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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AP1M1
Full Name:
AP-1 complex subunit mu-1
Alias:
Adaptor protein complex AP-1 mu-1; Adaptor-related protein complex 1 mu-1 subunit; Adaptor-related protein complex 1, mu 1 subunit; AP47; AP-mu chain family member mu1A; CLAPM2; Clathrin assembly protein complex 1 medium chain 1; Clathrin coat-associated protein AP47; Golgi adaptor HA1/AP1 adaptin mu-1 subunit; Mu1A-adaptin; Mu-adaptin 1
Type:
Vesicle protein
Mass (Da):
48587
Number AA:
423
UniProt ID:
Q9BXS5
International Prot ID:
IPI00032516
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005829
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0006886
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y21
K
V
L
I
C
R
N
Y
R
G
D
V
D
M
S
Site 2
S47
K
E
E
E
G
M
L
S
P
I
L
A
H
G
G
Site 3
Y66
W
I
K
H
N
N
L
Y
L
V
A
T
S
K
K
Site 4
Y94
V
V
Q
V
F
S
E
Y
F
K
E
L
E
E
E
Site 5
S102
F
K
E
L
E
E
E
S
I
R
D
N
F
V
I
Site 6
Y122
D
E
L
M
D
F
G
Y
P
Q
T
T
D
S
K
Site 7
Y134
D
S
K
I
L
Q
E
Y
I
T
Q
E
G
H
K
Site 8
T144
Q
E
G
H
K
L
E
T
G
A
P
R
P
P
A
Site 9
T152
G
A
P
R
P
P
A
T
V
T
N
A
V
S
W
Site 10
T154
P
R
P
P
A
T
V
T
N
A
V
S
W
R
S
Site 11
S158
A
T
V
T
N
A
V
S
W
R
S
E
G
I
K
Site 12
Y166
W
R
S
E
G
I
K
Y
R
K
N
E
V
F
L
Site 13
S192
A
N
G
N
V
L
R
S
E
I
V
G
S
I
K
Site 14
T223
D
K
V
L
F
D
N
T
G
R
G
K
S
K
S
Site 15
S228
D
N
T
G
R
G
K
S
K
S
V
E
L
E
D
Site 16
S230
T
G
R
G
K
S
K
S
V
E
L
E
D
V
K
Site 17
T252
S
R
F
E
N
D
R
T
I
S
F
I
P
P
D
Site 18
S254
F
E
N
D
R
T
I
S
F
I
P
P
D
G
E
Site 19
S266
D
G
E
F
E
L
M
S
Y
R
L
N
T
H
V
Site 20
Y267
G
E
F
E
L
M
S
Y
R
L
N
T
H
V
K
Site 21
S281
K
P
L
I
W
I
E
S
V
I
E
K
H
S
H
Site 22
S287
E
S
V
I
E
K
H
S
H
S
R
I
E
Y
M
Site 23
Y293
H
S
H
S
R
I
E
Y
M
I
K
A
K
S
Q
Site 24
S299
E
Y
M
I
K
A
K
S
Q
F
K
R
R
S
T
Site 25
S305
K
S
Q
F
K
R
R
S
T
A
N
N
V
E
I
Site 26
T306
S
Q
F
K
R
R
S
T
A
N
N
V
E
I
H
Site 27
S322
P
V
P
N
D
A
D
S
P
K
F
K
T
T
V
Site 28
T327
A
D
S
P
K
F
K
T
T
V
G
S
V
K
W
Site 29
T328
D
S
P
K
F
K
T
T
V
G
S
V
K
W
V
Site 30
S331
K
F
K
T
T
V
G
S
V
K
W
V
P
E
N
Site 31
S344
E
N
S
E
I
V
W
S
I
K
S
F
P
G
G
Site 32
S347
E
I
V
W
S
I
K
S
F
P
G
G
K
E
Y
Site 33
Y354
S
F
P
G
G
K
E
Y
L
M
R
A
H
F
G
Site 34
S364
R
A
H
F
G
L
P
S
V
E
A
E
D
K
E
Site 35
S377
K
E
G
K
P
P
I
S
V
K
F
E
I
P
Y
Site 36
Y384
S
V
K
F
E
I
P
Y
F
T
T
S
G
I
Q
Site 37
Y394
T
S
G
I
Q
V
R
Y
L
K
I
I
E
K
S
Site 38
Y403
K
I
I
E
K
S
G
Y
Q
A
L
P
W
V
R
Site 39
Y411
Q
A
L
P
W
V
R
Y
I
T
Q
N
G
D
Y
Site 40
T413
L
P
W
V
R
Y
I
T
Q
N
G
D
Y
Q
L
Site 41
Y418
Y
I
T
Q
N
G
D
Y
Q
L
R
T
Q
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation