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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NT5C1A
Full Name:
Cytosolic 5'-nucleotidase 1A
Alias:
5NT1A; CN1A; CN-I; CN-IA; Cytosolic ''nucleotidase 1A; Cytosolic ''nucleotidase IA; EC 3.1.3.5; MGC119199; MGC119201; Nucleotidase, cytosolic IA
Type:
Enzyme - Nucleotidase
Mass (Da):
41021
Number AA:
368
UniProt ID:
Q9BXI3
International Prot ID:
IPI00000146
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0008253
GO:0000287
GO:0000166
PhosphoSite+
KinaseNET
Biological Process:
GO:0009116
GO:0009117
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y34
W
E
E
A
K
I
F
Y
D
N
L
A
P
K
K
Site 2
S45
A
P
K
K
K
P
K
S
P
K
P
Q
N
A
V
Site 3
T53
P
K
P
Q
N
A
V
T
I
A
V
S
S
R
A
Site 4
Y71
M
D
E
E
Q
Q
I
Y
T
E
Q
G
V
E
E
Site 5
Y79
T
E
Q
G
V
E
E
Y
V
R
Y
Q
L
E
H
Site 6
Y82
G
V
E
E
Y
V
R
Y
Q
L
E
H
E
N
E
Site 7
S92
E
H
E
N
E
P
F
S
P
G
P
A
F
P
F
Site 8
Y114
N
R
R
L
R
E
L
Y
P
D
S
E
D
V
F
Site 9
S117
L
R
E
L
Y
P
D
S
E
D
V
F
D
I
V
Site 10
Y162
G
G
N
S
P
I
C
Y
L
K
A
Y
H
T
N
Site 11
T168
C
Y
L
K
A
Y
H
T
N
L
Y
L
S
A
D
Site 12
Y171
K
A
Y
H
T
N
L
Y
L
S
A
D
A
E
K
Site 13
S173
Y
H
T
N
L
Y
L
S
A
D
A
E
K
V
R
Site 14
S202
P
S
R
D
V
V
V
S
Q
S
Q
L
R
V
A
Site 15
S204
R
D
V
V
V
S
Q
S
Q
L
R
V
A
F
D
Site 16
S218
D
G
D
A
V
L
F
S
D
E
S
E
R
I
V
Site 17
S221
A
V
L
F
S
D
E
S
E
R
I
V
K
A
H
Site 18
Y265
G
R
L
Q
K
K
F
Y
S
K
G
L
R
L
E
Site 19
S266
R
L
Q
K
K
F
Y
S
K
G
L
R
L
E
C
Site 20
Y278
L
E
C
P
I
R
T
Y
L
V
T
A
R
S
A
Site 21
T281
P
I
R
T
Y
L
V
T
A
R
S
A
A
S
S
Site 22
S284
T
Y
L
V
T
A
R
S
A
A
S
S
G
A
R
Site 23
S288
T
A
R
S
A
A
S
S
G
A
R
A
L
K
T
Site 24
T295
S
G
A
R
A
L
K
T
L
R
S
W
G
L
E
Site 25
S298
R
A
L
K
T
L
R
S
W
G
L
E
T
D
E
Site 26
T354
V
P
Y
G
V
A
Q
T
P
R
R
T
A
P
A
Site 27
T358
V
A
Q
T
P
R
R
T
A
P
A
K
Q
A
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation