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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRX
Full Name:
Periaxin
Alias:
CMT4F; KIAA1620; PRAX
Type:
Cell surface
Mass (Da):
155004
Number AA:
1461
UniProt ID:
Q9BXM0
International Prot ID:
IPI00024853
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0008366
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
E
A
R
S
R
S
A
E
E
L
R
R
A
Site 2
S51
V
R
E
L
R
E
D
S
P
A
A
R
S
L
S
Site 3
S56
E
D
S
P
A
A
R
S
L
S
L
Q
E
G
D
Site 4
S58
S
P
A
A
R
S
L
S
L
Q
E
G
D
Q
L
Site 5
S67
Q
E
G
D
Q
L
L
S
A
R
V
F
F
E
N
Site 6
T102
C
L
K
R
T
V
P
T
G
D
L
A
L
R
P
Site 7
T111
D
L
A
L
R
P
G
T
V
S
G
Y
E
I
K
Site 8
S113
A
L
R
P
G
T
V
S
G
Y
E
I
K
G
P
Site 9
Y115
R
P
G
T
V
S
G
Y
E
I
K
G
P
R
A
Site 10
S131
V
A
K
L
N
I
Q
S
L
S
P
V
K
K
K
Site 11
S133
K
L
N
I
Q
S
L
S
P
V
K
K
K
K
M
Site 12
S164
E
F
S
F
P
K
F
S
R
L
R
R
G
L
K
Site 13
S259
S
A
P
K
A
A
P
S
A
E
A
A
G
G
F
Site 14
T308
P
S
L
P
T
L
P
T
L
P
C
L
E
T
R
Site 15
S361
A
L
K
M
P
R
L
S
F
P
R
F
G
A
R
Site 16
S381
E
A
K
V
A
K
V
S
P
E
A
R
V
K
G
Site 17
S399
R
M
P
T
F
G
L
S
L
L
E
P
R
P
A
Site 18
S424
L
P
T
I
K
M
P
S
L
G
I
G
V
S
G
Site 19
S430
P
S
L
G
I
G
V
S
G
P
E
V
K
V
P
Site 20
T805
G
F
K
M
P
K
M
T
M
P
K
L
G
R
A
Site 21
S814
P
K
L
G
R
A
E
S
P
S
R
G
K
P
G
Site 22
S816
L
G
R
A
E
S
P
S
R
G
K
P
G
E
A
Site 23
S900
E
V
G
F
R
V
P
S
V
E
I
V
T
P
Q
Site 24
T923
G
R
L
E
M
I
E
T
K
V
K
P
S
S
K
Site 25
S928
I
E
T
K
V
K
P
S
S
K
F
S
L
P
K
Site 26
S929
E
T
K
V
K
P
S
S
K
F
S
L
P
K
F
Site 27
S932
V
K
P
S
S
K
F
S
L
P
K
F
G
L
S
Site 28
S939
S
L
P
K
F
G
L
S
G
P
K
V
A
K
A
Site 29
T955
A
E
G
A
G
R
A
T
K
L
K
V
S
K
F
Site 30
S997
D
L
S
I
P
Q
L
S
L
D
A
H
L
P
S
Site 31
S1004
S
L
D
A
H
L
P
S
G
K
V
E
V
A
G
Site 32
T1033
F
G
V
R
G
R
D
T
E
A
A
E
L
V
P
Site 33
S1065
M
P
K
L
K
M
P
S
F
G
L
A
R
G
K
Site 34
S1082
E
V
Q
G
D
R
A
S
P
G
E
K
A
E
S
Site 35
S1089
S
P
G
E
K
A
E
S
T
A
V
Q
L
K
I
Site 36
S1119
A
E
G
A
V
A
V
S
G
M
Q
L
S
G
L
Site 37
T1165
T
G
F
G
E
A
G
T
P
G
Q
Q
A
Q
S
Site 38
S1172
T
P
G
Q
Q
A
Q
S
T
V
P
S
A
E
G
Site 39
T1173
P
G
Q
Q
A
Q
S
T
V
P
S
A
E
G
T
Site 40
S1176
Q
A
Q
S
T
V
P
S
A
E
G
T
A
G
Y
Site 41
S1228
L
E
L
D
V
G
L
S
R
E
A
Q
A
G
E
Site 42
T1271
Q
P
P
G
A
E
R
T
F
C
L
S
L
P
D
Site 43
S1282
S
L
P
D
V
E
L
S
P
S
G
G
N
H
A
Site 44
S1284
P
D
V
E
L
S
P
S
G
G
N
H
A
E
Y
Site 45
Y1291
S
G
G
N
H
A
E
Y
Q
V
A
E
G
E
G
Site 46
S1328
E
E
G
E
K
A
K
S
P
K
L
R
L
P
R
Site 47
S1339
R
L
P
R
V
G
F
S
Q
S
E
M
V
T
G
Site 48
S1341
P
R
V
G
F
S
Q
S
E
M
V
T
G
E
G
Site 49
T1345
F
S
Q
S
E
M
V
T
G
E
G
S
P
S
P
Site 50
S1349
E
M
V
T
G
E
G
S
P
S
P
E
E
E
E
Site 51
S1351
V
T
G
E
G
S
P
S
P
E
E
E
E
E
E
Site 52
S1363
E
E
E
E
E
E
G
S
G
E
G
A
S
G
R
Site 53
S1368
E
G
S
G
E
G
A
S
G
R
R
G
R
V
R
Site 54
S1401
E
G
D
A
A
P
K
S
P
V
R
E
K
S
P
Site 55
S1407
K
S
P
V
R
E
K
S
P
K
F
R
F
P
R
Site 56
S1416
K
F
R
F
P
R
V
S
L
S
P
K
A
R
S
Site 57
S1418
R
F
P
R
V
S
L
S
P
K
A
R
S
G
S
Site 58
S1423
S
L
S
P
K
A
R
S
G
S
G
D
Q
E
E
Site 59
S1425
S
P
K
A
R
S
G
S
G
D
Q
E
E
G
G
Site 60
S1439
G
L
R
V
R
L
P
S
V
G
F
S
E
T
G
Site 61
S1443
R
L
P
S
V
G
F
S
E
T
G
A
P
G
P
Site 62
T1445
P
S
V
G
F
S
E
T
G
A
P
G
P
A
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation