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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CFHR5
Full Name:
Complement factor H-related protein 5
Alias:
Type:
Mass (Da):
64419
Number AA:
569
UniProt ID:
Q9BXR6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y34
K
I
H
H
G
F
L
Y
D
E
E
D
Y
N
P
Site 2
Y39
F
L
Y
D
E
E
D
Y
N
P
F
S
Q
V
P
Site 3
S43
E
E
D
Y
N
P
F
S
Q
V
P
T
G
E
V
Site 4
T47
N
P
F
S
Q
V
P
T
G
E
V
F
Y
Y
S
Site 5
Y52
V
P
T
G
E
V
F
Y
Y
S
C
E
Y
N
F
Site 6
Y53
P
T
G
E
V
F
Y
Y
S
C
E
Y
N
F
V
Site 7
Y57
V
F
Y
Y
S
C
E
Y
N
F
V
S
P
S
K
Site 8
S61
S
C
E
Y
N
F
V
S
P
S
K
S
F
W
T
Site 9
S78
T
C
T
E
E
G
W
S
P
T
P
K
C
L
R
Site 10
T80
T
E
E
G
W
S
P
T
P
K
C
L
R
M
C
Site 11
S97
P
F
V
K
N
G
H
S
E
S
S
G
L
I
H
Site 12
S100
K
N
G
H
S
E
S
S
G
L
I
H
L
E
G
Site 13
S135
S
C
V
E
R
G
W
S
T
P
P
I
C
S
F
Site 14
T136
C
V
E
R
G
W
S
T
P
P
I
C
S
F
T
Site 15
Y165
A
Q
P
K
K
E
S
Y
K
V
G
D
V
L
K
Site 16
S174
V
G
D
V
L
K
F
S
C
R
K
N
L
I
R
Site 17
S184
K
N
L
I
R
V
G
S
D
S
V
Q
C
Y
Q
Site 18
S186
L
I
R
V
G
S
D
S
V
Q
C
Y
Q
F
G
Site 19
Y190
G
S
D
S
V
Q
C
Y
Q
F
G
W
S
P
N
Site 20
T200
G
W
S
P
N
F
P
T
C
K
G
Q
V
R
S
Site 21
S207
T
C
K
G
Q
V
R
S
C
G
P
P
P
Q
L
Site 22
S215
C
G
P
P
P
Q
L
S
N
G
E
V
K
E
I
Site 23
Y235
G
H
N
E
V
V
E
Y
D
C
N
P
N
F
I
Site 24
Y277
G
Y
I
P
E
L
E
Y
G
Y
V
Q
P
S
V
Site 25
Y279
I
P
E
L
E
Y
G
Y
V
Q
P
S
V
P
P
Site 26
S283
E
Y
G
Y
V
Q
P
S
V
P
P
Y
Q
H
G
Site 27
Y287
V
Q
P
S
V
P
P
Y
Q
H
G
V
S
V
E
Site 28
Y301
E
V
N
C
R
N
E
Y
A
M
I
G
N
N
M
Site 29
S345
I
K
T
L
L
K
L
S
G
K
E
F
N
H
N
Site 30
Y357
N
H
N
S
R
I
R
Y
R
C
S
D
I
F
R
Site 31
Y365
R
C
S
D
I
F
R
Y
R
H
S
V
C
I
N
Site 32
T404
N
A
Q
N
M
T
T
T
V
N
Y
Q
D
G
E
Site 33
Y421
A
V
L
C
K
E
N
Y
L
L
P
E
A
K
E
Site 34
S438
C
K
D
G
R
W
Q
S
L
P
R
C
V
E
S
Site 35
T446
L
P
R
C
V
E
S
T
A
Y
C
G
P
P
P
Site 36
Y448
R
C
V
E
S
T
A
Y
C
G
P
P
P
S
I
Site 37
S454
A
Y
C
G
P
P
P
S
I
N
N
G
D
T
T
Site 38
T460
P
S
I
N
N
G
D
T
T
S
F
P
L
S
V
Site 39
T461
S
I
N
N
G
D
T
T
S
F
P
L
S
V
Y
Site 40
S462
I
N
N
G
D
T
T
S
F
P
L
S
V
Y
P
Site 41
S466
D
T
T
S
F
P
L
S
V
Y
P
P
G
S
T
Site 42
S472
L
S
V
Y
P
P
G
S
T
V
T
Y
R
C
Q
Site 43
T475
Y
P
P
G
S
T
V
T
Y
R
C
Q
S
F
Y
Site 44
Y476
P
P
G
S
T
V
T
Y
R
C
Q
S
F
Y
K
Site 45
S480
T
V
T
Y
R
C
Q
S
F
Y
K
L
Q
G
S
Site 46
Y482
T
Y
R
C
Q
S
F
Y
K
L
Q
G
S
V
T
Site 47
S487
S
F
Y
K
L
Q
G
S
V
T
V
T
C
R
N
Site 48
T489
Y
K
L
Q
G
S
V
T
V
T
C
R
N
K
Q
Site 49
T491
L
Q
G
S
V
T
V
T
C
R
N
K
Q
W
S
Site 50
Y530
W
R
N
D
G
K
L
Y
A
K
T
G
D
A
V
Site 51
S551
P
H
K
A
M
I
S
S
P
P
F
R
A
I
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation