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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ERVK6
Full Name:
HERV-K_7p22.1 provirus ancestral Pol protein
Alias:
HERV-K(C7) Pol protein;HERV-K(HML-2.HOM) Pol protein;HERV-K108 Pol protein
Type:
Mass (Da):
107688
Number AA:
956
UniProt ID:
Q9BXR3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
R
K
R
R
N
R
E
S
L
L
G
A
A
T
V
Site 2
T27
P
P
K
P
I
P
L
T
W
K
T
E
K
P
V
Site 3
S65
E
K
G
H
I
E
P
S
F
S
P
W
N
S
P
Site 4
S67
G
H
I
E
P
S
F
S
P
W
N
S
P
V
F
Site 5
S71
P
S
F
S
P
W
N
S
P
V
F
V
I
Q
K
Site 6
T87
S
G
K
W
R
M
L
T
D
L
R
A
V
N
A
Site 7
S108
P
L
Q
P
G
L
P
S
P
A
M
I
P
K
D
Site 8
T174
N
S
P
T
I
C
Q
T
F
V
G
R
A
L
Q
Site 9
Y191
R
E
K
F
S
D
C
Y
I
I
H
C
I
D
D
Site 10
Y213
K
D
K
L
I
D
C
Y
T
F
L
Q
A
E
V
Site 11
S235
A
S
D
K
I
Q
T
S
T
P
F
H
Y
L
G
Site 12
T236
S
D
K
I
Q
T
S
T
P
F
H
Y
L
G
M
Site 13
T261
K
I
E
I
R
K
D
T
L
K
T
L
N
D
F
Site 14
T264
I
R
K
D
T
L
K
T
L
N
D
F
Q
K
L
Site 15
T281
D
I
N
W
I
R
P
T
L
G
I
P
T
Y
A
Site 16
S294
Y
A
M
S
N
L
F
S
I
L
R
G
D
S
D
Site 17
S300
F
S
I
L
R
G
D
S
D
L
N
S
K
R
M
Site 18
S304
R
G
D
S
D
L
N
S
K
R
M
L
T
P
E
Site 19
T309
L
N
S
K
R
M
L
T
P
E
A
T
K
E
I
Site 20
S362
N
T
D
L
V
E
W
S
F
L
P
H
S
T
V
Site 21
S367
E
W
S
F
L
P
H
S
T
V
K
T
F
T
L
Site 22
T371
L
P
H
S
T
V
K
T
F
T
L
Y
L
D
Q
Site 23
Y435
V
G
I
I
D
N
H
Y
P
K
T
K
I
F
Q
Site 24
T465
E
P
L
E
N
A
L
T
V
F
T
D
G
S
S
Site 25
S471
L
T
V
F
T
D
G
S
S
N
G
K
A
A
Y
Site 26
Y478
S
S
N
G
K
A
A
Y
T
G
P
K
E
R
V
Site 27
T488
P
K
E
R
V
I
K
T
P
Y
Q
S
A
Q
R
Site 28
Y520
N
I
I
S
D
S
A
Y
V
V
Q
A
T
R
D
Site 29
S536
E
T
A
L
I
K
Y
S
M
D
D
Q
L
N
Q
Site 30
T551
L
F
N
L
L
Q
Q
T
V
R
K
R
N
F
P
Site 31
Y560
R
K
R
N
F
P
F
Y
I
T
H
I
R
A
H
Site 32
T568
I
T
H
I
R
A
H
T
N
L
P
G
P
L
T
Site 33
T575
T
N
L
P
G
P
L
T
K
A
N
E
Q
A
D
Site 34
T655
A
L
W
Q
M
D
V
T
H
V
P
S
F
G
R
Site 35
Y665
P
S
F
G
R
L
S
Y
V
H
V
T
V
D
T
Site 36
T669
R
L
S
Y
V
H
V
T
V
D
T
Y
S
H
F
Site 37
S688
C
Q
T
G
E
S
T
S
H
V
K
K
H
L
L
Site 38
T709
G
V
P
E
K
I
K
T
D
N
G
P
G
Y
C
Site 39
Y715
K
T
D
N
G
P
G
Y
C
S
K
A
F
Q
K
Site 40
Y737
S
H
T
T
G
I
P
Y
N
S
Q
G
Q
A
I
Site 41
T754
R
T
N
R
T
L
K
T
Q
L
V
K
Q
K
E
Site 42
S765
K
Q
K
E
G
G
D
S
K
E
C
T
T
P
Q
Site 43
T769
G
G
D
S
K
E
C
T
T
P
Q
M
Q
L
N
Site 44
T770
G
D
S
K
E
C
T
T
P
Q
M
Q
L
N
L
Site 45
T792
L
N
I
Y
R
N
Q
T
T
T
S
A
E
Q
H
Site 46
T794
I
Y
R
N
Q
T
T
T
S
A
E
Q
H
L
T
Site 47
T801
T
S
A
E
Q
H
L
T
G
K
K
N
S
P
H
Site 48
S806
H
L
T
G
K
K
N
S
P
H
E
G
K
L
I
Site 49
S839
G
R
G
F
A
C
V
S
P
G
E
N
Q
L
P
Site 50
Y857
P
T
R
H
L
K
F
Y
N
E
P
I
R
D
A
Site 51
S867
P
I
R
D
A
K
K
S
T
S
A
E
T
E
T
Site 52
S875
T
S
A
E
T
E
T
S
Q
S
S
T
V
D
S
Site 53
S877
A
E
T
E
T
S
Q
S
S
T
V
D
S
Q
D
Site 54
S878
E
T
E
T
S
Q
S
S
T
V
D
S
Q
D
E
Site 55
T879
T
E
T
S
Q
S
S
T
V
D
S
Q
D
E
Q
Site 56
S882
S
Q
S
S
T
V
D
S
Q
D
E
Q
N
G
D
Site 57
T893
Q
N
G
D
V
R
R
T
D
E
V
A
I
H
Q
Site 58
S917
T
K
E
A
D
A
V
S
Y
K
I
S
R
E
H
Site 59
S921
D
A
V
S
Y
K
I
S
R
E
H
K
G
D
T
Site 60
T928
S
R
E
H
K
G
D
T
N
P
R
E
Y
A
A
Site 61
Y933
G
D
T
N
P
R
E
Y
A
A
C
S
L
D
D
Site 62
S937
P
R
E
Y
A
A
C
S
L
D
D
C
I
N
G
Site 63
S947
D
C
I
N
G
G
K
S
P
Y
A
C
R
S
S
Site 64
Y949
I
N
G
G
K
S
P
Y
A
C
R
S
S
C
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation