
S
S
S
R
G
G
S
Site 12
S42
G
G
G
I
S
S
S
S
S
S
R
G
G
S
A
Site 13
S43
G
G
I
S
S
S
S
S
S
R
G
G
S
A
K
Site 14
S44
G
I
S
S
S
S
S
S
R
G
G
S
A
K
G
Site 15
S48
S
S
S
S
R
G
G
S
A
K
G
W
Q
Y
S
Site 16
Y62
S
D
H
M
E
N
V
Y
G
Y
L
M
K
Y
T
Site 17
Y64
H
M
E
N
V
Y
G
Y
L
M
K
Y
T
N
L
Site 18
Y91
N
E
A
G
L
L
E
Y
F
V
N
E
Q
S
R
Site 19
T105
R
N
Q
K
P
R
G
T
L
Q
L
A
G
A
V
Site 20
S114
Q
L
A
G
A
V
I
S
P
S
D
E
D
S
H
Site 21
S116
A
G
A
V
I
S
P
S
D
E
D
S
H
T
F
Site 22
S120
I
S
P
S
D
E
D
S
H
T
F
T
V
N
A
Site 23
T122
P
S
D
E
D
S
H
T
F
T
V
N
A
A
S
Site 24
T124
D
E
D
S
H
T
F
T
V
N
A
A
S
G
E
Site 25
T138
E
Q
Y
K
L
R
A
T
D
A
K
E
R
Q
H
Site 26
T154
V
S
R
L
Q
I
C
T
Q
H
H
T
E
A
I
Site 27
S170
K
N
N
P
P
L
K
S
R
S
F
S
L
A
S
Site 28
S172
N
P
P
L
K
S
R
S
F
S
L
A
S
S
S
Site 29
S174
P
L
K
S
R
S
F
S
L
A
S
S
S
N
S
Site 30
S177
S
R
S
F
S
L
A
S
S
S
N
S
P
I
S
Site 31
S178
R
S
F
S
L
A
S
S
S
N
S
P
I
S
Q
Site 32
S179
S
F
S
L
A
S
S
S
N
S
P
I
S
Q
R
Site 33
S181
S
L
A
S
S
S
N
S
P
I
S
Q
R
R
P
Site 34
S184
S
S
S
N
S
P
I
S
Q
R
R
P
S
Q
N
Site 35
S189
P
I
S
Q
R
R
P
S
Q
N
A
I
S
F
F
Site 36
S194
R
P
S
Q
N
A
I
S
F
F
N
V
G
H
S
Site 37
S201
S
F
F
N
V
G
H
S
K
L
Q
S
L
S
K
Site 38
S205
V
G
H
S
K
L
Q
S
L
S
K
R
T
N
L
Site 39
S207
H
S
K
L
Q
S
L
S
K
R
T
N
L
P
P
Site 40
T243
R
R
I
E
C
L
P
T
S
G
H
L
S
S
L
Site 41
S244
R
I
E
C
L
P
T
S
G
H
L
S
S
L
D
Site 42
S248
L
P
T
S
G
H
L
S
S
L
D
Q
D
L
L
Site 43
S249
P
T
S
G
H
L
S
S
L
D
Q
D
L
L
M
Site 44
S286
H
A
S
H
Q
K
G
S
L
P
S
G
T
T
I
Site 45
S301
E
W
L
E
P
K
I
S
L
S
N
H
Y
K
N
Site 46
S303
L
E
P
K
I
S
L
S
N
H
Y
K
N
G
A
Site 47
T352
A
D
D
E
I
E
D
T
C
D
H
K
E
D
D
Site 48
Y402
K
R
S
L
L
E
M
Y
A
D
F
M
S
H
P
Site 49
Y431
R
M
I
R
F
V
E
Y
Y
L
T
S
F
H
E
Site 50
Y432
M
I
R
F
V
E
Y
Y
L
T
S
F
H
E
G
Site 51
T434
R
F
V
E
Y
Y
L
T
S
F
H
E
G
R
K
Site 52
S435
F
V
E
Y
Y
L
T
S
F
H
E
G
R
K
G
Site 53
S466
C
S
W
K
M
P
K
S
E
V
A
S
S
V
F
Site 54
S470
M
P
K
S
E
V
A
S
S
V
F
S
S
S
S
Site 55
S471
P
K
S
E
V
A
S
S
V
F
S
S
S
S
T
Site 56
S474
E
V
A
S
S
V
F
S
S
S
S
T
Q
G
V
Site 57
S476
A
S
S
V
F
S
S
S
S
T
Q
G
V
T
N
Site 58
S477
S
S
V
F
S
S
S
S
T
Q
G
V
T
N
H
Site 59
T478
S
V
F
S
S
S
S
T
Q
G
V
T
N
H
A
Site 60
S488
V
T
N
H
A
P
L
S
G
E
S
L
T
Q
V
Site 61
S491
H
A
P
L
S
G
E
S
L
T
Q
V
G
S
D
Site 62
T493
P
L
S
G
E
S
L
T
Q
V
G
S
D
C
Y
Site 63
S497
E
S
L
T
Q
V
G
S
D
C
Y
T
V
R
F
Site 64
Y500
T
Q
V
G
S
D
C
Y
T
V
R
F
V
A
E
Site 65
T501
Q
V
G
S
D
C
Y
T
V
R
F
V
A
E
Q
Site 66
S510
R
F
V
A
E
Q
V
S
H
H
P
P
V
S
G
Site 67
Y563
L
L
E
H
G
E
E
Y
T
F
S
L
P
C
A
Site 68
T564
L
E
H
G
E
E
Y
T
F
S
L
P
C
A
Y
Site 69
S566
H
G
E
E
Y
T
F
S
L
P
C
A
Y
A
R
Site 70
S599
A
K
T
G
Y
S
A
S
I
T
F
H
T
K
P
Site 71
T601
T
G
Y
S
A
S
I
T
F
H
T
K
P
F
Y
Site 72
Y608
T
F
H
T
K
P
F
Y
G
G
K
L
H
R
V
Site 73
T616
G
G
K
L
H
R
V
T
A
E
V
K
H
N
I
Site 74
T626
V
K
H
N
I
T
N
T
V
V
C
R
V
Q
G
Site 75
S637
R
V
Q
G
E
W
N
S
V
L
E
F
T
Y
S
Site 76
S644
S
V
L
E
F
T
Y
S
N
G
E
T
K
Y
V
Site 77
T648
F
T
Y
S
N
G
E
T
K
Y
V
D
L
T
K
Site 78
Y650
Y
S
N
G
E
T
K
Y
V
D
L
T
K
L
A
Site 79
T654
E
T
K
Y
V
D
L
T
K
L
A
V
T
K
K
Site 80
S674
E
K
Q
D
P
F
E
S
R
R
L
W
K
N
V
Site 81
T682
R
R
L
W
K
N
V
T
D
S
L
R
E
S
E
Site 82
S684
L
W
K
N
V
T
D
S
L
R
E
S
E
I
D
Site 83
S688
V
T
D
S
L
R
E
S
E
I
D
K
A
T
E
Site 84
T699
K
A
T
E
H
K
H
T
L
E
E
R
Q
R
T
Site 85
T706
T
L
E
E
R
Q
R
T
E
E
R
H
R
T
E
Site 86
T712
R
T
E
E
R
H
R
T
E
T
G
T
P
W
K
Site 87
T714
E
E
R
H
R
T
E
T
G
T
P
W
K
T
K
Site 88
T716
R
H
R
T
E
T
G
T
P
W
K
T
K
Y
F
Site 89
Y722
G
T
P
W
K
T
K
Y
F
I
K
E
G
D
G
Site 90
Y732
K
E
G
D
G
W
V
Y
H
K
P
L
W
K
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation