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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CECR6
Full Name:
Cat eye syndrome critical region protein 6
Alias:
cat eye syndrome chromosome region, candidate 6; cat eye syndrome critical region 6
Type:
Mass (Da):
58406
Number AA:
578
UniProt ID:
Q9BXQ6
International Prot ID:
IPI00010832
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
P
A
L
G
H
P
R
S
V
S
S
A
S
G
S
Site 2
S12
L
G
H
P
R
S
V
S
S
A
S
G
S
F
P
Site 3
S13
G
H
P
R
S
V
S
S
A
S
G
S
F
P
P
Site 4
S15
P
R
S
V
S
S
A
S
G
S
F
P
P
P
P
Site 5
S17
S
V
S
S
A
S
G
S
F
P
P
P
P
A
A
Site 6
S36
P
L
F
L
R
G
G
S
F
R
G
R
R
G
S
Site 7
S43
S
F
R
G
R
R
G
S
G
D
S
S
T
S
T
Site 8
S46
G
R
R
G
S
G
D
S
S
T
S
T
S
T
S
Site 9
S47
R
R
G
S
G
D
S
S
T
S
T
S
T
S
R
Site 10
T48
R
G
S
G
D
S
S
T
S
T
S
T
S
R
G
Site 11
S49
G
S
G
D
S
S
T
S
T
S
T
S
R
G
G
Site 12
T50
S
G
D
S
S
T
S
T
S
T
S
R
G
G
G
Site 13
S51
G
D
S
S
T
S
T
S
T
S
R
G
G
G
G
Site 14
T52
D
S
S
T
S
T
S
T
S
R
G
G
G
G
G
Site 15
S53
S
S
T
S
T
S
T
S
R
G
G
G
G
G
R
Site 16
S67
R
R
G
G
G
G
G
S
P
S
S
S
T
G
A
Site 17
S69
G
G
G
G
G
S
P
S
S
S
T
G
A
E
R
Site 18
S70
G
G
G
G
S
P
S
S
S
T
G
A
E
R
E
Site 19
S71
G
G
G
S
P
S
S
S
T
G
A
E
R
E
D
Site 20
S82
E
R
E
D
D
D
E
S
L
S
V
S
K
P
L
Site 21
S84
E
D
D
D
E
S
L
S
V
S
K
P
L
V
P
Site 22
S86
D
D
E
S
L
S
V
S
K
P
L
V
P
N
A
Site 23
T119
A
F
S
S
S
A
A
T
S
S
S
T
S
T
P
Site 24
S120
F
S
S
S
A
A
T
S
S
S
T
S
T
P
T
Site 25
S121
S
S
S
A
A
T
S
S
S
T
S
T
P
T
S
Site 26
S122
S
S
A
A
T
S
S
S
T
S
T
P
T
S
S
Site 27
T123
S
A
A
T
S
S
S
T
S
T
P
T
S
S
C
Site 28
S124
A
A
T
S
S
S
T
S
T
P
T
S
S
C
S
Site 29
T125
A
T
S
S
S
T
S
T
P
T
S
S
C
S
M
Site 30
T127
S
S
S
T
S
T
P
T
S
S
C
S
M
T
A
Site 31
S128
S
S
T
S
T
P
T
S
S
C
S
M
T
A
A
Site 32
S129
S
T
S
T
P
T
S
S
C
S
M
T
A
A
D
Site 33
S131
S
T
P
T
S
S
C
S
M
T
A
A
D
F
G
Site 34
T133
P
T
S
S
C
S
M
T
A
A
D
F
G
G
G
Site 35
S151
G
A
V
G
G
P
G
S
R
S
A
G
G
A
G
Site 36
S153
V
G
G
P
G
S
R
S
A
G
G
A
G
G
T
Site 37
T160
S
A
G
G
A
G
G
T
G
T
G
S
G
A
S
Site 38
S167
T
G
T
G
S
G
A
S
C
C
P
C
C
C
C
Site 39
S193
R
R
R
G
C
A
P
S
P
R
C
R
W
G
Y
Site 40
Y200
S
P
R
C
R
W
G
Y
Q
A
L
S
V
V
L
Site 41
S249
A
I
F
F
A
K
N
S
R
G
R
R
G
G
A
Site 42
S258
G
R
R
G
G
A
A
S
G
A
H
N
H
H
L
Site 43
T349
E
L
R
A
P
F
G
T
T
G
F
R
L
T
M
Site 44
S460
A
A
S
W
G
Q
A
S
G
P
G
S
C
S
R
Site 45
S464
G
Q
A
S
G
P
G
S
C
S
R
L
L
R
L
Site 46
S526
W
D
R
G
N
R
A
S
P
S
R
A
R
G
G
Site 47
S528
R
G
N
R
A
S
P
S
R
A
R
G
G
Y
G
Site 48
Y534
P
S
R
A
R
G
G
Y
G
A
P
P
S
A
P
Site 49
S539
G
G
Y
G
A
P
P
S
A
P
P
P
P
P
P
Site 50
S552
P
P
P
P
Q
G
G
S
Q
L
G
H
C
I
S
Site 51
S559
S
Q
L
G
H
C
I
S
E
N
E
G
G
A
H
Site 52
T571
G
A
H
G
Y
V
N
T
L
A
V
A
S
Q
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation