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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HEMGN
Full Name:
Hemogen
Alias:
EDAG; EDAG-1; Erythroid differentiation-associated gene; Hemopoietic gene protein; NDR; Negative differentiation regulator protein
Type:
Apoptosis
Mass (Da):
55341
Number AA:
484
UniProt ID:
Q9BXL5
International Prot ID:
IPI00464963
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0007275
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
S
H
L
K
H
H
Q
T
P
D
P
H
Q
E
E
Site 2
S25
P
H
Q
E
E
N
H
S
P
E
V
I
G
T
W
Site 3
T31
H
S
P
E
V
I
G
T
W
S
L
R
N
R
E
Site 4
S33
P
E
V
I
G
T
W
S
L
R
N
R
E
L
L
Site 5
S53
E
V
H
E
K
E
T
S
Q
W
L
F
G
E
Q
Site 6
T68
K
K
R
K
Q
Q
R
T
G
K
G
N
R
R
G
Site 7
T108
L
A
P
I
E
K
K
T
E
P
P
G
S
I
T
Site 8
S113
K
K
T
E
P
P
G
S
I
T
K
V
F
P
S
Site 9
S123
K
V
F
P
S
V
A
S
P
Q
K
V
V
P
E
Site 10
S134
V
V
P
E
E
H
F
S
E
I
C
Q
E
S
N
Site 11
Y143
I
C
Q
E
S
N
I
Y
Q
E
N
F
S
E
Y
Site 12
S160
I
A
V
Q
N
H
S
S
E
T
C
Q
H
V
S
Site 13
S167
S
E
T
C
Q
H
V
S
E
P
E
D
L
S
P
Site 14
S173
V
S
E
P
E
D
L
S
P
K
M
Y
Q
E
I
Site 15
Y177
E
D
L
S
P
K
M
Y
Q
E
I
S
V
L
Q
Site 16
S181
P
K
M
Y
Q
E
I
S
V
L
Q
D
N
S
S
Site 17
S188
S
V
L
Q
D
N
S
S
K
I
C
Q
D
M
K
Site 18
S201
M
K
E
P
E
D
N
S
P
N
T
C
Q
V
I
Site 19
T204
P
E
D
N
S
P
N
T
C
Q
V
I
S
V
I
Site 20
S247
K
I
L
P
C
P
T
S
E
D
T
A
D
L
A
Site 21
S257
T
A
D
L
A
G
C
S
L
Q
A
Y
P
K
P
Site 22
Y261
A
G
C
S
L
Q
A
Y
P
K
P
D
V
P
K
Site 23
T274
P
K
G
Y
I
L
D
T
D
Q
N
P
A
E
P
Site 24
Y284
N
P
A
E
P
E
E
Y
N
E
T
D
Q
G
I
Site 25
T287
E
P
E
E
Y
N
E
T
D
Q
G
I
A
E
T
Site 26
S311
I
A
E
P
K
D
L
S
T
K
T
H
Q
E
S
Site 27
T314
P
K
D
L
S
T
K
T
H
Q
E
S
A
E
P
Site 28
Y323
Q
E
S
A
E
P
K
Y
L
P
H
K
T
C
N
Site 29
T328
P
K
Y
L
P
H
K
T
C
N
E
I
I
V
P
Site 30
S339
I
I
V
P
K
A
P
S
H
K
T
I
Q
E
T
Site 31
T342
P
K
A
P
S
H
K
T
I
Q
E
T
P
H
S
Site 32
T346
S
H
K
T
I
Q
E
T
P
H
S
E
D
Y
S
Site 33
S349
T
I
Q
E
T
P
H
S
E
D
Y
S
I
E
I
Site 34
Y352
E
T
P
H
S
E
D
Y
S
I
E
I
N
Q
E
Site 35
S353
T
P
H
S
E
D
Y
S
I
E
I
N
Q
E
T
Site 36
T360
S
I
E
I
N
Q
E
T
P
G
S
E
K
Y
S
Site 37
S363
I
N
Q
E
T
P
G
S
E
K
Y
S
P
E
T
Site 38
S367
T
P
G
S
E
K
Y
S
P
E
T
Y
Q
E
I
Site 39
T370
S
E
K
Y
S
P
E
T
Y
Q
E
I
P
G
L
Site 40
Y371
E
K
Y
S
P
E
T
Y
Q
E
I
P
G
L
E
Site 41
S381
I
P
G
L
E
E
Y
S
P
E
I
Y
Q
E
T
Site 42
Y385
E
E
Y
S
P
E
I
Y
Q
E
T
S
Q
L
E
Site 43
S389
P
E
I
Y
Q
E
T
S
Q
L
E
E
Y
S
P
Site 44
S395
T
S
Q
L
E
E
Y
S
P
E
I
Y
Q
E
T
Site 45
Y399
E
E
Y
S
P
E
I
Y
Q
E
T
P
G
P
E
Site 46
T402
S
P
E
I
Y
Q
E
T
P
G
P
E
D
L
S
Site 47
S409
T
P
G
P
E
D
L
S
T
E
T
Y
K
N
K
Site 48
T410
P
G
P
E
D
L
S
T
E
T
Y
K
N
K
D
Site 49
Y413
E
D
L
S
T
E
T
Y
K
N
K
D
V
P
K
Site 50
Y449
Q
E
D
A
K
D
A
Y
T
F
P
Q
E
M
K
Site 51
T450
E
D
A
K
D
A
Y
T
F
P
Q
E
M
K
E
Site 52
Y479
S
H
P
E
N
D
V
Y
S
Y
V
L
F
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation